Kinetic Modeling of the Antibody Disulfide Bond Reduction Reaction With Integrated Prediction of the Drug Load Profile for Cysteine-Conjugated ADCs.

Autor: Weggen JT; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Baden-Württemberg, Germany., González P; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Baden-Württemberg, Germany., Hui K; Purification Process Sciences, Biopharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Bean R; Purification Process Sciences, Biopharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Wendeler M; Purification Process Sciences, Biopharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Hubbuch J; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Baden-Württemberg, Germany.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2024 Dec 17. Date of Electronic Publication: 2024 Dec 17.

Evaluation of hydrophobic‐interaction chromatography resins for purification of antibody‐drug conjugates using a mimetic model with adjustable hydrophobicity.

Autor: Müller, Egbert¹ (AUTHOR) egbert.mueller@tosoh.com, Sevilla, Manuela¹ (AUTHOR), Endres, Patrick¹ (AUTHOR)

Publikováno v: Journal of Separation Science. Jun2020, Vol. 43 Issue 12, p2255-2263. 9p.

Coordinatively Unsaturated Metal–Nitrogen Active Sites at Twisted Surfaces in Metallic Porous Nitride Single Crystals Delivering Enhanced Electrocatalysis Activity.

Autor: Zhang, Feiyan¹ (AUTHOR), Jin, Lu¹ (AUTHOR), Li, Hao¹ (AUTHOR), Xie, Kui¹ (AUTHOR) kxie@fjirsm.ac.cn

Publikováno v: Chemistry - A European Journal. 2/21/2020, Vol. 26 Issue 11, p2327-2332. 6p.

Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy.

Autor: de Faria e Silva, Ana L., Ryder, Alan G.

Publikováno v: Biotechnology & Bioengineering; Dec2022, Vol. 119 Issue 12, p3432-3446, 15p

Use of group 13 aryloxides for the synthesis of green chemicals and oxide materials.

Autor: Petrus, Rafał, Utko, Józef, Petrus, Joanna, Awashra, Mohammad, Lis, Tadeusz

Publikováno v: Dalton Transactions: An International Journal of Inorganic Chemistry; 3/14/2022, Vol. 51 Issue 10, p4135-4152, 18p