Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sunam Mander"'
Autor:
Sunam Mander, Samer A. Naffouje, Jin Gao, Weiguo Li, Konstantin Christov, Albert Green, Ernesto R. Bongarzone, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Despite recent advances in cancer research, glioblastoma multiforme (GBM) remains a highly aggressive brain tumor as its treatment options are limited. The current standard treatment includes surgery followed by radiotherapy and adjuvant chemotherapy
Externí odkaz:
https://doaj.org/article/c8c5606c174b491ca4ad1ddca4b6f72f
Autor:
Masahide Goto, Ingeun Ryoo, Samer Naffouje, Sunam Mander, Konstantin Christov, Jing Wang, Albert Green, Anne Shilkaitis, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103850- (2022)
Summary: Background: Given the lack of visual discrepancy between malignant and surrounding normal tissue, current breast conserving surgery (BCS) is associated with a high re-excision rate. Due to the increasing cases of BCS, a novel method of compl
Externí odkaz:
https://doaj.org/article/f4daa1d6aa3448d8a9e2e7591f0165bb
Autor:
Sunam Mander, Gregory S Gorman, Lori U Coward, Konstantin Christov, Albert Green, Tapas K Das Gupta, Tohru Yamada
Publikováno v:
Neuro-Oncology Advances. 5
Background Brain metastases (BMs), the most common tumors of the central nervous system, are life-threatening with a dismal prognosis. The major challenges to developing effective treatments for BMs are the limited abilities of drugs to target tumors
Autor:
Lan Phuong Nguyen, Hyo Jeong Yong, Hyo Kyeong Cha, Dong Hwi Kim, Sunam Mander, Hee Kyung Park, Huong Thi Nguyen, Won Ki Kim, Jong Ik Hwang
Publikováno v:
Biomolecules & Therapeutics
Liver cancer is a common tumor and currently the second leading cause of cancer-related mortality globally. Liver cancer is highly related to inflammation as more than 90% of liver cancer arises in the context of hepatic inflammation, such as hepatit
Autor:
Yun Hee Kim, Dong Joo You, Curie Ahn, Jong Ik Hwang, Dong Sik Kim, Dong Hwi Kim, Jae Young Seong, Sunam Mander, Sumi Park, Hyo Jeong Yong
Publikováno v:
Archives of Pharmacal Research. 41:229-242
Triple-negative breast cancer (TNBC) lacking of oestrogen receptor, progesterone receptor, and epidermal growth factor receptor type 2 is a highly malignant disease which results in a poor prognosis and rare treatment options. Despite the use of conv
Autor:
Won Ki Kim, Jae Young Seong, Kiho Lee, Dong Hwi Kim, Huong Thi Nguyen, Kisoo Pahk, Sunam Mander, Jong Ik Hwang, Hyo Jeong Yong, Eun Yeong Kim
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Breast cancer exhibits high lethality in women because it is frequently detected at an advanced stage and aggressive forms such as triple-negative breast cancer (TNBC), which are often characterized by metastasis through colonization of secondary tum
Publikováno v:
Molecules and Cells
NME1 is a well-known metastasis suppressor which has been reported to be downregulated in some highly aggressive cancer cells. Although most studies have focused on NME1, the NME1 gene also encodes the protein (NME1L) containing N-terminal 25 extra a
Autor:
Dong Joo You, Cho Rong Park, Jong Ik Hwang, Jae Young Seong, Sunam Mander, Curie Ahn, Cheolju Lee, Seong Hyun Oh, Ok Jae Koo
Publikováno v:
Journal of Cellular Biochemistry. 117:1454-1463
Non-metastatic cells 1 (NME1) or nm23 is the first metastasis suppressor gene discovered. It functions through various enzymatic activities and interacts with many intracellular proteins. The NME1 gene encodes two splicing variants, NME1 and NME1L. M
Autor:
Jong Ik Hwang, Sumi Park, Cho Rong Park, Da Eun Jang, Su Cheong Yeom, Curie Ahn, Sang Heon Lee, Dong Joo You, Sunam Mander, Jae Young Seong, Seong Hyun Oh
Publikováno v:
Scientific Reports
Some G-protein-coupled receptors have been reported to require accessory proteins with specificity for proper functional expression. In this study, we found that CXCR1 interacted with REEP5 and REEP6, but CXCR2 did not. Overexpression of REEP5 and RE