Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sunandini Sridhar"'
Autor:
Brooke A. Conti, Penelope D. Ruiz, Cayla Broton, Nicolas J. Blobel, Molly C. Kottemann, Sunandini Sridhar, Francis P. Lach, Tom F. Wiley, Nanda K. Sasi, Thomas Carroll, Agata Smogorzewska
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract DNA replication through a challenging genomic landscape is coordinated by the replisome, which must adjust to local conditions to provide appropriate replication speed and respond to lesions that hinder its progression. We have previously sh
Externí odkaz:
https://doaj.org/article/bb0f43ef23d34a678edc5ee4e00c721c
Publikováno v:
BioTechniques, Vol 41, Iss 1, Pp 59-63 (2006)
A number of natural microRNA (miRNA) hairpins have been found in clusters of multiple identical or different copies, suggesting that effects of miRNAs can be enhanced and multiple genes can be regulated together by encoding multiple miRNA hairpins in
Externí odkaz:
https://doaj.org/article/614c63e77ba546378c7d7c7be816a861
Autor:
Andrew L. H. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Remco M. Hoogenboezem, Moonjung Jung, Sunandini Sridhar, Tom F. Wiley, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer A. Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas S. Carroll, Sanjana Shroff, Michael Beaumont, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Kristin G. Beaumont, Amnon Koren, Marcin Imielinski, Settara C. Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David I. Kutler, Peter J. Campbell, Agata Smogorzewska
Publikováno v:
Nature, 612(7940), 495-502. Nature Publishing Group
Nature
Nature
Fanconi anaemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink repair resulting in chromosome breakage1–3. The FA repair pathway protects against endogenous and exogenous carcinogenic aldehydes4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15cd1011ef44b739a461beaa02a1cb6
https://doi.org/10.1038/s41586-022-05253-4
https://doi.org/10.1038/s41586-022-05253-4
Autor:
Brooke A. Conti, Penelope D. Ruiz, Cayla Broton, Nicolas J. Blobel, Molly C. Kottemann, Sunandini Sridhar, Francis P. Lach, Tom Wiley, Nanda K. Sasi, Thomas Carroll, Agata Smogorzewska
Publikováno v:
bioRxiv
Genetic information is duplicated via the highly regulated process of DNA replication. The machinery coordinating this process, the replisome, encounters many challenges, including replication fork-stalling lesions that threaten the accurate and time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da392f37a28108837fa33207a1cb1cd
https://europepmc.org/articles/PMC10054921/
https://europepmc.org/articles/PMC10054921/
Autor:
Moonjung Jung, Isaac Ilyashov, Yeji Park, Frank X. Donovan, Ramanagouda Ramanagoudr-Bhojappa, Danielle Keahi, Jordan A. Durmaz, Haruna B. Choijilsuren, Audrey Goldfarb, Mia Stein, Jungwoo Kim, Ryan R. White, Sunandini Sridhar, Raymond Noonan, Tom Wiley, Thomas S. Carroll, Francis P. Lach, Arleen D. Auerbach, Ileana Miranda, Settara C. Chandrasekharappa, Agata Smogorzewska
Fanconi anemia (FA) pathway is required for the repair of DNA interstrand crosslinks (ICL). ICLs are caused by genotoxins, such as chemotherapeutic agents or reactive aldehydes. Inappropriately repaired ICLs contribute to hematopoietic stem cell (HSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e41f275ac67d6f99de7a0e72927d99
https://doi.org/10.1101/2022.05.26.493623
https://doi.org/10.1101/2022.05.26.493623
Autor:
Sunandini Sridhar, David I. Kutler, Bhuvanesh Singh, Susanne I. Wells, Ji-Dung Luo, Mathijs A. Sanders, Margaret L. MacMillan, Ashlyn-Maree Gonzalez, Lorenzo Bean, Rebecca Tryon, Huasong Tian, Jordi Surrallés, Arleen D. Auerbach, Kevin Hadi, Moonjung Jung, Ralf Dietrich, Matthew M. Edwards, Eunike Velleuer, Krupa R. Patel, Frank X. Donovan, Amnon Koren, Marcin Imielinski, Audrey Goldfarb, Ozgur Rosti, Jeffrey C. Rastatter, Theresa Scognamiglio, John E. Wagner, Andrew L.H. Webster, Maria Cancio, Olivier Fedrigo, Agata Smogorzewska, Jennifer A. Kennedy, Thomas Carrol, Grover C. Bagby, Joel Rosiene, Allana Rosenberg, Thomas Heineman, Ryan R. White, Raymond J. Noonan, Farid Boulad, Francis P. Lach, Settara C. Chandrasekharappa, Peter J. Campbell, Roger D. Vaughan
Fanconi anemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink (ICL) repair resulting in chromosome breakage1–3. The FA repair pathway comprises at least 22 FANC proteins including BRCA1 and BRCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9afd781051fca6c3cb7bdbe0af4e0c0
https://doi.org/10.1101/2021.08.14.456365
https://doi.org/10.1101/2021.08.14.456365
Autor:
Andrew L. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey M. Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Moonjung Jung, Sunandini Sridhar, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas Carrol, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Amnon Koren, Marcin Imielinski, Settara Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David Kutler, Peter J. Campbell, Agata Smogorzewska
Publikováno v:
Cancer Research. 82:6196-6196
Fanconi anemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink (ICL) repair resulting in chromosome breakage. The FA repair pathway comprises at least 22 FANC proteins including BRCA1 and BRCA2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93046854d732003d6d22f0ca29e784e7
https://doi.org/10.1158/1538-7445.am2022-6196
https://doi.org/10.1158/1538-7445.am2022-6196
Autor:
Marina A. Bellani, Yanglu Chen, Supawat Thongthip, Siobhan Q. Gregg, Agata Smogorzewska, Sunandini Sridhar, Michael M. Seidman, Brooke A. Conti
Publikováno v:
Genes & Development. 30:645-659
Deficiency of FANCD2/FANCI-associated nuclease 1 (FAN1) in humans leads to karyomegalic interstitial nephritis (KIN), a rare hereditary kidney disease characterized by chronic renal fibrosis, tubular degeneration, and characteristic polyploid nuclei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c07284f743e0ffee0f5e9fcbf9f77b
https://doi.org/10.1101/gad.276261.115
https://doi.org/10.1101/gad.276261.115
Autor:
Tom Wiley, Sunandini Sridhar, Danielle Keahi, Audrey Goldfarb, Agata Smogorzewska, Moonjung Jung, Raymond J. Noonan, Francis P. Lach, Ryan R. White
Publikováno v:
Blood. 134:106-106
Fanconi anemia (FA) is the most common inherited bone marrow failure (BMF) syndrome. Impaired DNA interstrand crosslink (ICL) repair is the underlying mechanism for BMF in FA. FA patients usually develop BMF during the first decade of life, prior to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6efc8c5df42097195e1c17b095f4bd7e
https://doi.org/10.1182/blood-2019-127686
https://doi.org/10.1182/blood-2019-127686