Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sunaina Kiran Prabhu"'
Autor:
Liang Lin, Weston Kightlinger, Sunaina Kiran Prabhu, Adam J. Hockenberry, Chao Li, Lai-Xi Wang, Michael C. Jewett, Milan Mrksich
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 144-154 (2020)
Externí odkaz:
https://doaj.org/article/589e77929a724b96ba3469489df5b045
Autor:
Yongjun Sui, Jianping Li, Roushu Zhang, Sunaina Kiran Prabhu, Hanne Andersen, David Venzon, Anthony Cook, Renita Brown, Elyse Teow, Jason Velasco, Jack Greenhouse, Tammy Putman-Taylor, Tracey-Ann Campbell, Laurent Pessaint, Ian N. Moore, Laurel Lagenaur, Jim Talton, Matthew W. Breed, Josh Kramer, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Mark G. Lewis, Lai-Xi Wang, Jay A. Berzofsky
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have focused on systemic immunization, here we compared the protective efficacy of 2 adjuvanted subunit vaccines with spike protein S1: an intramuscularly primed/boos
Externí odkaz:
https://doaj.org/article/d56cb415c28b4c54afc3a16c9c73cf2f
Autor:
Kun Huang, Chao Li, Guanghui Zong, Sunaina Kiran Prabhu, Digantkumar G. Chapla, Kelley W. Moremen, Lai-Xi Wang
Publikováno v:
Bioorg Chem
Sulfation is a common modification of glycans and glycoproteins. Sulfated N-glycans have been identified in various glycoproteins and implicated for biological functions, but in vitro synthesis of structurally well-defined full length sulfated N-glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3bd464d020ce1e89e5c8e6206fc728
https://pubmed.ncbi.nlm.nih.gov/35939855
https://pubmed.ncbi.nlm.nih.gov/35939855
Autor:
Sunaina Kiran Prabhu, Michael C. Jewett, Liang Lin, Milan Mrksich, Lai-Xi Wang, Weston Kightlinger, Chao Li, Adam J. Hockenberry
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 144-154 (2020)
ACS Central Science
ACS Central Science
Protein glycosylation is a common post-translational modification that influences the functions and properties of proteins. Despite advances in methods to produce defined glycoproteins by chemoenzymatic elaboration of monosaccharides, the understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1a135395900150c42e54a39c2ae3fc
https://doaj.org/article/589e77929a724b96ba3469489df5b045
https://doaj.org/article/589e77929a724b96ba3469489df5b045
Publikováno v:
Chemistry
Monoclonal antibodies (mAbs) are one of the most rapidly growing drug classes used for the treatment of cancer, infectious and autoimmune diseases. Complement-dependent cytotoxicity (CDC) is one of the effector functions for antibodies to deplete tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b736c93a5166cd2a9d76ef470e5b58
https://europepmc.org/articles/PMC8930617/
https://europepmc.org/articles/PMC8930617/
Publikováno v:
ACS Chem Biol
Site-specific labeling and conjugation of antibodies are highly desirable for fundamental research and for developing more efficient diagnostic and therapeutic methods. We report here a general and robust chemoenzymatic method that permits a one-pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40145f60aab225906a2e2fb848ef4f3a
https://pubmed.ncbi.nlm.nih.gov/34569782
https://pubmed.ncbi.nlm.nih.gov/34569782
Publikováno v:
Chem Commun (Camb)
Glycosylation plays important roles in SARS-CoV-2 infection. We describe here a facile chemoenzymatic synthesis of core-fucosylated N-glycopeptides derived from the SARS-CoV-2 Spike protein and their binding with glycan-dependent neutralizing antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ae3e05b29f2d4e017e27a34746353b
https://pubmed.ncbi.nlm.nih.gov/34236361
https://pubmed.ncbi.nlm.nih.gov/34236361
Autor:
Roushu Zhang, Jason Velasco, Lai-Xi Wang, Jack Greenhouse, Laurent Pessaint, Kevin W. Bock, Bianca M. Nagata, Mahnaz Minai, Renita Brown, Jay A. Berzofsky, Yongjun Sui, Tammy Putman-Taylor, Hanne Leth Andersen, Mark G. Lewis, Jianping Li, David Venzon, Laurel A. Lagenaur, Ian N. Moore, Elyse Teow, Sunaina Kiran Prabhu, Matthew Breed, Josh Kramer, Jim Talton, Tracey-Ann Campbell, Anthony L. Cook
Publikováno v:
JCI Insight
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have focused on systemic immunization, here we compared the protective efficacy of 2 adjuvanted subunit vaccines with spike protein S1: an intramuscularly primed/boos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d4c707e5e5482f8f4eafe03d127ecf
http://europepmc.org/articles/PMC8262352
http://europepmc.org/articles/PMC8262352
Publikováno v:
Bioorg Med Chem
The conventional use of E. coli system for protein expression is limited to non-glycosylated proteins. While yeast, insect and mammalian systems are available to produce heterologous glycoproteins, developing an engineered E. coli-based glycosylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a51d15f8f18b8babc3aeabea70fcf3
https://pubmed.ncbi.nlm.nih.gov/33515919
https://pubmed.ncbi.nlm.nih.gov/33515919
Publikováno v:
Bioorg Med Chem
Core fucosylation is the attachment of an α-1,6-fucose moiety to the innermost N-acetyl glucosamine (GlcNAc) in N-glycans in mammalian systems. It plays a pivotal role in modulating the structural and biological functions of glycoproteins including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae1b693599f77b03e86e09274ed980d
https://doi.org/10.1016/j.bmc.2021.116243
https://doi.org/10.1016/j.bmc.2021.116243