Výsledky vyhledávání - "Sundar Durai"

Akademický článek

In silico engineering of aggregation-prone recombinant proteins for substrate recognition by the chaperonin GroEL

Autor: Kumar Vipul, Punetha Ankita, Sundar Durai, Chaudhuri Tapan K

Publikováno v: BMC Genomics, Vol 13, Iss Suppl 7, p S22 (2012)

Abstract Background Molecular chaperones appear to have been evolved to facilitate protein folding in the cell through entrapment of folding intermediates on the interior of a large cavity formed between GroEL and its co-chaperonin GroES. They bind n

Externí odkaz: https://doaj.org/article/7b410d0089e3427c9ada2fc848684942

Zobrazit plný text záznamu

Akademický článek

TCR-ESM: Employing protein language embeddings to predict TCR-peptide-MHC binding

Autor: Yadav, Shashank, Vora, Dhvani Sandip, Sundar, Durai, Dhanjal, Jaspreet Kaur

Publikováno v: In Computational and Structural Biotechnology Journal December 2024 23:165-173

Zobrazit plný text záznamu

Akademický článek

Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A

Autor: Grover Abhinav, Agrawal Vibhuti, Shandilya Ashutosh, Bisaria Virendra S, Sundar Durai

Publikováno v: BMC Bioinformatics, Vol 12, Iss Suppl 13, p S22 (2011)

Abstract Background Herpes Simplex Virus 1 and 2 causes several infections in humans including cold sores and encephalitis. Previous antiviral studies on herpes viruses have focussed on developing nucleoside analogues that can inhibit viral polymeras

Externí odkaz: https://doaj.org/article/c328b931b9f041628e2a11b37eb37666

Zobrazit plný text záznamu

Akademický článek

The G protein-coupled receptors in the pufferfish Takifugu rubripes

Autor: Sundar Durai, Kumar Sonu, Sarkar Anita

Publikováno v: BMC Bioinformatics, Vol 12, Iss Suppl 1, p S3 (2011)

Abstract Background Guanine protein-coupled receptors (GPCRs) constitute a eukaryotic transmembrane protein family and function as “molecular switches” in the second messenger cascades and are found in all organisms between yeast and humans. They

Externí odkaz: https://doaj.org/article/f220b201ada046f7a23073199e7a91ee

Zobrazit plný text záznamu

Akademický článek

Hsp90/Cdc37 Chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A

Autor: Bisaria Virendra S, Bhasme Divya, Pratik Piyush, Agrawal Vibhuti, Shandilya Ashutosh, Grover Abhinav, Sundar Durai

Publikováno v: BMC Bioinformatics, Vol 12, Iss Suppl 1, p S30 (2011)

Abstract Background HSPs (Heat shock proteins) are highly conserved ubiquitous proteins among species which are involved in maintaining appropriate folding and conformation of other proteins and are thus referred to as molecular chaperones. Hsp90 (He

Externí odkaz: https://doaj.org/article/891bb06103f24978a6a7923e2617ca92

Zobrazit plný text záznamu

Akademický článek

Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes

Autor: Bisaria Virendra S, Shandilya Ashutosh, Grover Abhinav, Sundar Durai

Publikováno v: BMC Genomics, Vol 11, Iss Suppl 4, p S15 (2010)

Abstract Background The UPP (ubiquitin proteasome pathway) is the major proteolytic system in the cytosol and nucleus of all eukaryotic cells which regulates cellular events, including mitotis, differentiation, signal transduction, apoptosis, and inf

Externí odkaz: https://doaj.org/article/95b2402469c94253bde24d0fd1c495b5

Zobrazit plný text záznamu