Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sunday N Okafor"'
Autor:
Melford C Egbujor, Uchechukwu C Okoro, Sunday N Okafor, Samuel A Egu, Ifeanyi S Amasiatu, Pius I Egwuatu, Odera R Umeh, Eziafakaego M Ibo
Publikováno v:
Research in Pharmaceutical Sciences, Vol 17, Iss 1, Pp 99-110 (2022)
Background and purpose: The preponderance of microbial infections remains a global challenge. In the present study, synthesis of novel cysteine-based antimicrobial agents and their biological evaluation is reported. Experimental approach: The reactio
Externí odkaz:
https://doaj.org/article/0d64314ccf004a3fa80c7ece308bcf91
Autor:
Kwanele A. Nxumalo, Jerry O. Adeyemi, Tshiamo B. Leta, Trust M. Pfukwa, Sunday N. Okafor, Olaniyi A. Fawole
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Significant postharvest losses and food safety issues persist in many developing nations, primarily due to fungal activities, including mycotoxin production. In this study, green synthesised zinc oxide nanoparticles (ZnO-NPs) were prepared f
Externí odkaz:
https://doaj.org/article/5fb5ebe4b6ac42d19743870f3740f9b7
Autor:
Tanzimjahan A. Saiyed, Jerry O. Adeyemi, Moganavelli Singh, Sunday N. Okafor, Damian C. Onwudiwe
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101052- (2023)
Eight new bipyridine adducts of Zn(II) and Ni(II) dithiocarbamate complexes have been prepared from the reaction of Zn(II) and Ni(II) complexes of N-ethyl-N-phenyldithiocarbamate and 4,4′ dipyridine, 4,4′-dimethyl-2,2′-bipyridine, 4,4′-dimeth
Externí odkaz:
https://doaj.org/article/8373a1bfb0f349dd9bde011e0dbb4e8a
Autor:
Sunday N. Okafor, Abigail Meyer, Jay Gadsden, Fadi Ahmed, Lilian Guzmán, Hashim Ahmed, José A. Fernández Romero, Pavimol Angsantikul
Publikováno v:
Molecules, Vol 28, Iss 17, p 6330 (2023)
The use of protease inhibitors in human immunodeficiency virus type 1 (HIV-1) treatment is limited by adverse effects, including metabolic complications. To address these challenges, efforts are underway in the pursuit of more potent and less toxic H
Externí odkaz:
https://doaj.org/article/f83a337ba5534398bbe2aab7a442938f
Autor:
Innocent U. Okagu, Timothy P. C. Ezeorba, Rita N. Aguchem, Ikenna C. Ohanenye, Emmanuel C. Aham, Sunday N. Okafor, Carlotta Bollati, Carmen Lammi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8468 (2022)
The drugs used for treating bone diseases (BDs), at present, elicit hazardous side effects that include certain types of cancers and strokes, hence the ongoing quest for the discovery of alternatives with little or no side effects. Natural products (
Externí odkaz:
https://doaj.org/article/51b97eb083364600b3142df81165ae35
Autor:
James A. Ezugwu, Uchechukwu C. Okoro, Mercy A. Ezeokonkwo, China R. Bhimapaka, Sunday N. Okafor, David I. Ugwu, Ogechi C. Ekoh, Solomon I. Attah
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The increase of antimicrobial resistance (AMR) and antimalarial resistance are complex and severe health issues today, as many microbial strains have become resistant to market drugs. The choice for the synthesis of new dipeptide-carboxamide derivati
Externí odkaz:
https://doaj.org/article/7a888c059bb3460bbae067df988c4f7a
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
A sequence of transition metal complexes of Mn(II), Co(II), Ni(II), and Cu(II) incorporating a novel pyrimidinyl based Schiff base ligand, 2-(4,6-dimethylpyrimidin-2-ylamino)naphthalene-1,4-dione (HL) and 2,2′-bipyridine has been synthesized and ch
Externí odkaz:
https://doaj.org/article/56b8c98ddc494031ac7185406da17278
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background The use of statin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for the treatment of dyslipidemia has been associated with dose limiting hepatoxicity, mytotoxicity and tolerability due to myalgias thereby necessitat
Externí odkaz:
https://doaj.org/article/18716c45156a4524b28b3b9e73649eef
Autor:
David Izuchukwu Ugwu, Uchechukwu Christopher Okoro, Pius Onyeoziri Ukoha, Astha Gupta, Sunday N. Okafor
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 405-415 (2018)
Twelve new derivatives of benzothiazole bearing benzenesulphonamide and carboxamide were synthesised and investigated for their in vivo anti-inflammatory, analgesic and ulcerogenic activities. Molecular docking showed an excellent binding interaction
Externí odkaz:
https://doaj.org/article/00a3e11f09ec4901b08abffa2b3140df
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Bacterial resistance to antibiotics has become one of the most challenging problems of infectious disease treatment. Ten new derivatives of benzenesulphonamide bearing carboxamide functionality were synthesized and investigated for their in vivo anti
Externí odkaz:
https://doaj.org/article/a37a950cc2bb4214867e0be8a7eda364