Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Sun Young Jang"'
Autor:
Charm Kim, Jin Hwan Park, Yeon Jeong Choi, Hyung Oh Jun, Jin Kwon Chung, Tae Kwann Park, Jin Sook Yoon, Jae Wook Yang, Sun Young Jang
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionBruton’s tyrosine kinase (BTK) and interleukin (IL)-2 Inducible T-cell Kinase (ITK) inhibitors have anti-inflammatory properties. We investigated the therapeutic effect of ibrutinib, an orally bioavailable BTK/ITK inhibitor, in a mouse
Externí odkaz:
https://doaj.org/article/bc38b2e305fa46d38ddee8fc57968fb7
Publikováno v:
Endocrinology and Metabolism, Vol 38, Iss 6, Pp 739-749 (2023)
Background Phospholipase C-γ (PLC-γ) plays a crucial role in immune responses and is related to the pathogenesis of various inflammatory disorders. In this study, we investigated the role of PLC-γ and the therapeutic effect of the PLC-specific inh
Externí odkaz:
https://doaj.org/article/d1d6633a0dff4d5280c50faac8b5ec91
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Graves’ orbitopathy (GO) is a complex autoimmune disorder of the orbit that causes the eye to appear disfigured. GO is typically associated with Graves’ disease, an inflammatory autoimmune condition that is caused by thyrotropin receptor autoanti
Externí odkaz:
https://doaj.org/article/c8e28873d0c049c9ac7ee98ecc5481a6
Autor:
Joo-Yun Byun, Yi T. Koh, Sun Young Jang, Jennifer W. Witcher, Jason R. Chan, Anna Pustilnik, Mark J. Daniels, Young Hoon Kim, Kwee Hyun Suh, Matthew D. Linnik, Young-Mi Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The selective Bruton tyrosine kinase (BTK) inhibitor poseltinib has been shown to inhibit the BCR signal transduction pathway and cytokine production in B cells (Park et al. Arthritis Res. Ther. 18, 91, https://doi.org/10.1186/s13075-016-098
Externí odkaz:
https://doaj.org/article/f84752f1ec4c42a4a963b56dd9003005
Autor:
Sun Young Jang, Jinjoo Kim, Jung Tak Park, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa, Eun Jig Lee, Jin Sook Yoon
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Periostin is a matricellular protein that is ubiquitously expressed in normal human tissues and is involved in pathologic mechanism of chronic inflammatory and fibrotic disease. In this study we investigate periostin in the pathogenesis of Graves’
Externí odkaz:
https://doaj.org/article/bf2fae0e4d4b40a28d57e73eef837a6e
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Purpose Bruton’s tyrosine kinase (BTK) is an essential protein in B-cell antigen receptor (BCR) signaling pathway and is known to be related to pathogenetic effect on B-cell related malignancies and various autoimmune diseases. In this study, we in
Externí odkaz:
https://doaj.org/article/3c1cc627035b4af081db684ae695179e
Autor:
Yeon Jeong Choi, Charm Kim, Eun Woo Choi, Seung Hun Lee, Min Kyung Chae, Hyung Oh Jun, Bo-Yeon Kim, Jin Sook Yoon, Sun Young Jang
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0270416 (2022)
To investigate the role of microRNA (miR)-155 in inflammation in an in-vitro model of Graves' orbitopathy (GO). The expression levels of miR-155 were compared between GO and non-GO orbital tissues. The effects of inflammatory stimulation of interleuk
Externí odkaz:
https://doaj.org/article/0ab39ec0e5ae4dc2a86cd99ea5e54c2d
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255344 (2021)
PurposeThe role of fibroblast growth factor (FGF) in orbital fibroblasts (OFs) is rarely known. In this study, we investigated the effect of FGF10 on fibrosis and the inflammation mechanism of Graves' orbitopathy (GO).MethodsOrbital tissue from GO (n
Externí odkaz:
https://doaj.org/article/3c5f58a89724410bb727d210159c00f1
Autor:
Sun Young Jang, Reza Saadati
Publikováno v:
Journal of Function Spaces, Vol 2020 (2020)
We solve the additive ϱ1,ϱ2-random operator inequality ξtTω,u+v−Tω,u−Tω,v≥κMξtϱ1Tω,u+v+Tω,u−v−2Tω,u,ξtϱ22Tω,u+v/2−Tω,u−Tω,v, in which ϱ1,ϱ2∈ℂ are fixed and max2ϱ1,ϱ2
Externí odkaz:
https://doaj.org/article/f78e94c5713b4500a3870924e23e0349
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background We developed a novel surgical technique to treat punctal stenosis involving the placement of three interrupted sutures after rectangular three-snip punctoplasty (TSP). Methods Retrospective chart review of forty-eight eyes of 44 p
Externí odkaz:
https://doaj.org/article/b2c1738ab8294ad0a67057bc60c86c02