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Akademický článek

Soft-capsule formulation of a re-esterified triglyceride omega-3 employing self-emulsifying technology and bioavailability evaluation in healthy volunteers

Autor: Gi Hyeong Sin, Sun Ho Hong, Yoon Tae Goo, Hyun Min Jung, Sangkil Lee, Young Wook Choi

Publikováno v: Heliyon, Vol 9, Iss 10, Pp e20376- (2023)

Despite the superior clinical efficacy of the re-esterified triglyceride (rTG) form compared to the ethylester form, few studies have been conducted on improving the bioavailability of the rTG form of omega-3 oil. The aim of study was to evaluate the

Externí odkaz: https://doaj.org/article/b25e62fc2acc41f68a4db8ba8c92c20b

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Akademický článek

Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design

Autor: Yoon Tae Goo, Sangkil Lee, Ji Yeh Choi, Min Song Kim, Gi Hyeong Sin, Sun Ho Hong, Chang Hyun Kim, Seh Hyon Song, Young Wook Choi

Publikováno v: Drug Delivery, Vol 29, Iss 1, Pp 2831-2845 (2022)

The lipophilicity of a peptide drug can be considerably increased by hydrophobic ion pairing with amphiphilic counterions for successful incorporation into lipid-based formulations. Herein, to enhance the oral absorption of insulin (INS), a self-micr

Externí odkaz: https://doaj.org/article/7f248a6afc39449aa2b08ca02e12c71a

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