Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sundaram Reddy Chakkarappan"'
Autor:
Shankar Dhamodharan, Mathew Maria Rose, Sundaram Reddy Chakkarappan, Karuppiah Vijayamuthuramalingam Umadharshini, Ramalingam Arulmurugan, Shanmugam Subbiah, Ituro Inoue, Arasambattu Kannan Munirajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Tyrosine kinase inhibitor is an effective chemo-therapeutic drug against tumors with deregulated EGFR pathway. Recently, a genetic variant rs10251977 (G>A) in exon 20 of EGFR reported to act as a prognostic marker for HNSCC. Genotyping of th
Externí odkaz:
https://doaj.org/article/faff5b05fc5f4e8b8985d90024ca286f
Autor:
Mathew Maria Rose, Shankar Dhamodharan, Sundaramoorthy Revathidevi, Sundaram Reddy Chakkarappan, Mani G Jagadeesan, Shanmugam Subbiah, Hirofumi Nakaoka, Ituro Inoue, Avaniyapuram Kannan Murugan, Arasambattu Kannan Munirajan
Publikováno v:
Cancer Genetics. :100-108
Cervical cancer is the second most common cancer in India. The phosphatidylinositol-3 kinase (PI3K) signaling is one of the most commonly activated pathways in cancer and comprises key molecules commonly targeted in cancer therapy. This study analyze
Autor:
Miaomiao Suo, Megan K. Rommelfanger, Yulin Chen, Elias Moris Amro, Bing Han, Zhiyang Chen, Karol Szafranski, Sundaram Reddy Chakkarappan, Bernhard O. Boehm, Adam L. MacLean, K. Lenhard Rudolph
Publikováno v:
Blood. 139:2653-2665
Increasing evidence links metabolism, protein synthesis, and growth signaling to impairments in the function of hematopoietic stem and progenitor cells (HSPCs) during aging. The Lin28b/Hmga2 pathway controls tissue development, and the postnatal down
Autor:
Shanmugam Subbiah, Sundaram Reddy Chakkarappan, Mathew Maria Rose, Ituro Inoue, Shankar Dhamodharan, Ramalingam Arulmurugan, Karuppiah Vijayamuthuramalingam Umadharshini, Arasambattu Kannan Munirajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Tyrosine kinase inhibitor is an effective chemo-therapeutic drug against tumors with deregulated EGFR pathway. Recently, a genetic variant rs10251977 (G>A) in exon 20 of EGFR reported to act as a prognostic marker for HNSCC. Genotyping of this polymo
Autor:
Dhamodharan Shankar, Rose Mathew, Sundaram Reddy Chakkarappan, Uma Dharshini Karuppiah Vijayamuthuramalingam, Arulmurugan Ramalingam, Subbiah Shanmugam, Inoue Ituro, Munirajan Arasambattu
Tyrosine kinase inhibitor (TKI) is one of the effective chemo-preventive approaches against tumors that deregulate EGFR pathway. About 80% of HNSCC patients overexpress EGFR, making TKI an effective treatment against this cancer. Recently a synonymou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c53728d0e923377df340e4f508aad5c4
https://doi.org/10.21203/rs.3.rs-136285/v1
https://doi.org/10.21203/rs.3.rs-136285/v1
Akademický článek
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Autor:
Sundaram, Reddy Chakkarappan
The G0/G1 switch gene 2 (G0s2) has putative roles in cellular proliferation and fat metabolism. While activated blood mononuclear cells increase the expression of G0S2, cancer cells silence it by promoter methylation. Moreover, G0S2 was shown to act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf0e9ccd9b49fdd3c07a893169facdc
Autor:
Rui Wang Sattler, Bernhard O. Böhm, Zhangfa Song, Tina Wenz, Tina M. Binz, Susanne Klaus, Karsten Hiller, Martin D. Burkhalter, Pavlos Missios, Cagatay Günes, Anne Gompf, Veronika Wulff, Guido von Figura, Thomas Illig, Götz Hartleben, Sundaram Reddy Chakkarappan, Andre Wegner, Yuan Zhou, Luis Miguel Guachalla, K. Lenhard Rudolph
Publikováno v:
Nature Communications, 5: 4924
Nature Communications
Nat. Commun. 5:4924 (2014)
Nature Communications
Nat. Commun. 5:4924 (2014)
DNA damage and telomere dysfunction shorten organismal lifespan. Here we show that oral glucose administration at advanced age increases health and lifespan of telomere dysfunctional mice. The study reveals that energy consumption increases in telome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a197a7ea2ae169e52f2737c35e836446
https://repository.publisso.de/resource/frl:6405909
https://repository.publisso.de/resource/frl:6405909
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.