Plant Extracts as a Source of Natural Products with Potential Antimalarial Effects: An Update from 2018 to 2022

Autor: Giovane de Jesus Gomes Ribeiro, Sun Liu Rei Yan, Giuseppe Palmisano, Carsten Wrenger

Publikováno v: Pharmaceutics, Vol 15, Iss 6, p 1638 (2023)

Malaria kills more than 500,000 people yearly, mainly affecting Africa and Southeast Asia. The disease is caused by the protozoan parasite from the genus Plasmodium, with Plasmodium vivax and Plasmodium falciparum being the main species that cause th

Externí odkaz: https://doaj.org/article/85b636b592e940ccb9baacb86344adcf

Lipoic Acid Metabolism as a Potential Chemotherapeutic Target Against Plasmodium falciparum and Staphylococcus aureus

Autor: Carsten Wrenger, Sun Liu Rei Yan, Felipe Wakasuqui, Matthew Groves, Xiaochen Du

Publikováno v: Frontiers in Chemistry, Vol 9 (2021)
Frontiers in Chemistry
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Lipoic acid (LA) is an organic compound that plays a key role in cellular metabolism. It participates in a posttranslational modification (PTM) named lipoylation, an event that is highly conserved and that occurs in multimeric metabolic enzymes of ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32842f3e8c30fa9e255bda5a2b9a4d76
https://www.frontiersin.org/articles/10.3389/fchem.2021.742175/full