Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sundeep Paruchury"'
Autor:
Nilesh Gaud, Tarun Sharma, Punit Marathe, Sheelendra Pratap Singh, Sundeep Paruchury, Sandhya Mandlekar, Rambabu Arla, Murali Subramanian, Vinay K. Holenarsipur, Priyadeep Bhutani, Sankara Sivaprasad, Jaydeep Sinha
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:385-397
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401d16c45f093a8780ed7da6e0f53970
https://doi.org/10.1002/bdd.1950
https://doi.org/10.1002/bdd.1950
Autor:
Ajay Saxena, Devang Shah, Roy Haskell, John Herbst, Matthew G. Soars, Murali Subramanian, Gajendra Singh Chowan, Sundeep Paruchury, Muralikrishna Matta, Punit Marathe, Sandhya Mandlekar
Publikováno v:
Drug Metabolism Letters. 8:109-118
The study presented here identified and utilized a panel of solubility enhancing excipients to enable the generation of flux data in the Human colon carcinoma (Caco-2) system for compounds with poor solubility. Solubility enhancing excipients Dimethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b108638533d2b8b8c38395d2ea18bd
https://doi.org/10.2174/1872312808666141127113055
https://doi.org/10.2174/1872312808666141127113055
Autor:
Basanth Lakshmaiah, Murali Subramanian, Snehasis Jana, Punit Marathe, Sundeep Paruchury, Rambabu Arla, Sandhya Mandlekar, Prasannakumar Katnapally, Sonia Pahwa, Shashyendra Singh Gautam, Kaushik Ghosh, Sheelendra Pratap Singh, Vadari Yoganand, Debarati Mazumder Tagore
Publikováno v:
Drug Metabolism and Disposition. 41:1425-1432
Intestinal alkaline phosphatases (IALPs) are widely expressed in the brush border of epithelial cells of the intestinal mucosa. Although their physiologic role is unclear, they are very significant when it comes to the release of bioactive parent fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e021f4aeda1ac4e2802fb4ba6019ea0
https://doi.org/10.1124/dmd.113.051987
https://doi.org/10.1124/dmd.113.051987
Autor:
Vinay K, Holenarsipur, Nilesh, Gaud, Jaydeep, Sinha, Sankara, Sivaprasad, Priyadeep, Bhutani, Murali, Subramanian, Sheelendra Pratap, Singh, Rambabu, Arla, Sundeep, Paruchury, Tarun, Sharma, Punit, Marathe, Sandhya, Mandlekar
Publikováno v:
Biopharmaceuticsdrug disposition. 36(6)
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee324df7f66f4693a7782827b0e6679c
https://pubmed.ncbi.nlm.nih.gov/25832562
https://pubmed.ncbi.nlm.nih.gov/25832562
Autor:
Ravikumar Nutakki, Prasanna Katnapally, Murali Subramanian, Chris Freeden, Sundeep Paruchury, Reeba K. Vikramadithyan, Indranil Rao, Priyadeep Bhutani, Vishwanath Kurawattimath, Punit Marathe, Chetan P Kulkarni, T. Thanga Mariappan, Pamela Abraham, Krishna Pocha, Sandhya Mandlekar
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 44(12)
1. The effect of age and obesity on the pharmacokinetics (PK), hepatic blood flow (HBF) and liver metabolism of 10 compounds was determined in rats. The animals fed a high-fat diet were defined as the diet-induced obese (DIO) group, while the animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16b2c5da3efcba3c9d20ff9b59ec45e
https://pubmed.ncbi.nlm.nih.gov/24947446
https://pubmed.ncbi.nlm.nih.gov/24947446