Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sun-Jung Cho"'
Publikováno v:
Stem Cell Research, Vol 75, Iss , Pp 103303- (2024)
Human induced pluripotent stem cells (hiPSCs) have potential use in regerenrative medicine for disease modeling and drug screening studies. The AAVS1 locus has been validated as a stable transgene expression and safe genomic location. Therefore, we i
Externí odkaz:
https://doaj.org/article/a9ee9b55219d42c9a781ed63febe488c
Autor:
Sun-Jung Cho, Sang-Moon Yun, Chulman Jo, Jihyun Jeong, Moon Ho Park, Changsu Han, Young Ho Koh
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224941 (2019)
Notch signaling is an evolutionarily conserved pathway that regulates cell-cell interactions through binding of Notch family receptors to their cognate ligands. Notch signaling has an essential role in vascular development and angiogenesis. Recent st
Externí odkaz:
https://doaj.org/article/970b543f98114d78be0c4684641f1d4f
Publikováno v:
BMB Reports, Vol 45, Iss 4, Pp 227-232 (2012)
In vertebrates, there are two variants of eukaryotic peptideelongation factor 1A (eEF1A; formerly eEF-1α), eEF1A1 andeEF1A2, which have three well-conserved domains (DI, DII,and DIII). In neurons, eEF1A1 is the embryonic type, which isexpressed duri
Externí odkaz:
https://doaj.org/article/7e36d5169c2d42e6a105b9b8b28daf36
Autor:
Jung Hyun Park, Sun-Jung Cho, Chulman Jo, Moon Ho Park, Changsu Han, Eun-Joo Kim, Gi Yeong Huh, Young Ho Koh
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 5; Pages: 827
Tissue inhibitor of metalloproteinase-3 (TIMP-3) is a component of the extracellular environment and is suggested to play an indirect role in regulating Aβ production and the pathophysiology of Aβ deposition in brains. However, studies on the amoun
Autor:
Sun-Jung Cho, Jung Hyun Park, Young Ho Koh, Mun-Jin Kwon, Ji-Young Choi, Hye-Kyung Lee, Chulman Jo
Publikováno v:
Biochemical and Biophysical Research Communications
Coronavirus disease 2019 (COVID-19) is a worldwide pandemic. It has a high transmission rate among humans, and is a threat to global public health. However, there are no effective prophylactics or therapeutics available. It is necessary to identify v
Autor:
Sun Jung Cho, Changsu Han, Chulman Jo, Ji-Young Choi, Moon Ho Park, Gi Yeong Huh, Eun-Joo Kim, Young Ho Koh, Sang Moon Yun, Jung Hyun Park
Publikováno v:
Journal of neuropathology and experimental neurology. 79(5)
N-cadherin is a synaptic adhesion molecule stabilizing synaptic cell structure and function. Cleavage of N-cadherin by γ-secretase produces a C-terminal fragment, which is increased in the brains of Alzheimer disease (AD) patients. Here, we investig
Autor:
Moon Ho Park, Sang Moon Yun, Young Ho Koh, Chulman Jo, Sun Jung Cho, Changsu Han, Jihyun Jeong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0224941 (2019)
PLoS ONE, Vol 14, Iss 11, p e0224941 (2019)
Notch signaling is an evolutionarily conserved pathway that regulates cell-cell interactions through binding of Notch family receptors to their cognate ligands. Notch signaling has an essential role in vascular development and angiogenesis. Recent st
Publikováno v:
Archives of Gerontology and Geriatrics. 87:103995
Introduction Beta-amyloid is considered to be a pathophysiological marker in Alzheimer's disease (AD). Soluble amyloid precursor proteins (sAPPs) –α (sAPPα) and –β (sAPPβ), which are the byproducts of non-amyloidogenic and amyloidogenic proce
Autor:
Rudolph E. Tanzi, Hyun Joung Lim, Sangmee Ahn Jo, Neil W. Kowall, Daehoon Lee, Sun-Jung Cho, Moon Ho Park, JiWoong Seok, Hoon Ryu, Changsu Han, Young Ho Koh, Chulman Jo
Alzheimer’s disease (AD) is characterized by amyloid plaques and pathologic cerebrovascular remodeling. Cerebrovascular abnormalities may contribute to the pathology of AD, but the molecular mechanisms are not fully understood. In this study, we ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ad47ef82d0f9e1b746dc243b1b5ba8
https://doi.org/10.1101/430140
https://doi.org/10.1101/430140
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Alzheimer’s disease (AD) is a major cause of dementia. Growing evidence suggests that dysregulation of autophagy, a cellular mechanism essential for self-digestion of damaged proteins and organelles, is involved in neurological degenerative disease