Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sumitra Tavornvipas"'
6-O-α-(4-O-α-d-glucuronyl)-d-glucosyl-β-cyclodextrin: solubilizing ability and some cellular effects
Autor:
Kaneto Uekama, Hidetoshi Arima, Hitoshi Hashimoto, Fumitoshi Hirayama, Toshihiro Ishiguro, Kenichi Hamayasu, Masahide Oka, Sumitra Tavornvipas
Publikováno v:
International Journal of Pharmaceutics. 249:199-209
Some physicochemical and biopharmaceutical properties of a new branched cyclodextrin, 6-O-alpha-(4-O-alpha-D-glucuronyl)-D-glucosyl-beta-cyclodextrin (GUG-beta-CyD), were investigated. The interaction of GUG-beta-CyD with drugs was studied by spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a116f2ea77f633cd7af18f0c6292b7d3
https://doi.org/10.1016/s0378-5173(02)00537-9
https://doi.org/10.1016/s0378-5173(02)00537-9
Autor:
Hidetoshi Arima, Hitoshi Hashimoto, Kaneto Uekama, Fumitoshi Hirayama, Toshihiro Ishiguro, Kenichi Hamayasu, Masahide Oka, Sumitra Tavornvipas
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 44:391-394
Some physicochemical and biological properties of a new branched cyclodextrin, 6-O-α-(4-O-α-d-glucuronyl)-d-glucosyl-β-cyclodextrin GUG-β-CyD) were investigated. Further, theinteraction of GUG-β-CyD with several drugs was studied by the solubili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::706b4e2fae5bb47169257dcd096ba8ae
https://doi.org/10.1023/a:1023067232328
https://doi.org/10.1023/a:1023067232328
Autor:
Arimichi Okazaki, Sumitra Tavornvipas, Kiyohiko Sugano, Atsushi Omura, Takashi Mano, Shohei Sugimoto
Publikováno v:
Drug metabolism and pharmacokinetics. 22(4)
The purposes of the review are to: a) Provide a comprehensible introduction of the-state-of-the-art sciences of solubility and dissolution, b) introduce typical technologies to assess solubility and dissolution, and c) propose the best practice strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0252982fa7d607fa83d0fa24892071dc
https://pubmed.ncbi.nlm.nih.gov/17827779
https://pubmed.ncbi.nlm.nih.gov/17827779
Publikováno v:
Pharmaceutical research. 21(12)
To evaluate the effect of hydrophilic cyclodextrins (CyDs) on the aggregation induced by different stresses and on the oxidation and deamidation of recombinant human growth hormone (rhGH).The aggregation of rhGH was induced by three denaturing techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2c1c30146e8f2102cda6c28f52a37f
https://pubmed.ncbi.nlm.nih.gov/15648271
https://pubmed.ncbi.nlm.nih.gov/15648271
Autor:
Sumitra, Tavornvipas, Fumitoshi, Hirayama, Hidetoshi, Arima, Kaneto, Uekama, Toshihiro, Ishiguro, Masahide, Oka, Kenichi, Hamayasu, Hitoshi, Hashimoto
Publikováno v:
International journal of pharmaceutics. 249(1-2)
Some physicochemical and biopharmaceutical properties of a new branched cyclodextrin, 6-O-alpha-(4-O-alpha-D-glucuronyl)-D-glucosyl-beta-cyclodextrin (GUG-beta-CyD), were investigated. The interaction of GUG-beta-CyD with drugs was studied by spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea9d3436cafe4c6752db9974ed7ab2a2
https://pubmed.ncbi.nlm.nih.gov/12433448
https://pubmed.ncbi.nlm.nih.gov/12433448
Publikováno v:
Journal of Inclusion Phenomena & Macrocyclic Chemistry; Dec2002, Vol. 44 Issue 1-4, p391-394, 4p
Autor:
Kiyohiko Sugano
A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, in
