Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Sunao Takeshita"'
Autor:
Yifan Qing, Takehito Ono, Yukihiro Kohara, Atsushi Watanabe, Noboru Ogiso, Masako Ito, Tomoki Nakashima, Sunao Takeshita
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-15 (2024)
Abstract Background Regeneration of injured tissue is dependent on stem/progenitor cells, which can undergo proliferation and maturation processes to replace the lost cells and extracellular matrix (ECM). Bone has a higher regenerative capacity than
Externí odkaz:
https://doaj.org/article/bdc545330fcc40dbbe297c70534e12cc
Autor:
Kyoji Ikeda, Sunao Takeshita, Atsushi Watanabe, Masako Ito, Yoshinori Naoe, Kazuhiko Matsuoka, Yukihiro Kohara
Publikováno v:
Journal of Bone and Mineral Research. 33:1500-1512
The osteoclast-derived collagen triple helix repeat containing 1 (CTHRC1) protein stimulates osteoblast differentiation, but the underlying mechanism remains unclear. Here, we identified Wnt-activated inhibitory factor 1 (WAIF1)/5T4 as a cell-surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7978a332bd11e43e9e0141521d43a592
https://doi.org/10.1002/jbmr.3436
https://doi.org/10.1002/jbmr.3436
Autor:
Kevin Yan, Caterina Iorio, Wentian Yang, Sumin Kang, Lijun Wang, Benjamin G. Neel, Howard Yang, Sunao Takeshita
Publikováno v:
The FASEB Journal. 32:875-887
Activation of the RAS/ERK and its downstream signaling components is essential for growth factor-induced cell survival, proliferation, and differentiation. The Src homology-2 domain containing protein tyrosine phosphatase 2 (SHP2), encoded by protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdab395653c16b525b3e21911521a66
https://doi.org/10.1096/fj.201700672rr
https://doi.org/10.1096/fj.201700672rr
Autor:
Kyoji Ikeda1, Sunao Takeshita1 sunao@ncgg.go.jp
Publikováno v:
Journal of Biochemistry. Jan2016, Vol. 159 Issue 1, p1-8. 8p. 4 Color Photographs.
Autor:
Kazuhiko, Matsuoka, Yukihiro, Kohara, Yoshinori, Naoe, Atsushi, Watanabe, Masako, Ito, Kyoji, Ikeda, Sunao, Takeshita
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33(8)
The osteoclast-derived collagen triple helix repeat containing 1 (CTHRC1) protein stimulates osteoblast differentiation, but the underlying mechanism remains unclear. Here, we identified Wnt-activated inhibitory factor 1 (WAIF1)/5T4 as a cell-surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20129b67c990f34c6f9598585fd68c97
https://pubmed.ncbi.nlm.nih.gov/29624737
https://pubmed.ncbi.nlm.nih.gov/29624737
Publikováno v:
Biochemical and Biophysical Research Communications. 462:159-164
In an attempt to identify secretory products of osteoclasts that mediate the coupling of bone formation to resorption, we found that along with osteoclast differentiation, PDGF-A gene expression increase occurred first, by 12 h after stimulation of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c5d3927667c47f0917ccd58e4f0cf4
https://doi.org/10.1016/j.bbrc.2015.04.115
https://doi.org/10.1016/j.bbrc.2015.04.115
Autor:
Sunao, Takeshita
Publikováno v:
Clinical calcium. 27(12)
Preceding bone resorption is a prerequisite for the initiation of subsequent bone formation during adulthood and the quantity as well as the quality of bone is maintained by which newly formed bone by osteoblasts replaces precisely the amount removed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d46bdbed17374b5a07517ca5dec8f25e
https://pubmed.ncbi.nlm.nih.gov/29179164
https://pubmed.ncbi.nlm.nih.gov/29179164
Publikováno v:
Journal of Bone and Mineral Research. 29:1522-1530
Bone remodeling is regulated by a coupling of resorption to subsequent formation; however, the "coupling factor" and underlying mechanism are not fully understood. Here, we found that the condition medium (CM) of mature osteoclasts contains a humoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30c6733a03aed2c3ecce393f51ea8d0
https://doi.org/10.1002/jbmr.2187
https://doi.org/10.1002/jbmr.2187
Publikováno v:
Journal of Biological Chemistry. 289:16699-16710
With advancing age bone marrow is progressively replaced with adipose tissue, accompanied by a concomitant decline in bone mass and strength. The mechanism underlying the increase in marrow fat and bone destruction remains elusive. We found that on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fed6ff216019ae054cfa0b7630a0a29
https://doi.org/10.1074/jbc.m114.547919
https://doi.org/10.1074/jbc.m114.547919
Publikováno v:
Journal of Bone and Mineral Research. 29:830-842
The cytokine RANKL is essential for osteoclast development in bone. The cellular sources of RANKL for support of osteoclast generation under various pathophysiological conditions have remained unclear, however. Here we show that inactivation of Rankl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda68e7510a5e3fd45da64822fa463e5
https://doi.org/10.1002/jbmr.2096
https://doi.org/10.1002/jbmr.2096