Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer.

Autor: Soundararajan R; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Maurin MM; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Rodriguez-Silva J; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Upadhyay G; Department of Internal Medicine, University of South Florida Health, Tampa, Florida, USA., Alden AJ; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Gowda SGB; Faculty of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sappora, Japan., Schell MJ; Biostatistics and Bioinformatics Department, Moffitt Cancer Center, Tampa, Florida, USA., Yang M; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Levine NJ; Center for Phenom Health, Buck Institute for Research on Aging, Novato, California, USA., Gowda D; Faculty of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sappora, Japan., Sundaraswamy PM; Graduate School of Global Food Resources, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo, Japan., Hui SP; Faculty of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sappora, Japan., Pflieger L; Center for Phenom Health, Buck Institute for Research on Aging, Novato, California, USA., Wang H; Department of Surgery, University of South Florida Health, Tampa, Florida, USA., Marcet J; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Martinez C; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Bennett RD; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Chudzinski A; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Karachristos A; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Nywening TM; Division of Surgical Oncology, Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Cavallaro PM; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Anderson ML; Department of Surgery, Tampa General Hospital, Tampa, Florida, USA., Coffey RJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Nebozhyn MV; Merck Research Laboratories Boston, Boston, Massachusetts, USA., Loboda A; Merck Research Laboratories Boston, Boston, Massachusetts, USA., Coppola D; Department of Pathology, Florida Digestive Health Specialists LLP, Bradenton, Florida, USA., Pledger WJ; Tampa General Hospital, Tampa, Florida, USA.; Department of Molecular Medicine, University of South Florida Health, Tampa, Florida, USA., Halade G; Department of Internal Medicine, University of South Florida Health, Tampa, Florida, USA., Yeatman TJ; Department of Surgery, University of South Florida Health, Tampa, Florida, USA yeatman7383@gmail.com.

Publikováno v: Gut [Gut] 2024 Dec 10. Date of Electronic Publication: 2024 Dec 10.