Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sundaramurthy Pandurangan"'
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 86-92 (2017)
The quest to develop computational drug target identification methods in complex diseases like cancer is growing in recent years. Feedback, feed-forward loops and cross-talks observed among the MAPK pathways led to the definition of a network of MAPK
Externí odkaz:
https://doaj.org/article/482f5e3cb87942608593a82298521c56
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 173-180 (2017)
Proteins involved in the cross-talk between ERK1/2, ERK5, JNK, and P38 signalling pathways integrate the network of Mitogen-Activated Protein Kinase (MAPK) pathways. Graph theory-based approach is used to construct the network of MAPK pathways, and t
Externí odkaz:
https://doaj.org/article/e552517835c44dd4b5c6f422ad5a31a6
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 173-180 (2017)
Proteins involved in the cross-talk between ERK1/2, ERK5, JNK, and P38 signalling pathways integrate the network of Mitogen-Activated Protein Kinase (MAPK) pathways. Graph theory-based approach is used to construct the network of MAPK pathways, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c82fac95545271bf5a4a2d39dd58a79
https://doi.org/10.1016/j.imu.2017.08.006
https://doi.org/10.1016/j.imu.2017.08.006
Publikováno v:
International Journal of Bioinformatics Research and Applications. 17:69
Computational side-effect prediction tools assist in rational drug design to decrease the late-stage failure of the drugs. Irrational selection of cancer drug targets in the deregulated MAPK pathways causes side effects. Network centralities and biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd1a33d28d69b97c000df5c69b73103
https://doi.org/10.1504/ijbra.2021.113963
https://doi.org/10.1504/ijbra.2021.113963
Autor:
Sundaramurthy, Pandurangan1,2,3 pksmurthy@ncbs.res.in, Shameer, Khader1 shameer@ncbs.res.in, Sreenivasan, Raashi1,4,5 sraashi@ncbs.res.in, Gakkhar, Sunita2 sungkfma@iitr.ernet.in, Sowdhamini, Ramanathan1 mini@ncbs.res.in
Publikováno v:
BMC Bioinformatics. 2010 Supplement 1, Vol. 11, Special section p1-9. 9p. 2 Color Photographs, 1 Diagram, 1 Chart.
Publikováno v:
IEEE/ACM Transactions on Computational Biology and Bioinformatics. :1-1
Proteins in the MAPK pathways considered as potential drug targets for cancer treatment. Pathways along with the cross-talks increase their scope to view them as a network of MAPK pathways. Side effect causing targeted domains act as a proxy for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15aff04cbdd1d79e25f280749f3c9bc
https://doi.org/10.1109/tcbb.2018.2829507
https://doi.org/10.1109/tcbb.2018.2829507
Kinase cascades in ERK5 (Extracellular signal-regulated kinases) and JNK (c-Jun N-terminal kinases) signaling pathways mediate the sensing and processing of stimuli. Cross-talks between signaling cascades is a likely phenomenon that can cause apparen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a5c621b27b1172faa8e1b019d55db1
https://europepmc.org/articles/PMC2923301/
https://europepmc.org/articles/PMC2923301/
Autor:
Raashi Sreenivasan, Sundaramurthy Pandurangan, Shameer Khader, Sunita Gakkhar, Sowdhamini Ramanathan
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f692a706a25f4a8519dd89f9ec99ab71
https://doi.org/10.1038/nprot.2010.91
https://doi.org/10.1038/nprot.2010.91
Akademický článek
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Autor:
Kotaru AR; Department of Electronics and Computer Engineering, Indian Institute of Technology Roorkee, 247667, Roorkee, India., Shameer K, Sundaramurthy P, Joshi RC
Publikováno v:
Bioinformation [Bioinformation] 2013 Apr 13; Vol. 9 (7), pp. 368-74. Date of Electronic Publication: 2013 Apr 13 (Print Publication: 2013).