Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sun-Gou Ji"'
Autor:
Bryan R. Gorman, Sun-Gou Ji, Michael Francis, Anoop K. Sendamarai, Yunling Shi, Poornima Devineni, Uma Saxena, Elizabeth Partan, Andrea K. DeVito, Jinyoung Byun, Younghun Han, Xiangjun Xiao, Don D. Sin, Wim Timens, Jennifer Moser, Sumitra Muralidhar, Rachel Ramoni, Rayjean J. Hung, James D. McKay, Yohan Bossé, Ryan Sun, Christopher I. Amos, VA Million Veteran Program, Saiju Pyarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and smoking behavioral susceptibility remain
Externí odkaz:
https://doaj.org/article/dac86f32ac504f5bbdb7376d6931934e
Autor:
Jeremy Chang, Marcus Soliai, Connor Barnhill, Lyndsay Smith, Arun Mathew, Alexander Apostolov, Ben Dulken, Aleksandr Petukhov, Ananth Sridhar, Caroline Gorvin, Christoph Lange, Russ Altman, Scott Adler, Mary Scott Roberts, Jonathan Fox, Sun-Gou Ji
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101058- (2024)
Externí odkaz:
https://doaj.org/article/8a79c8b841824963ad8ada9ff47908e8
Autor:
John Concato, Timothy J. O'Leary, Mary Brophy, Lakshmi Radhakrishnan, Jie Huang, Purushotham Karnam, VA Million Veteran Program, Sun-Gou Ji, Haley Hunter-Zinck, Saiju Pyarajan, Man Li, Yunling Shi, Xin Gong, Jennifer Moser, Ronald M. Przygodzki, Philip S. Tsao, Elizabeth R. Hauser, Sumitra Muralidhar, Joel Gelernter, Paul Hsieh, John Michael Gaziano, Ning Sun, Poornima Devineni, Donald E. Humphries, Christopher J. O'Donnell, Hongyu Zhao, Teresa Webster, Themistocles L. Assimes, Grant D. Huang, Jeanette Schmidt, Andrew Liem, Cuiping Pan, Bryan R Gorman
Publikováno v:
Am J Hum Genet
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA), aims to collect biosamples with consent from at least one million veterans. Presently, blood samples have been collected from over 800,000 enrolled participants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6551f00af2013674a1d49a2268eea172
https://doi.org/10.1016/j.ajhg.2020.03.004
https://doi.org/10.1016/j.ajhg.2020.03.004
Autor:
Donald E. Humphries, Tim Assimes, Yunling Shi, Joel Gelernter, John Michael Gaziano, Liem A, Mary Brophy, Karnam P, Cuiping Pan, Jie Huang, Teresa Webster, Saiju Pyarajan, Man Li, Sun-Gou Ji, Jeanette Schmidt, Timothy J. O'Leary, Jennifer Moser, Ning Sun, Grant D. Huang, Sumitra Muralidhar, Radhakrishnan L, Elizabeth R. Hauser, P.S. Tsao, Paul Hsieh, Poornima Devineni, Ronald M. Przygodzki, Christopher J. O'Donnell, Hongyu Zhao, John Concato, Haley Hunter-Zinck, Gorman Br
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA), aims to collect consented biosamples from at least one million Veterans. Presently, blood samples have been collected from over 800,000 enrolled participants. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e264d50662c6a186744fd9c7e1ae0d
https://doi.org/10.1101/2020.01.06.896613
https://doi.org/10.1101/2020.01.06.896613
Autor:
Christopher L. Bowlus, Sören Mucha, Piotr Milkiewicz, Jennifer G. Sambrook, Michael P. Manns, Peter R. Durie, Daniel J. Gaffney, Catalina Coltescu, Konstantinos N. Lazaridis, David Ellinghaus, Daniel Gotthardt, George F. Mells, Espen Melum, Joseph A. Odin, Mattias Laudes, Cisca Wijmenga, Kris V. Kowdley, Annarosa Floreani, Tejas S. Shah, Richard Sandford, Erik M. Schlicht, Kirsten Muri Boberg, Javier Gutierrez-Achury, Felix Braun, Martina Sterneck, Carl A. Anderson, Tom H. Karlsen, Andre Franke, Velimir A. Luketic, Brijesh Srivastava, Aliya Gulamhusein, Elizabeth C. Goode, Kelly Spiess, Gunnar Jacobs, Olivier Chazouillères, Wolfgang Lieb, Tobias Müller, Andreas Teufel, Trine Folseraas, Roger W. Chapman, Hanns-Ulrich Marschall, David J. Roberts, Christoph Schramm, Sun-Gou Ji, Albert Parés, Mariza de Andrade, Stefan Schreiber, Elizabeth J. Atkinson, Kimmo Kontula, Pietro Invernizzi, Simon M. Rushbrook, Luke Jostins, Carmel Moore, Naga Chalasani, Jimmy Z. Liu, Brian D. Juran, Willem H. Ouwehand, Graeme J.M. Alexander, John E. Eaton, Gideon M. Hirschfield, Natsuhiko Kumasaka, Martti Färkkilä, Annika Bergquist, Kapil B. Chopra, John Danesh, Bertus Eksteen, Tobias J. Weismüller, Rinse K. Weersma, Ulrich Beuers, Severine Vermeire
Publikováno v:
Nature genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature genetics, 49(2), 269-273. Nature Publishing Group
Nature Genetics, 49(2), 269-273. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature genetics, 49(2), 269-273. Nature Publishing Group
Nature Genetics, 49(2), 269-273. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; similar to 75% of patients have comorbid inflammatory bowel disease (IBD). We undertook the largest genome-wide association study of PSC (4,796 case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e616bfb58aa70eae7a4f7dc8d1af15da
http://europepmc.org/articles/PMC5540332
http://europepmc.org/articles/PMC5540332
Autor:
Mette Vesterhus, Simon M. Rushbrook, Richard Sandford, Kate D. Lynch, Douglas Thorburn, George F. Mells, William Gelson, Edit Castren, Gideon M. Hirschfield, Palak J. Trivedi, Roger W. Chapman, Sun-Gou Ji, M. Aldersley, Mark Hudson, Michael A. Heneghan, Andrew Bathgate, Graeme J.M. Alexander, Brijesh Srivastava, Martine Walmsley, Carl A. Anderson, Tom H. Karlsen, Allan Clark, Elizabeth C. Goode, Kelly Spiess
Publikováno v:
Hepatology (Baltimore, Md.)
We sought to identify factors that are predictive of liver transplantation or death in patients with primary sclerosing cholangitis (PSC), and to develop and validate a contemporaneous risk score for use in a real-world clinical setting. Analyzing da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009bc10d71818fe7136a6946aee51c25
https://ora.ox.ac.uk/objects/uuid:2ce133cc-7d74-4380-bf6b-688baf54520b
https://ora.ox.ac.uk/objects/uuid:2ce133cc-7d74-4380-bf6b-688baf54520b
Autor:
Milos Popovic, Sun-Gou Ji, Yang Li, Peter Komar, Kaushik Ghose, James S. Spencer, Amit Jain, V. Arsenijevic, Alexey Dolgoborodov, John Browning, Jelena Nadj, Berke C. Toptas, Andrew L Stachyra, Vladimir Semenyuk, Iosif Spulber, Irina Glotova, Wan-Ping Lee, Bjoern Pollex, Deniz Kural, Lizao Li, Maria C. Suciu, Ivan E. Johnson, Morten Källberg, Gulfem Demir, Goran Rakocevic
Publikováno v:
Nature genetics. 51(2)
The human reference genome serves as the foundation for genomics by providing a scaffold for sequencing read alignment, but currently only reflects a single consensus haplotype, impairing read alignment and downstream analysis accuracy. Reference gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a3033e177dd5de0209ea7507e12dac
https://pubmed.ncbi.nlm.nih.gov/30643257
https://pubmed.ncbi.nlm.nih.gov/30643257
Autor:
Natalie J. Prescott, Holm H. Uhlig, Alison Simmons, William G. Newman, Loukas Moutsianas, David C. Wilson, Sun-Gou Ji, John C. Mansfield, Christopher J. Hawkey, Graham A. Heap, Cathryn Edwards, Charlie W. Lees, Javier Gutierrez-Achury, James Lee, Nicholas A. Kennedy, Christopher A. Lamb, Jeffrey C. Barrett, Craig Mowat, Christopher G. Mathew, Jack Satsangi, Yang Luo, Daniel L. Rice, Carl A. Anderson, Paul Henderson, Ailsa Hart, Jeremy D. Sanderson, Tariq Ahmad, Elaine R. Nimmo, Mark Tremelling, Luke Jostins, Miles Parkes, Katrina M. de Lange
Publikováno v:
de Lange, K M, Moutsianas, L, James C. Lee, Lamb, C A, Luo, Y, Kennedy, N A, Jostins, L, Rice, D L, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, E R, Edwards, C, Henderson, P, Mowat, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, D C, Tremelling, M, Hart, A, Mathew, C G, Newman, W, Parkes, M, Lees, C W, Uhlig, H, Hawkey, C, Prescott, N J, Ahmad, T, Mansfield, J C, Anderson, C A & Barrett, J C 2017, ' Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. ', Nature Genetics, vol. 49, pp. 256–261 . https://doi.org/10.1038/ng.3760
de Lange, K M, Moutsianas, L, Lee, J C, Lamb, C A, Luo, Y, Kennedy, N A, Jostins, L, Rice, D L, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, E R, Edwards, C, Henderson, P, Mowatt, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, D C, Tremelling, M, Hart, A, Matthew, C G, Newman, W G, Parkes, M, Lees, C W, Uhlig, H, Hawkey, C, Prescott, N J, Ahmad, T, Mansfield, J C, Anderson, C A & Barrett, J C 2017, ' Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease ', Nature Genetics, vol. 49, no. 2, pp. 256–261 . https://doi.org/10.1038/ng.3760
Nature genetics
de Lange, K M, Moutsianas, L, Lee, J C, Lamb, C A, Luo, Y, Kennedy, N A, Jostins, L, Rice, D L, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, E R, Edwards, C, Henderson, P, Mowat, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, D C, Tremelling, M, Hart, A, Mathew, C G, Newman, W G, Parkes, M, Lees, C W, Uhlig, H, Hawkey, C, Prescott, N J, Ahmad, T, Mansfield, J C, Anderson, C A & Barrett, J C 2017, ' Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease ', Nature Genetics, vol. 49, no. 2, pp. 256-261 . https://doi.org/10.1038/ng.3760
de Lange, K M, Moutsianas, L, Lee, J C, Lamb, C A, Luo, Y, Kennedy, N A, Jostins, L, Rice, D L, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, E R, Edwards, C, Henderson, P, Mowatt, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, D C, Tremelling, M, Hart, A, Matthew, C G, Newman, W G, Parkes, M, Lees, C W, Uhlig, H, Hawkey, C, Prescott, N J, Ahmad, T, Mansfield, J C, Anderson, C A & Barrett, J C 2017, ' Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease ', Nature Genetics, vol. 49, no. 2, pp. 256–261 . https://doi.org/10.1038/ng.3760
Nature genetics
de Lange, K M, Moutsianas, L, Lee, J C, Lamb, C A, Luo, Y, Kennedy, N A, Jostins, L, Rice, D L, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, E R, Edwards, C, Henderson, P, Mowat, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, D C, Tremelling, M, Hart, A, Mathew, C G, Newman, W G, Parkes, M, Lees, C W, Uhlig, H, Hawkey, C, Prescott, N J, Ahmad, T, Mansfield, J C, Anderson, C A & Barrett, J C 2017, ' Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease ', Nature Genetics, vol. 49, no. 2, pp. 256-261 . https://doi.org/10.1038/ng.3760
Genetic association studies have identified 215 risk loci for inflammatory bowel disease, thereby uncovering fundamental aspects of its molecular biology. We performed a genome-wide association study of 25,305 individuals and conducted a meta-analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9aa2a61e5e4729a3800e31b8cb129e0
https://doi.org/10.1038/ng.3760
https://doi.org/10.1038/ng.3760
Autor:
Graham A. Heap, James Lee, Nicholas A. Kennedy, Cathryn Edwards, Ailsa Hart, Daniel L. Rice, Javier Gutierrez-Achury, Christopher J. Hawkey, Jeremy D. Sanderson, Luke Jostins, Miles Parkes, Katrina M. de Lange, Mark Tremelling, David C. Wilson, Jeffrey C. Barrett, Carl A. Anderson, William G. Newman, Sun-Gou Ji, Elaine R. Nimmo, Paul Henderson, Natalie J. Prescott, Jack Satsangi, Christopher G. Mathew, Loukas Moutsianas, Yang Luo, Charlie W. Lees, Alison Simmons, Tariq Ahmad, Holm H. Uhlig, John C. Mansfield, Craig Mowat, Christopher A. Lamb
Genetic association studies have identified 210 risk loci for inflammatory bowel disease1–7, which have revealed fundamental aspects of the molecular biology of the disease, including the roles of autophagy and Th17 cell signaling and development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700dc483893cae56ee720e56c1510179
https://doi.org/10.1101/058255
https://doi.org/10.1101/058255
Autor:
Junhyeok Go, Insuk Lee, Sunmo Yang, Hye Jin Kim, Chan Yeong Kim, Sohyun Hwang, Sang Sun Yoon, Hanhae Kim, Ara Cho, Sun-Gou Ji
Publikováno v:
SCIENTIFIC REPORTS(6)
Scientific Reports
Scientific Reports
Pseudomonas aeruginosa is a Gram-negative bacterium of clinical significance. Although the genome of PAO1, a prototype strain of P. aeruginosa, has been extensively studied, approximately one-third of the functional genome remains unknown. With the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ed4e68c9a4b33d9235343f002a58b4