Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Summer E, Galloway"'
Autor:
Anastasia S, Lambrou, Philip, Shirk, Molly K, Steele, Prabasaj, Paul, Clinton R, Paden, Betsy, Cadwell, Heather E, Reese, Yutaka, Aoki, Norman, Hassell, Xiao-Yu, Zheng, Sarah, Talarico, Jessica C, Chen, M Steven, Oberste, Dhwani, Batra, Laura K, McMullan, Alison Laufer, Halpin, Summer E, Galloway, Duncan R, MacCannell, Rebecca, Kondor, John, Barnes, Adam, MacNeil, Benjamin J, Silk, Vivien G, Dugan, Heather M, Scobie, David E, Wentworth, Jason, Caravas, Nicholas A, Kovacs, Jonathan G, Gerhart, Han, Jia Ng, Andrew, Beck, Reina, Chau, Roxana, Cintron, Peter W, Cook, Christopher A, Gulvik, Dakota, Howard, Yunho, Jang, Kristen, Knipe, Kristine A, Lacek, Kara A, Moser, Adrian C, Paskey, Benjamin L, Rambo-Martin, Roopa R, Nagilla, Adam C, Retchless, Matthew W, Schmerer, Sandra, Seby, Samuel S, Shepard, Richard A, Stanton, Thomas J, Stark, Anna, Uehara, Yvette, Unoarumhi, Meghan L, Bentz, Alex, Burgin, Mark, Burroughs, Morgan L, Davis, Matthew W, Keller, Lisa M, Keong, Shoshona S, Le, Justin S, Lee, Joseph C, Madden Jr, Sarah, Nobles, D. Collins, Owuor, Jasmine, Padilla, Mili, Sheth, Malania M, Wilson
Publikováno v:
MMWR. Morbidity and mortality weekly report. 71(6)
Genomic surveillance is a critical tool for tracking emerging variants of SARS-CoV-2 (the virus that causes COVID-19), which can exhibit characteristics that potentially affect public health and clinical interventions, including increased transmissib
Autor:
Benjamin J. Silk, Adam MacNeil, Rachel B. Slayton, Gregory L. Armstrong, Prabasaj Paul, John T. Brooks, Vivien G. Dugan, Michael A. Johansson, Suxiang Tong, Duncan MacCannell, Matthew Biggerstaff, Summer E. Galloway
Publikováno v:
Morbidity and Mortality Weekly Report
On December 14, 2020, the United Kingdom reported a SARS-CoV-2 variant of concern (VOC), lineage B.1.1.7, also referred to as VOC 202012/01 or 20I/501Y.V1.* The B.1.1.7 variant is estimated to have emerged in September 2020 and has quickly become the
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003151 (2013)
The influenza A virus (IAV) HA protein must be activated by host cells proteases in order to prime the molecule for fusion. Consequently, the availability of activating proteases and the susceptibility of HA to protease activity represents key factor
Externí odkaz:
https://doaj.org/article/e4ca1d24a55049dd8d60ea9a20c11305
Autor:
Bo Liang, Jessica F. Trost, Wei Wang, Lauren Byrd-Leotis, David A. Steinhauer, Evangeline Agbogu, Summer E. Galloway
Publikováno v:
Virology
Influenza A viruses enter host cells through the endocytic pathway, where acidification triggers conformational changes of the viral hemagglutinin (HA) to drive membrane fusion. During this process, the HA fusion peptide is extruded from its buried p
Autor:
Xi Chen, Jamie Heimburg-Molinaro, Xuezheng Song, Yi Lasanajak, David F. Smith, Hai Yu, Ganesh R. Talekar, Richard D. Cummings, David A. Steinhauer, Konrad C. Bradley, Summer E. Galloway
Publikováno v:
Journal of Virology. 85:12387-12398
To examine the range of selective processes that potentially operate when poorly binding influenza viruses adapt to replicate more efficiently in alternative environments, we passaged a virus containing an attenuating mutation in the hemagglutinin (H
Autor:
Konrad C. Bradley, Zhu-Nan Li, William A. Langley, Ganesh R. Talekar, Summer E. Galloway, David A. Steinhauer
Publikováno v:
Vaccine. 28:6305-6313
The use of viral vectors as vaccine candidates has shown promise against a number of pathogens. However, preexisting immunity to these vectors is a concern that must be addressed when deciding which viruses are suitable for use. A number of propertie
Autor:
William A. Langley, E. Varečková, Ru Pert J. Russell, Konrad C. Bradley, Summer E. Galloway, Sudha Thoennes, Sandra F. Cummings, David A. Steinhauer, Ganesh R. Talekar
Publikováno v:
Virology. 394:321-330
A panel of eight single amino acid deletion mutants was generated within the first 24 residues of the fusion peptide domain of the of the hemagglutinin (HA) of A/Aichi/2/68 influenza A virus (H3N2 subtype). The mutant HAs were analyzed for folding, c
Publikováno v:
Virology. 382(1):69-82
The large (L) proteins of non-segmented negative stranded (NNS) RNA viruses contain the core RNA dependent RNA polymerase activity for RNA replication and transcription as well as the activities for polyadenylating and capping the mRNA transcripts an
Influenza A viruses enter host cells through endosomes, where acidification induces irreversible conformational changes of the viral hemagglutinin (HA) that drive the membrane fusion process. The prefusion conformation of the HA is metastable, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6e505ba931a385fe1e4aa944ea847a
https://europepmc.org/articles/PMC4442347/
https://europepmc.org/articles/PMC4442347/
Autor:
Marie R. Culhane, Sandra F. Cummings, Lauren Byrd-Leotis, Summer E. Galloway, David A. Steinhauer, Jamie Heimburg-Molinaro, Konrad C. Bradley, Yi Lasanajak, Renpeng Liu, Richard D. Cummings, David F. Smith, Xuezheng Song
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(22)
Influenza viruses bind to host cell surface glycans containing terminal sialic acids, but as studies on influenza binding become more sophisticated, it is becoming evident that although sialic acid may be necessary, it is not sufficient for productiv