Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sumudu V. S. Gangoda"'
1
Multi-tissue lipotoxicity caused by high-fat diet feeding is attenuated by the supplementation of Korean red ginseng in mice
Autor: Ki-Hyo Jang, Seon-A Jang, Hyun Jung Koo, Seung Namkoong, Eun-Hwa Sohn, Alberto Avolio, Se Chan Kang, Sung Ryul Lee, Sumudu V. S. Gangoda, Myung Kyum Kim, Sung Hyeok Kim, Gyeongseop So, Yuna Park, Mi-Ja Kim, Jin Woo Lee
Publikováno v: Molecular & Cellular Toxicology. 16:39-50
Excessive intake of fat, one of the causes of obesity, is associated with low-grade inflammation in various susceptible organs and eventually causes tissue toxicity. This study examines the multifaceted suppressive effects of Korean red ginseng extra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::431db195ed3dc42d41b6a2cb73e82147
https://doi.org/10.1007/s13273-019-00056-7
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2
Pulsatile stretch as a novel modulator of amyloid precursor protein processing and associated inflammatory markers in human cerebral endothelial cells
Autor: Nurul Farhana Jufri, Sumudu V. S. Gangoda, Roger S. Chung, Bhargava Avadhanam, Eun Hwa Sohn, Alberto Avolio, Mark Butlin, Vivek Gupta
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Amyloid β (Aβ) deposition is a hallmark of Alzheimer’s disease (AD). Vascular modifications, including altered brain endothelial cell function and structural viability of the blood-brain barrier due to vascular pulsatility, are implicated in AD p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b794a302b0a790b767692d4e6d3d18f4
http://link.springer.com/article/10.1038/s41598-018-20117-6
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3
Postural effects on spontaneous retinal venous pulsations in healthy individuals
Autor: Dana Georgevsky, Seyyed Mojtaba Golzan, Sumudu V. S. Gangoda
Publikováno v: Acta Ophthalmologica. 97
PURPOSE To assess amplitudes of spontaneous retinal venous pulsations (SVP) in three various postures (sitting, supine and lateral decubitus) in healthy individuals. METHODS Thirty participants (28 ± 8 years, 25 females) were included in the study.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab583f2e25292983968ee76922fbcaa4
https://doi.org/10.1111/aos.14068
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4
One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina
Autor: Yogita Dheer, Tejal M. Shah, Roshana Vander Wall, Stuart L. Graham, Vivek Gupta, Ralph N. Martins, Mojtaba Golzan, Mojdeh Abbasi, Sumudu V. S. Gangoda, Alberto Avolio, Nitin Chitranshi, Veer Bala Gupta, Roger S. Chung
Publikováno v: Cellular and Molecular Life Sciences. 73:4279-4297
Accumulation of amyloid β (Aβ) and its aggregates in the ageing central nervous system is regarded synonymous to Alzheimer's disease (AD) pathology. Despite unquestionable advances in mechanistic and diagnostic aspects of the disease understanding,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206229e4fd911f7ef5e38711e5c1e3bf
https://doi.org/10.1007/s00018-016-2295-x
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5
Cerebral Haemodynamics: Effects of Systemic Arterial Pulsatile Function and Hypertension
Autor: Sumudu V. S. Gangoda, Audrey Adji, Alberto Avolio, Bhargava Avadhanam, Isabella Tan, Mi Ok Kim, Mark Butlin
Publikováno v: Current hypertension reports. 20(3)
Concepts of pulsatile arterial haemodynamics, including relationships between oscillatory blood pressure and flow in systemic arteries, arterial stiffness and wave propagation phenomena have provided basic understanding of underlying haemodynamic mec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0bbbf99539cc90fd5c4fb521122883
https://pubmed.ncbi.nlm.nih.gov/29556793
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9
[OP.2D.03] PULSATILE STRETCH ALTERS EXPRESSION AND PROCESSING OF AMYLOID PRECURSOR PROTEIN IN HUMAN CEREBRAL ENDOTHELIAL CELLS
Autor: Vivek Gupta, Roger S. Chung, Sumudu V. S. Gangoda, Alberto Avolio, Mark Butlin
Publikováno v: Journal of Hypertension. 34:e24
Amyloid β (Aβ) deposition is a hallmark of Alzheimer's disease (AD). Aβ is generated via enzymatic cleavage of amyloid precursor protein (APP). Increased APP expression is associated with elevated amyloid burden. Elevated pulsatility of arterial p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b186d66434ac492718387e8b9042db7
https://doi.org/10.1097/01.hjh.0000491393.79855.fc
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