Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Summer Siddiqui"'
Autor:
Xiaolei Wang, Eunice Vincent, Summer Siddiqui, Katherine Turnbull, Hong Lu, Robert Blair, Xueling Wu, Meagan Watkins, Widade Ziani, Jiasheng Shao, Lara A. Doyle-Meyers, Kasi E. Russell-Lodrigue, Rudolf P. Bohm, Ronald S. Veazey, Huanbin Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Neonates and infants infected with HIV generally develop disease rapidly, with early antiretroviral therapy (ART) often failing to achieve a sustained state of ART-free virologic remission. Here, the authors study viral reservoirs in neonatal macaque
Externí odkaz:
https://doaj.org/article/a089ce684ba34eaea4f2392b41d03fe2
Autor:
Pietro Mancuso, Chen Chen, Rafal Kaminski, Jennifer Gordon, Shuren Liao, Jake A. Robinson, Mandy D. Smith, Hong Liu, Ilker K. Sariyer, Rahsan Sariyer, Tiffany A. Peterson, Martina Donadoni, Jaclyn B. Williams, Summer Siddiqui, Bruce A. Bunnell, Binhua Ling, Andrew G. MacLean, Tricia H. Burdo, Kamel Khalili
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Removal of integrated HIV DNA remains a roadblock for HIV cure. Here, Mancuso et al. show that intravenous administration of an adeno-associated virus-based CRISPR/Cas9 gene editing construct to SIV-infected macaques results in excision of integrated
Externí odkaz:
https://doaj.org/article/8cbe71bbcb2e47d19d5219446802dbe4
Neuroinflammatory Profiling in SIV-Infected Chinese-Origin Rhesus Macaques on Antiretroviral Therapy
Autor:
Antonio Solis-Leal, Summer Siddiqui, Fei Wu, Mahesh Mohan, Wenhui Hu, Lara A. Doyle-Meyers, Jason P. Dufour, Binhua Ling
Publikováno v:
Viruses, Vol 14, Iss 1, p 139 (2022)
The central nervous system (CNS) HIV reservoir is an obstacle to achieving an HIV cure. The basal ganglia harbor a higher frequency of SIV than other brain regions in the SIV-infected rhesus macaques of Chinese-origin (chRMs) even on suppressive comb
Externí odkaz:
https://doaj.org/article/176c6391be914032b081df1824e3bcdd
Autor:
Summer Siddiqui, Stefanie Perez, Yong Gao, Lara Doyle-Meyers, Brian T Foley, Qingsheng Li, Binhua Ling
Publikováno v:
Viruses, Vol 11, Iss 2, p 105 (2019)
Understanding HIV latent reservoirs in tissues is essential for the development of new strategies targeting these sites for eradication. Here, we assessed the size of latent reservoirs and the source of residual viruses in multiple lymphoid tissues o
Externí odkaz:
https://doaj.org/article/5ff305e0874640bca7ac9686ab0c8807
Autor:
Hong Lu, Lara A. Doyle-Meyers, Rudolf P. Bohm, Summer Siddiqui, Widade Ziani, Robert V Blair, Xiaolei Wang, Jiasheng Shao, Kasi E. Russell-Lodrigue, Huanbin Xu, Ronald S. Veazey, Eunice Vincent, Xueling Wu
Neonatal HIV infection causes rapid disease progression to end-stage of AIDS if untreated. To date, there are no reported cases of a genuine functional cure in Pediatric AIDS ClinicalTrial Group lacking integrase inhibitor regimen, even when initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84396f5aa5f4adb798a3e76ed98a06a9
https://doi.org/10.21203/rs.3.rs-426657/v1
https://doi.org/10.21203/rs.3.rs-426657/v1
Autor:
Kamel Khalili, Mandy D. Smith, Rahsan Sariyer, Pietro Mancuso, Jennifer Gordon, Bruce A. Bunnell, Hong Liu, Rafal Kaminski, Tricia H. Burdo, Ilker Kudret Sariyer, Jake A. Robinson, Tiffany A. Peterson, Andrew G. MacLean, Martina Donadoni, Binhua Ling, Summer Siddiqui, Shuren Liao, Chen Chen, Jaclyn B. Williams
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Elimination of HIV DNA from infected individuals remains a challenge in medicine. Here, we demonstrate that intravenous inoculation of SIV-infected macaques, a well-accepted non-human primate model of HIV infection, with adeno-associated virus 9 (AAV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff0bd71330bda63430b939d74e604d9
https://doi.org/10.1038/s41467-020-19821-7
https://doi.org/10.1038/s41467-020-19821-7
Autor:
Jason Dufour, Yao-Zhong Liu, Summer Siddiqui, Binhua Ling, Yuntao Wu, Duran Bao, Lara A. Doyle-Meyers
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Gut dysbiosis and microbial translocation are associated with chronic systemic immune activation and inflammation in HIV-1 infection. However, the extent of restoration of gut microbiota in HIV-1 patients with short or long-term antiretroviral therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02022ecae88e3defacc4aed6c348edf
https://pubmed.ncbi.nlm.nih.gov/33149234
https://pubmed.ncbi.nlm.nih.gov/33149234
Autor:
Qingsheng Li, Yong Gao, Brian T. Foley, Lara A. Doyle-Meyers, Binhua Ling, Summer Siddiqui, Stefanie Perez
Publikováno v:
Viruses
Viruses, Vol 11, Iss 2, p 105 (2019)
Volume 11
Issue 2
Viruses, Vol 11, Iss 2, p 105 (2019)
Volume 11
Issue 2
Understanding HIV latent reservoirs in tissues is essential for the development of new strategies targeting these sites for eradication. Here, we assessed the size of latent reservoirs and the source of residual viruses in multiple lymphoid tissues o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ee36e02907aa49f442c694b2db3863
https://doi.org/10.3390/v11020105
https://doi.org/10.3390/v11020105