Výsledky vyhledávání - "Sun-Oh Jeong"

Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia

Autor: Se-Ung Park, Hyun-Ock Pae, Young-Joon Surh, Hun Taeg Chung, Seong Hoon Park, Yeonsoo Joe, Sena Kim, Jaekyoon Shin, Sun Oh Jeong, Jin Kyung Kim

Publikováno v: Journal of Leukocyte Biology. 104:1003-1012

Endotoxin tolerance develops in the late phase of sepsis to protect cells from an early hyperinflammatory response. Nonetheless, because it induces an immunosuppressive environment, patients with sepsis in its late phase are affected by secondary inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2bb4a69009dcb2f9fcd8b54c8ed938
https://doi.org/10.1002/jlb.3a0317-106rrr

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Pterostilbene, an Active Constituent of Blueberries, Stimulates Nitric Oxide Production via Activation of Endothelial Nitric Oxide Synthase in Human Umbilical Vein Endothelial Cells

Autor: Hyun-Ock Pae, Seong Hoon Park, Hun-Teag Chung, Sun-Oh Jeong

Publikováno v: Plant Foods for Human Nutrition. 70:263-268

Endothelial dysfunction, a key process in development of cardiovascular diseases, is largely due to reduced nitric oxide (NO) derived from endothelial NO synthase (eNOS). Resveratrol has been reported to stimulate NO production via estrogen receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f5e56904e869f6f8a4663938a3bf68
https://doi.org/10.1007/s11130-015-0488-3

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Endoplasmic Reticulum Stress–Induced IRE1α Activation Mediates Cross-Talk of GSK-3β and XBP-1 To Regulate Inflammatory Cytokine Production

Autor: You-Sun Kim, Young-Joon Surh, Hun Taeg Chung, Sun Oh Jeong, Hyo Jeong Kim, Yeonsoo Joe, Stefan W. Ryter, Hyun-Ock Pae, Sena Kim

Publikováno v: The Journal of Immunology. 194:4498-4506

IL-1β and TNF-α are important proinflammatory cytokines that respond to mutated self-antigens of tissue damage and exogenous pathogens. The endoplasmic reticulum (ER) stress and unfolded protein responses are related to the induction of proinflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3814a34ef0cbccc18cf6c0947349b0
https://doi.org/10.4049/jimmunol.1401399

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Resveratrol analog piceatannol restores the palmitic acid-induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti-inflammatory and antioxidative heme oxygenase-1 in human endothelial cells

Autor: Ju Hwan Lee, Sun Oh Jeong, Seong Hoon Park, Yong Kwan Cheong, Hun Taeg Chung, Hyun Ock Pae, Yong Son

Publikováno v: Molecular Medicine Reports

Growing evidence suggests that the elevation of free fatty acids, including palmitic acid (PA), are associated with inflammation and oxidative stress, which may be involved in endothelial dysfunction, characterized by the reduced bioavailability of n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4412790bbbbe665d658d301a8dab7fc7
https://doi.org/10.3892/mmr.2015.3553

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IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production

Autor: Hyun-Ock Pae, Seul-Ki Kim, Hun Taeg Chung, Sun Oh Jeong, Jamal Uddin, Yeonsoo Joe, Stefan W. Ryter

Publikováno v: Cellular and Molecular Immunology

The immunoresponsive gene 1 (IRG1) protein has crucial functions in embryonic implantation and neurodegeneration. IRG1 promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species (ROS). The cytoprotective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e031e7b8ae86b402f393b6dcf14059d
http://europepmc.org/articles/PMC4786624

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Both nitric oxide and nitrite prevent homocysteine-induced endoplasmic reticulum stress and subsequent apoptosis via cGMP-dependent pathway in neuronal cells

Autor: Sung Hun Kim, Hyun-Ock Pae, Ju Hwan Lee, Hun-Taeg Chung, Seung Won Choi, Sun-Oh Jeong, Yong Son, Yong-Kwan Cheong

Publikováno v: Biochemical and biophysical research communications. 493(1)

Growing evidence indicates that endoplasmic reticulum (ER) stress and/or ER stress-mediated apoptosis may play a role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease. The present study investigated the effects of non-cyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af4468883c880f8a445a578d5902db4
https://pubmed.ncbi.nlm.nih.gov/28917840

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Carbon Monoxide Protects against Hepatic Ischemia/Reperfusion Injury via ROS-Dependent Akt Signaling and Inhibition of Glycogen Synthase Kinase 3β

Autor: Jin Sun Kong, Hun Taeg Chung, Stefan W. Ryter, Gyeong Jae Cho, Yeonsoo Joe, Sun-Oh Jeong, Hyo Jeong Kim

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2013 (2013)
Oxidative Medicine and Cellular Longevity

Carbon monoxide (CO) may exert important roles in physiological and pathophysiological states through the regulation of cellular signaling pathways. CO can protect organ tissues from ischemia/reperfusion (I/R) injury by modulating intracellular redox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0080d83c1aaef39eb058a38abf02a38a
https://doi.org/10.1155/2013/306421

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