Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sunaina P. Nayak"'
Autor:
Jennifer R. Molina, Joseph M. Gozgit, Melissa M. Vasbinder, Ryan P. Abo, Kaiko kunii, Kristy G. Kuplast-Barr, Bin Gui, Sunaina P. Nayak, Elena Minissale, Kerren K. Swinger, Tim J. Wigle, Alvin Z. Lu, Danielle J. Blackwell, Christina R. Majer, Yue Ren, Ellen Bamberg, Mario Niepel, Jan-Rung Mo, William D. Church, Ahmed S. Mady, Jeff Song, Zacharenia A. Varsamis, Luke Utley, Patricia E. Rao, Timoty J. Mitchison, Kevin W. Kuntz, Victoria M. Richon, Kristen McEachern, Heike Keilhack
Publikováno v:
Cancer Research. 82:2154-2154
Targeting cytosolic nucleic acid sensing pathways to activate the Type I interferon (IFN) response is an emerging therapeutic strategy being explored in oncology. The PARP family consists of seventeen enzymes that regulate fundamental biological proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138b6edb388c9ff28b5c6026a9134c0a
https://doi.org/10.1158/1538-7445.am2022-2154
https://doi.org/10.1158/1538-7445.am2022-2154
Autor:
Tim J. Wigle, Luke Utley, Kevin Wayne Kuntz, Jeff Song, Jan-Rung Mo, W. David Church, Sunaina P. Nayak, Heike Keilhack, Yue Ren, Alvin Lu, Danielle J. Blackwell, Ryan Abo, Kaiko Kunii, Christina R. Majer, Ahmed S.A. Mady, Melissa M. Vasbinder, Ellen Bamberg, Kerren Kalai Swinger, Bin Gui, Victoria M. Richon, Mario Niepel, Patricia E. Rao, Kristy Kuplast-Barr, Jennifer R. Molina, Timothy J. Mitchison, Joseph M. Gozgit, Elena Minissale, Zacharenia A. Varsamis
Publikováno v:
Cancer cell. 39(9)
PARP7 is a monoPARP that catalyzes the transfer of single units of ADP-ribose onto substrates to change their function. Here, we identify PARP7 as a negative regulator of nucleic acid sensing in tumor cells. Inhibition of PARP7 restores type I interf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07edb791c59df419eedd1a9ffce03541
https://pubmed.ncbi.nlm.nih.gov/34375612
https://pubmed.ncbi.nlm.nih.gov/34375612
Autor:
Danielle J. Blackwell, Ryan Abo, Christina R. Majer, Jan-Rung Mo, Victoria M. Richon, Yue Ren, Alvin Lu, Luke Utley, Zacharenia A. Varsamis, Tim J. Wigle, Mario Niepel, Bin Gui, Kevin Wayne Kuntz, Jeff Song, Kerren Kalai Swinger, Kaiko Kunii, William Church, Sunaina P. Nayak, Joseph M. Gozgit, Melissa Vasbinder, Ellen Bamberg, Patricia E. Rao, Kristy Kuplast-Barr, Heike Keilhack, Timothy J. Mitchison
Publikováno v:
Cancer Research. 80:3405-3405
Targeting cytosolic nucleic acid sensing pathways and the Type I interferon (IFN) response is an emerging therapeutic strategy being explored in oncology. PARP7 is a member of the monoPARP class of enzymes, which catalyze the transfer of single units
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112e2524350629a13849861f971ffccc
https://doi.org/10.1158/1538-7445.am2020-3405
https://doi.org/10.1158/1538-7445.am2020-3405
Autor:
Patricia E. Rao, Danielle J. Blackwell, Ryan Abo, Kaiko Kunii, Kristy Kuplast-Barr, W. David Church, Victoria M. Richon, Heike Keilhack, Melissa M. Vasbinder, Jan-Rung Mo, Luke Utley, Ellen Bamberg, Mario Niepel, Zacharenia A. Varsamis, Yue Ren, Alvin Lu, Timothy J. Mitchison, Tim J. Wigle, Christina R. Majer, Kevin Wayne Kuntz, Jeff Song, Kerren Kalai Swinger, Joseph M. Gozgit, Bin Gui, Sunaina P. Nayak
Publikováno v:
Cancer Research. 80:DDT02-01
RBN-2397: A first-in-class PARP7 inhibitor targeting a newly discovered cancer vulnerability in stress-signaling pathways PARP7 is a monoPARP that catalyzes the transfer of single units of ADP-ribose onto substrates to change their function (MARylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::863abc28e5666d46a68f4a84fb89c594
https://doi.org/10.1158/1538-7445.am2020-ddt02-01
https://doi.org/10.1158/1538-7445.am2020-ddt02-01