Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sun-Kyoung Kang"'
Autor:
Juin Park, Sun Kyoung Kang, Woo Sun Kwon, Inhye Jeong, Tae Soo Kim, Seo Young Yu, Sang Woo Cho, Hyun Cheol Chung, Sun Young Rha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Trastuzumab is used to treat HER2-amplified metastatic gastric cancer; however, most patients become trastuzumab-resistant within a year. Knowledge of the mechanisms underlying trastuzumab resistance is required to overcome this limitation.
Externí odkaz:
https://doaj.org/article/9c8ac4ba3ae74cd38342c478ae5a2715
Publikováno v:
Applied Sciences, Vol 12, Iss 23, p 12457 (2022)
We propose a study to predict health abnormalities by analyzing body temperature and the heart rate variability parameters of pulse waves. The research method firstly selects fever by applying a deep learning model to thermal images, and secondly, ex
Externí odkaz:
https://doaj.org/article/14c65064818648f3a81ee230f29efab4
Autor:
Sun-Kyoung Kang
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 18:1582-1585
Recently, research on methods to improve upon the security vulnerability of password based authentication is being actively conducted. Research on how to use real-time biometric recognition is also actively underway. The system development of Public
Publikováno v:
Cancer Research. 82:5700-5700
Epigenetic dysregulation is a common characteristic of cancers, including gastric cancer (GC), which contributes to the development and progression of GC. BRD4 is one of the leaders for epigenetic regulation and is known to regulate the expression of
Autor:
Eun Yi Cho, Hyeon Joo Kim, Byeonghak Moon, Yerin Jo, Jinsu Bae, Ga Ram Kim, Yong-Chul Kim, Sun Kyoung Kang, Woo Sun Kwon, Tae Soo Kim, Sun Young Rha, Hyun Cheol Chung
Publikováno v:
Cancer Research. 82:5445-5445
Transglutaminase 2 (TGase 2) is a multi-functional, ubiquitous enzyme that is important for various cellular processes, including apoptosis, development, differentiation, wound healing, and angiogenesis. TGase2 plays important roles in the pathogenes
Autor:
Hyun Cheol Chung, Juin Park, Sun Young Rha, Tae Soo Kim, Hyun Joo Bae, Sun Kyoung Kang, Kyoo Hyun Kim, Seo Young Yu, Woo Sun Kwon, Sejung Park, Jihyun Hwang
Publikováno v:
Cellular oncology (Dordrecht). 44(6)
Epigenetic dysregulation is a common characteristic of cancers, including gastric cancer (GC), and contributes to cancer development and progression. Although the efficacy of BET (an epigenetic regulator) inhibition has been demonstrated in various c
Autor:
sun Kyoung Kang
Publikováno v:
Research Institute for Life and Culture Sogang University. 51:219-238
Autor:
Woo Sun Kwon, Hyun Cheol Chung, Sun Young Rha, Jingmin Che, Sun Kyoung Kang, Tae Soo Kim, Hyun Joo Bae
Publikováno v:
Genomics & Informatics
BET inhibitor, as an epigenetic regulator inhibitor, reduces the expression of oncogenes such as Myc and Bcl-2, which affects cancer growth and development. However, it has modest activity because of the narrow therapeutic index. Therefore, combinati
Autor:
Jihyun Hwang, Juin Park, Inhye Jeong, Jingmin Che, Sun Young Rha, Hyun Cheol Chung, Woo Sun Kwon, Tae Soo Kim, Hyun Joo Bae, Sun Kyoung Kang
Publikováno v:
Cancer Research. 81:2055-2055
One of the many causes of cancer is a dysfunction of the DNA damage repair (DDR) pathway. Cancers with alterations in homologous recombination (HR) genes are known to be increased the sensitivity of PARP inhibitors and genomic instability. Besides, c
Autor:
Jihyun Hwang, Sun Young Rha, Inhye Jeong, Tae Soo Kim, Woo Sun Kwon, Sun Kyoung Kang, Hyun Cheol Chung, Seo Young Yu, Juin Park
Publikováno v:
Cancer Research. 81:1090-1090
HER2 is amplified in 7% to 20% of gastric cancer (GC) and is associated with poor clinical outcome. Trastuzumab, HER2-targeting antibody, has already been successfully employed for the treatment of HER2 amplified metastatic GC patients. However, most