Výsledky vyhledávání - "Sun-Hyung Ha"

Akademický článek

4-O-Carboxymethylascochlorin Inhibits Expression Levels of on Inflammation-Related Cytokines and Matrix Metalloproteinase-9 Through NF–κB/MAPK/TLR4 Signaling Pathway in LPS-Activated RAW264.7 Cells

Autor: Junyoung Park, Sun-Hyung Ha, Fukushi Abekura, Hakseong Lim, Juni Magae, Ki-Tae Ha, Tae-Wook Chung, Young-Chae Chang, Young-Choon Lee, Eunyong Chung, Jiyeon Ku, Cheorl-Ho Kim

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Toll-like receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) are known to play important roles in inflammatory diseases such as arteriosclerosis and plaque instability. The purpose of this study was to perform the effect of 4-O-carboxymethylasc

Externí odkaz: https://doaj.org/article/1a4376c889dc4fdea87ebb9f88650be2

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Akademický článek

Induction of Apoptosis and Antitumor Activity of Eel Skin Mucus, Containing Lactose-Binding Molecules, on Human Leukemic K562 Cells

Autor: Choong-Hwan Kwak, Sook-Hyun Lee, Sung-Kyun Lee, Sun-Hyung Ha, Seok-Jong Suh, Kyung-Min Kwon, Tae-Wook Chung, Ki-Tae Ha, Young-Chae Chang, Young-Choon Lee, Dong-Soo Kim, Hyeun-Wook Chang, Cheorl-Ho Kim

Publikováno v: Marine Drugs, Vol 13, Iss 6, Pp 3936-3949 (2015)

For innate immune defense, lower animals such as fish and amphibian are covered with skin mucus, which acts as both a mechanical and biochemical barrier. Although several mucus sources have been isolated and studied for their biochemical and immunolo

Externí odkaz: https://doaj.org/article/e08fddeb3db5431a81653746ce03ad07

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Akademický článek

Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages.

Autor: Jun-Young Park, Tae-Wook Chung, Yun-Jeong Jeong, Choong-Hwan Kwak, Sun-Hyung Ha, Kyung-Min Kwon, Fukushi Abekura, Seung-Hak Cho, Young-Choon Lee, Ki-Tae Ha, Junji Magae, Young-Chae Chang, Cheorl-Ho Kim

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171322 (2017)

The natural fungal compound ascofuranone (5-chloro-3-[(2E,6E)-7-[(2S)-5,5-dimethyl-4-oxo-tetrahydrofuran-2-yl]-3-methyl-octa-2,6-dienyl]-2,4-dihydroxy-6-methyl-benzaldehyde, MW 420.93) (AF) isolated from Ascochyta viciae has been known to promote cel

Externí odkaz: https://doaj.org/article/ff7d165b9f034b1998a9e9249e1e09d7

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Akademický článek

Jellyfish extract induces apoptotic cell death through the p38 pathway and cell cycle arrest in chronic myelogenous leukemia K562 cells

Autor: Sun-Hyung Ha, Fansi Jin, Choong-Hwan Kwak, Fukushi Abekura, Jun-Young Park, Nam Gyu Park, Young-Chae Chang, Young-Choon Lee, Tae-Wook Chung, Ki-Tae Ha, Jong-Keun Son, Hyeun Wook Chang, Cheorl-Ho Kim

Publikováno v: PeerJ, Vol 5, p e2895 (2017)

Jellyfish species are widely distributed in the world’s oceans, and their population is rapidly increasing. Jellyfish extracts have several biological functions, such as cytotoxic, anti-microbial, and antioxidant activities in cells and organisms.

Externí odkaz: https://doaj.org/article/b77b1321f34548409280b2e3767c71df

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Akademický článek

Exogenous and Endogeneous Disialosyl Ganglioside GD1b Induces Apoptosis of MCF-7 Human Breast Cancer Cells

Autor: Sun-Hyung Ha, Ji-Min Lee, Kyung-Min Kwon, Choong-Hwan Kwak, Fukushi Abekura, Jun-Young Park, Seung-Hak Cho, Kichoon Lee, Young-Chae Chang, Young-Choon Lee, Hee-Jung Choi, Tae-Wook Chung, Ki-Tae Ha, Hyeun-Wook Chang, Cheorl-Ho Kim

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 5, p 652 (2016)

Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in human breast cancer MCF-7 cells using exogenous treatment of the cells with GD1b and endogen

Externí odkaz: https://doaj.org/article/28eba6c44a53426a8331e64977a56ba4

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Mycobacterium tuberculosis–Secreted Protein, ESAT-6, Inhibits Lipopolysaccharide-Induced MMP-9 Expression and Inflammation Through NF-κB and MAPK Signaling in RAW 264.7 Macrophage Cells

Autor: Sun-Hyung Ha, Young-Choon Lee, Hyunju Choi, Cheorl-Ho Kim, Fukushi Abekura, Jun-Young Park, Jeong-Ran Kim

Publikováno v: Inflammation. 43:54-65

20pt?>Mycobacterium tuberculosis (Mtb) is a pathogenic bacterium that causes contagious tuberculosis (TB). Recently, Mtb-secreted proteins have been considered virulence factors and candidates for drugs and vaccines. Among these proteins, 6-kDa early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d9bb73bfcff8f36189434422dcb3c0
https://doi.org/10.1007/s10753-019-01087-x

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Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP‐9 gene expression via NF‐kB signaling pathway

Autor: Jong-Suk Kim, Jun-Young Park, Tae-Wook Chung, Seung-Hak Cho, Cheorl-Ho Kim, Fukushi Abekura, Young-Choon Lee, Kyung-Min Kwon, Hyeun Wook Chang, Ki-Tae Ha, Sun-Hyung Ha

Publikováno v: Journal of Cellular Biochemistry. 120:9810-9819

A water-soluble saponin, Esculentoside H (EsH), 3-O-(O-β-d-glucopyranosyl-(1→4)-β-d-xylopyranosyl)-28-β-d-glucopyranosylphytolaccagenin has been isolated and purified from the root extract of perennial plant Phytolacca esculenta. EsH is known to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c38fc3a88c451a96107defedd50b15
https://doi.org/10.1002/jcb.28261

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Abstract 1626: PMC309, a highly selective anti-VISTA antibody enhances T cell activation through blocking the interaction of T cells and myeloid derived suppressor cells (MDSC)

Autor: Sun Hyung Ha, Beom Yong Park, Jin-San Yoo, Nu Ri Kang, Hyun Sun Park, Jin Yong An, Cheon Ho Park, Byun Sang Soon, Hye Rim Han, Eun-Ah Lee, Weon Sup Lee

Publikováno v: Cancer Research. 81:1626-1626

TME (tumor microenvironment) consists of blood & lymphatic vessels, stromal cells, and immune cells such as lymphocytes, macrophages, and antigen-presenting cells (APC). Cellular interactions among various immune cell types within TME regulate tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85a5abfae981c275f2577c27b713b8a5
https://doi.org/10.1158/1538-7445.am2021-1626

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Sialyllactose suppresses angiogenesis by inhibiting VEGFR-2 activation, and tumor progression

Autor: Hee-Jung Choi, Fukushi Abekura, Sun Hyung Ha, Tae-Wook Chung, Keuk-Jun Kim, Choong Hwan Kwak, Ki-Tae Ha, Cheorl Ho Kim, Eun-Young Kim, Se Bok Jang, Seok Jo Kim

Publikováno v: Oncotarget

// Tae-Wook Chung 1 , Eun-Young Kim 1, 2 , Seok-Jo Kim 3 , Hee-Jung Choi 1 , Se Bok Jang 4 , Keuk-Jun Kim 5 , Sun-Hyung Ha 3 , Fukushi Abekura 3 , Choong-Hwan Kwak 3 , Cheorl-Ho Kim 3 and Ki-Tae Ha 1, 2 1 School of Korean Medicine, Healthy Aging Kore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837aa42f7e421a281a2f9ccdd87f88b8
https://doi.org/10.18632/oncotarget.16192

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Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells

Autor: Young-Choon Lee, Tae-Wook Chung, Kyung-Min Kwon, Hee-Jung Choi, Cheorl-Ho Kim, Seung-Hak Cho, Kyung-Woon Kim, Choong-Hwan Kwak, Sun-Hyung Ha, Moon-Jo Lee, Ki-Tae Ha

Publikováno v: International Journal of Biological Sciences

The disialoganglioside GD3 has been considered to be involved in tumor progression or suppression in various tumor cells. However, the significance of the biological functions of GD3 in breast cancer cells is still controversial. This prompted us to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206ebe84f143ee308f99ba9341bea377
https://doi.org/10.7150/ijbs.16903

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