Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sun Ah Nam"'
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 886 (2024)
Autophagy is a cellular process that degrades damaged cytoplasmic components and regulates cell death. The homeostasis of endothelial cells (ECs) is crucial for the preservation of glomerular structure and function in aging. Here, we investigated the
Externí odkaz:
https://doaj.org/article/380b1eb2f7ca4293a014ebb978ddfe40
Autor:
Keonhyeok Park, Jong Young Lee, Soo Young Lee, Iljoo Jeong, Seo-Yeon Park, Jin Won Kim, Sun Ah Nam, Hyung Wook Kim, Yong Kyun Kim, Seungchul Lee
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 1, Pp 75-85 (2023)
Background Kidney organoids derived from human pluripotent stem cells (hPSCs) contain multilineage nephrogenic progenitor cells and can recapitulate the development of the kidney. Kidney organoids derived from hPSCs have the potential to be applied i
Externí odkaz:
https://doaj.org/article/e7719f4b5c374fcc8af57ff7076b3275
Autor:
Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun Kim
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 6, Pp 1420-1436 (2021)
Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized exper
Externí odkaz:
https://doaj.org/article/1cdcf2c8f8544d2a884a0e270371f0bb
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Organoids that mimic the structural and cellular characteristics of kidneys in vitro have recently emerged as a promising source for biomedical research. However, uncontrollable cellular heterogeneity after differentiation often results in t
Externí odkaz:
https://doaj.org/article/4b89bdb141e04be59e97d4651df586c9
Autor:
Jin Won Kim, Sun Ah Nam, Jawoon Yi, Jae Yun Kim, Jong Young Lee, Seo‐Yeon Park, Tugce Sen, Yoo‐mi Choi, Jae Yeon Lee, Hong Lim Kim, Hyung Wook Kim, Jiwhan Park, Dong‐Woo Cho, Yong Kyun Kim
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Kidney organoids derived from human pluripotent stem cells (hPSCs) have extensive potential for disease modelling and regenerative medicine. However, the limited vascularization and immaturity of kidney organoids have been still remained to
Externí odkaz:
https://doaj.org/article/373f81733f7445ebb9d81ff268d0ae7f
Autor:
Yu-Mi Kim, Wan-Young Kim, Sun Ah Nam, A-Rum Choi, Hyang Kim, Yong-Kyun Kim, Hak-Soo Kim, Jin Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127429 (2015)
The homeobox transcription factor Prox1 is critical to the development of many embryonic organs and tissues, although current understanding of its expression in the developing renal medulla is limited. We examined the functional role of Prox1 during
Externí odkaz:
https://doaj.org/article/6faae402849946f5955060df0c261d0f
Autor:
Yu-Mi Kim, Wan-Young Kim, Sun Ah Nam, A-Rum Choi, Hyang Kim, Yong-Kyun Kim, Hak-Soo Kim, Jin Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139498 (2015)
Externí odkaz:
https://doaj.org/article/a84f52192c4749c584963f303776209e
Autor:
Tae Min Kim, Hyung Wook Kim, Hae Jin Cho, Jong Young Lee, Sun Ah Nam, Jin Won Kim, Yong Kyun Kim
Publikováno v:
Experimental & Molecular Medicine
Fabry disease is an X-linked lysosomal storage disease caused by a mutation in the galactosidase alpha (GLA) gene. Despite advances in therapeutic technologies, the lack of humanized experimental models of Fabry disease has limited the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71389375bd16b91dc448756977c3e612
http://europepmc.org/articles/PMC8568890
http://europepmc.org/articles/PMC8568890
Autor:
Jong Hoon Park, Sumin Oh, Kyung Hyun Yoo, Yong Kyun Kim, Minah Park, Eunjeong Seo, Jin Won Kim, Eun Ji Lee, Eek-hoon Jho, Jong Young Lee, Sun Ah Nam, Jaehee Jun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Autosomal-dominant polycystic kidney disease (ADPKD) is the most common genetic renal disease, primarily caused by germline mutation of PKD1 or PKD2, leading to end-stage renal disease. There are few cures for ADPKD, although many resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02aed9f672ab7230ee18e53a8137299f
https://doi.org/10.1073/pnas.2009334117
https://doi.org/10.1073/pnas.2009334117
Publikováno v:
The Korean Journal of Internal Medicine
The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479d7386e1530ce2b307656cd0e9a0cc
https://doi.org/10.3904/kjim.2018.198
https://doi.org/10.3904/kjim.2018.198