Zobrazeno 1 - 10
of 4 532
pro vyhledávání: '"Sun Choi"'
Autor:
Shinwoo Kang, Jeyeon Lee, Dina N. Ali, Sun Choi, Jarred Nesbitt, Paul H. Min, Eugenia Trushina, Doo-Sup Choi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Alcohol use disorder has been associated with the development of neurodegenerative diseases, including Alzheimer’s disease (AD). However, recent studies demonstrate that moderate alcohol consumption may be protective against dementia and c
Externí odkaz:
https://doaj.org/article/4b6408f843ce404fba7d1d66cd3f7a9b
Autor:
Hyunji Kang, Ah-reum Han, Aihua Zhang, Heejin Jeong, Wuhyun Koh, Jung Moo Lee, Hayeon Lee, Hee Young Jo, Miguel A. Maria-Solano, Mridula Bhalla, Jea Kwon, Woo Suk Roh, Jimin Yang, Hyun Joo An, Sun Choi, Ho Min Kim, C. Justin Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Impaired ion channels regulating Golgi pH lead to structural alterations in the Golgi apparatus, such as fragmentation, which is found, along with cognitive impairment, in Alzheimer’s disease. However, the causal relationship between alter
Externí odkaz:
https://doaj.org/article/e0bbc7681bbb40cb81ceba4bc8f53496
Autor:
Ji Eon Kim, So‐Young Park, Chulhwan Kwak, Yoonji Lee, Dae‐Geun Song, Jae Woo Jung, Haesong Lee, Eun‐Ae Shin, Yangie Pinanga, Kyung‐hee Pyo, Eun Hae Lee, Wonsik Kim, Soyeon Kim, Chang‐Duck Jun, Jeanho Yun, Sun Choi, Hyun‐Woo Rhee, Kwang‐Hyeon Liu, Jung Weon Lee
Publikováno v:
Cancer Communications, Vol 44, Iss 1, Pp 47-75 (2024)
Abstract Background Transmembrane 4 L six family member 5 (TM4SF5) translocates subcellularly and functions metabolically, although it is unclear how intracellular TM4SF5 translocation is linked to metabolic contexts. It is thus of interests to under
Externí odkaz:
https://doaj.org/article/46fc9bb08a664adcac5b903aa7d00a58
Autor:
Xingshu Li, Jae Sang Oh, Yoonji Lee, Eun Chae Lee, Mengyao Yang, Nahyun Kwon, Tae Won Ha, Dong-Yong Hong, Yena Song, Hyun Kyu Kim, Byung Hoo Song, Sun Choi, Man Ryul Lee, Juyoung Yoon
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-14 (2023)
Abstract Background Malignant glioma is among the most lethal and frequently occurring brain tumors, and the average survival period is 15 months. Existing chemotherapy has low tolerance and low blood-brain barrier (BBB) permeability; therefore, the
Externí odkaz:
https://doaj.org/article/f6d475a1cc604be5a697405a2a455ee8
Autor:
Miguel A Maria-Solano, Sun Choi
Publikováno v:
eLife, Vol 12 (2023)
G-protein coupled receptors (GPCRs) present specific activation pathways and signaling among receptor subtypes. Hence, an extensive knowledge of the structural dynamics of the receptor is critical for the development of therapeutics. Here, we target
Externí odkaz:
https://doaj.org/article/f81c9cc2f0d34c25af93e770099bb800
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 286-310 (2022)
Ototoxicity is the drug-induced damage of the inner ear, causing bilateral irreversible sensorineural hearing loss. Cisplatin is a widely used chemotherapeutic agent which causes ototoxicity as its side effect. Pretreatment with metformin prior to th
Externí odkaz:
https://doaj.org/article/70644c5eee3a43018b8669288bf3f315
Publikováno v:
Medicina, Vol 59, Iss 10, p 1802 (2023)
Background: Organized hematoma in the sphenoid sinus is rare, but serious complications, such as visual deficits, can occur. Three such case reports have been published previously in the literature; however, none have achieved complete recovery of th
Externí odkaz:
https://doaj.org/article/c72f2bbf9465464d97c6524f6e062072
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alcohol use disorder (AUD) is characterized as a chronic, relapsing disease with a pattern of excessive drinking despite negative consequences to an individual’s life. Severe chronic alcohol use impairs the function of the medial prefrontal cortex
Externí odkaz:
https://doaj.org/article/414f555b714042c7b39dc272b9ebe44a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6032 (2021)
The new advances in deep learning methods have influenced many aspects of scientific research, including the study of the protein system. The prediction of proteins’ 3D structural components is now heavily dependent on machine learning techniques t
Externí odkaz:
https://doaj.org/article/564622559ea9454a9fed0cb427e8d3b5
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3241 (2021)
G protein-coupled receptor (GPCR) oligomerization, while contentious, continues to attract the attention of researchers. Numerous experimental investigations have validated the presence of GPCR dimers, and the relevance of dimerization in the effectu
Externí odkaz:
https://doaj.org/article/4da416db7b9a4b31958e4dc796d920ca