Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sun W. Tam"'
Autor:
Joseph Kuo-Hsiang Tang, Farrokh Zare, Yadana Khin, Ying Xu, Sun W. Tam, Guillermo M. Muhlmann
Publikováno v:
Photosynthesis Research. 115:23-41
Chlorobaculum [Cba.] tepidum is known to grow optimally at 48-52 °C and can also be cultured at ambient temperatures. In this paper, we prepared constant temperature, temperature shift, and temperature shift followed by backshift cultures and invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9d905155e0ff27e1704cb7542aa384
https://doi.org/10.1007/s11120-013-9800-y
https://doi.org/10.1007/s11120-013-9800-y
Autor:
Dennis L. Guberski, Aldo A. Rossini, Dale L. Greiner, Annie J. Kruger, Rita Bortell, Douglas Hinerfeld, John P. Mordes, Karin M. Green, Chaoxing Yang, James E. Evans, Kejian Yang, John D. Leszyk, Sun W. Tam
Publikováno v:
Experimental Biology and Medicine. 235:1328-1337
Proteomic profiling of serum is a powerful technique to identify differentially expressed proteins that can serve as biomarkers predictive of disease onset. In this study, we utilized two-dimensional (2D) gel analysis followed by matrix-assisted-lase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09042bfb84dc71892a739b71641196d1
https://doi.org/10.1258/ebm.2010.010150
https://doi.org/10.1258/ebm.2010.010150
Autor:
Douglas Hinerfeld, Myrtle Davis, Sun W. Tam, Jennifer Rutherford-Bethard, Naijia H. Huang, Sajan Joseph, Yu-Hua Hui, John D. Leszyk
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:589-595
Therapeutic strategies focused on kinase inhibition rely heavily on surrogate measures of kinase inhibition obtained from in vitro assay systems. There is a need to develop methodology that will facilitate measurement of kinase inhibitor activity or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0d7d9693f54e1972b41d10e8c832a1
https://doi.org/10.1124/jpet.105.100032
https://doi.org/10.1124/jpet.105.100032
Publikováno v:
Expert Review of Proteomics. 1:411-420
This review intends to survey the traditional and current technologies in the depletion and subfractionation of plasma proteins for further analyses. The value of depletion aims to enrich low-abundant proteins by removing highly abundant proteins, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41a0338930e48fe5e43a279b202425b
https://doi.org/10.1586/14789450.1.4.411
https://doi.org/10.1586/14789450.1.4.411
Publikováno v:
Journal of Immunological Methods. 261:157-165
The adaptive immune system induces T cells to change from a naive phenotype to a Th1/Th2 phenotype each of which produce characteristic types of cytokines. Knowledge of whether a specific immune response is Th1 or Th2 is a useful indicator for diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf7640dc9662139bea3fd618033f869
https://doi.org/10.1016/s0022-1759(01)00572-5
https://doi.org/10.1016/s0022-1759(01)00572-5
Autor:
Sun W. Tam, Giulio Draetta, Michelangelo Fiorentino, Michele Pagano, Phillip T. Lavin, Massimo Loda, J. M. Jessup, Barry Cukor
Publikováno v:
Nature Medicine. 3:231-234
The cell-cycle inhibitor p27 is a potential tumor suppressor, but its gene has never been found inactivated in human tumors1–4. Because cell-cycle regulation of p27 cellular abundance occurs at the post-transcriptional level5–7, we analyzed p27 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47798de85465b1460f5bee5b5b74f99
https://doi.org/10.1038/nm0297-231
https://doi.org/10.1038/nm0297-231
Autor:
Vincent Chau, Peggy Beer-Romero, Anne M. Theodoras, Sun W. Tam, Giulio Draetta, Michele Pagano, Mark Rolfe, Giannino Del Sal, P. Renee Yew
Publikováno v:
Science. 269:682-685
The p27 mammalian cell cycle protein is an inhibitor of cyclin-dependent kinases. Both in vivo and in vitro, p27 was found to be degraded by the ubiquitin-proteasome pathway. The human ubiquitin-conjugating enzymes Ubc2 and Ubc3 were specifically inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b314e3927c9c406f91bf0c904dcb69
https://doi.org/10.1126/science.7624798
https://doi.org/10.1126/science.7624798
Publikováno v:
Genes & Development. 8:1627-1639
Cyclin D1 is a key regulator of the G1 phase of the cell cycle. Inhibition of cyclin D1 function results in cell cycle arrest, whereas unregulated expression of the protein accelerates G1. Cyclin D1 is localized to the nucleus during G1. We found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3322da1af07c27e9786f337137baf3cf
https://doi.org/10.1101/gad.8.14.1627
https://doi.org/10.1101/gad.8.14.1627
Publikováno v:
Proceedings of the National Academy of Sciences. 91:3754-3758
Apoptosis was induced in S-phase-arrested HeLa cells by staurosporine, caffeine, 6-dimethylaminopurine, and okadaic acid, agents that activate M-phase-promoting factor and induce premature mitosis in similarly treated hamster cell lines. Addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193af9ac8f75bd9b6ac62184936d1b33
https://doi.org/10.1073/pnas.91.9.3754
https://doi.org/10.1073/pnas.91.9.3754
Publikováno v:
Gene. 139:171-176
We have isolated two cathepsin B (CTSB)-encoding cDNAs, h CBF 1 and h CBF2 , from a normal human embryonic fibro blast library. These clones demonstrate 98% identity to overlapping regions of published human hepatoma and kidney CTSB cDNAs, but show s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8cc0d4052339750a8d37889a0f6861
https://doi.org/10.1016/0378-1119(94)90751-x
https://doi.org/10.1016/0378-1119(94)90751-x