Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sundary Sormendi"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9191 (2021)
Every cell in the body requires oxygen for its functioning, in virtually every animal, and a tightly regulated system that balances oxygen supply and demand is therefore fundamental. The vascular network is one of the first systems to sense oxygen, a
Externí odkaz:
https://doaj.org/article/e28745681038445b85e4cb7b289cb41f
Autor:
Deepika Watts, Diana Gaete, Diego Rodriguez, David Hoogewijs, Martina Rauner, Sundary Sormendi, Ben Wielockx
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8131 (2020)
Erythropoiesis is a complex process driving the production of red blood cells. During homeostasis, adult erythropoiesis takes place in the bone marrow and is tightly controlled by erythropoietin (EPO), a central hormone mainly produced in renal EPO-p
Externí odkaz:
https://doaj.org/article/d92d559385ff440fbc1f5f4fcd65b453
Autor:
Sundary Sormendi, Ben Wielockx
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Low oxygen tension or hypoxia is a determining factor in the course of many different processes in animals, including when tissue expansion and cellular metabolism result in high oxygen demands that exceed its supply. This is mainly happening when ce
Externí odkaz:
https://doaj.org/article/0a8ab86f7199472da03edd448c401b26
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9191, p 9191 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Every cell in the body requires oxygen for its functioning, in virtually every animal, and a tightly regulated system that balances oxygen supply and demand is therefore fundamental. The vascular network is one of the first systems to sense oxygen, a
Autor:
Anja Krüger, Pablo J. Sáez, Alessandra Palladini, Ünal Coskun, Ioannis Kourtzelis, Ben Wielockx, Pablo Vargas, Jochen Guck, Sundary Sormendi, Gregoire Le Lay, Triantafyllos Chavakis, Ana Meneses, Mathilde Bernard, Martin Kräter, Anupam Sinha, Michael Gerlach, Mathieu Deygas, Kristin Franke
Publikováno v:
Blood 137, 3416-3427 (2021)
Blood
Blood
Orchestrated recruitment of neutrophils to inflamed tissue is essential during initiation of inflammation. Inflamed areas are usually hypoxic, and adaptation to reduced oxygen pressure is typically mediated by hypoxia pathway proteins. However, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a16d554cddb1928ac205c116569a3b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61487
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61487
Autor:
Diana Gaete, Ben Wielockx, Sundary Sormendi, Deepika Watts, Diego Rodriguez, Triantafyllos Chavakis
Solid tumors are typically associated with unbridled proliferation of malignant cells, accompanied by an immature and dysfunctional tumor-associated vascular network. Consequent impairment in transport of nutrients and oxygen eventually leads to a hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ca547ad5577ca528b7ff59c0dc649d
Autor:
Diana Gaete, Deepika Watts, David Hoogewijs, Diego Rodriguez, Ben Wielockx, Sundary Sormendi, Martina Rauner
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8131, p 8131 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 8131, p 8131 (2020)
Erythropoiesis is a complex process driving the production of red blood cells. During homeostasis, adult erythropoiesis takes place in the bone marrow and is tightly controlled by erythropoietin (EPO), a central hormone mainly produced in renal EPO-
Autor:
George Hajishengallis, Triantafyllos Chavakis, Sevina Dietz, Peter Mirtschink, Peter J. Murray, Athanasios Ziogas, Marina Nati, Kyoung-Jin Chung, Ioannis Kourtzelis, Ben Wielockx, Eman Hagag, Panayotis Verginis, Ales Neuwirth, Mihai G. Netea, Jonas Schulte-Schrepping, Ian Henry, Pallavi Subramanian, Joachim L. Schultze, Tatyana Grinenko, Canan Has, Antonios Chatzigeorgiou, Sundary Sormendi, Anupam Sinha, Ioannis Mitroulis, Xiaofei Li, Lydia Kalafati, Aikaterini Hatzioannou, Andreas Dahl, António Miguel de Jesus Domingues, Mathias Lesche
Publikováno v:
Cell, 183, 3, pp. 771-785.e12
Cell, 183, 771-785.e12
Cell 183(3), 771-785.e12 (2020). doi:10.1016/j.cell.2020.09.058
Cell
Kalafati, L, Kourtzelis, I, Schulte-Schrepping, J, Li, X, Hatzioannou, A, Grinenko, T, Hagag, E, Sinha, A, Has, C, Dietz, S, de Jesus Domingues, A M, Nati, M, Sormendi, S, Neuwirth, A, Chatzigeorgiou, A, Ziogas, A, Lesche, M, Dahl, A, Henry, I, Subramanian, P, Wielockx, B, Murray, P, Mirtschink, P, Chung, K-J, Schultze, J L, Netea, M G, Hajishengallis, G, Verginis, P, Mitroulis, I & Chavakis, T 2020, ' Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity ', Cell, vol. 183, no. 3, pp. 771-785 . https://doi.org/10.1016/j.cell.2020.09.058
Cell, 183, 771-785.e12
Cell 183(3), 771-785.e12 (2020). doi:10.1016/j.cell.2020.09.058
Cell
Kalafati, L, Kourtzelis, I, Schulte-Schrepping, J, Li, X, Hatzioannou, A, Grinenko, T, Hagag, E, Sinha, A, Has, C, Dietz, S, de Jesus Domingues, A M, Nati, M, Sormendi, S, Neuwirth, A, Chatzigeorgiou, A, Ziogas, A, Lesche, M, Dahl, A, Henry, I, Subramanian, P, Wielockx, B, Murray, P, Mirtschink, P, Chung, K-J, Schultze, J L, Netea, M G, Hajishengallis, G, Verginis, P, Mitroulis, I & Chavakis, T 2020, ' Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity ', Cell, vol. 183, no. 3, pp. 771-785 . https://doi.org/10.1016/j.cell.2020.09.058
Summary Trained innate immunity, induced via modulation of mature myeloid cells or their bone marrow progenitors, mediates sustained increased responsiveness to secondary challenges. Here, we investigated whether anti-tumor immunity can be enhanced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c637a504dcda3e4fee30ef1cda9f210
https://hdl.handle.net/2066/228705
https://hdl.handle.net/2066/228705
Autor:
Maria Xilouri, Panayotis Verginis, Konstantinos Mintzas, Aggelos Banos, Helen Gogas, Ben Wielockx, Sundary Sormendi, Aikaterini Hatzioannou, Themis Alissafi, Alexandros Polyzos, Roza Maria Barouni
Publikováno v:
Journal of Clinical Investigation. 128:3840-3852
Myeloid-derived suppressor cells (MDSCs) densely accumulate into tumors and potently suppress antitumor immune responses, promoting tumor development. Targeting MDSCs in tumor immunotherapy has been hampered by lack of understanding of the molecular
Autor:
Sundary Sormendi, Ben Wielockx
Publikováno v:
Translational Cancer Research. 5:S1503-S1508