Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sumito Sunagawa"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Definitive differences in blood metabolite profiles between obese and non-obese Type 2 diabetes (T2D) have not been established. We performed an LC–MS-based non-targeted metabolomic analysis of whole blood samples collected from subjects c
Externí odkaz:
https://doaj.org/article/1cf27595930f4be896008f015cc85f16
Autor:
Sumito Sunagawa, Takashi Shirakura, Noboru Hokama, Chisayo Kozuka, Masato Yonamine, Toyotaka Namba, Satoko Morishima, Sawako Nakachi, Yukiko Nishi, Tomomi Ikema, Shiki Okamoto, Chieko Matsui, Naoki Hase, Mizuho Tamura, Michio Shimabukuro, Hiroaki Masuzaki
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 1, Pp 94-103 (2019)
Abstract Aims/Introduction There is controversy as to whether hyperuricemia is an independent risk factor for cardiometabolic diseases. The serum level of uric acid is affected by a wide variety of factors involved in its production and excretion. In
Externí odkaz:
https://doaj.org/article/cd6a659341364786b4783350e7923b31
Autor:
Sawako Nakachi, Katsunori Nakamura, Mizuho Tamura, Sumito Sunagawa, Hiroaki Masuzaki, Satoko Morishima, Shiki Okamoto, Noboru Hokama, Takashi Shirakura, Naoki Hase, Yukiko Nishi, Yuko Murayama, Chieko Matsui, Michio Shimabukuro
Publikováno v:
Hematological Oncology. 37:527-530
Autor:
Mizuho Tamura, Shiki Okamoto, Toyotaka Namba, Chisayo Kozuka, Hiroaki Masuzaki, Chieko Matsui, Masato Yonamine, Michio Shimabukuro, Sawako Nakachi, Sumito Sunagawa, Yukiko Nishi, Tomomi Ikema, Satoko Morishima, Noboru Hokama, Takashi Shirakura, Naoki Hase
Publikováno v:
Journal of Diabetes Investigation
Journal of Diabetes Investigation, Vol 10, Iss 1, Pp 94-103 (2019)
Journal of Diabetes Investigation, Vol 10, Iss 1, Pp 94-103 (2019)
Aims/Introduction There is controversy as to whether hyperuricemia is an independent risk factor for cardiometabolic diseases. The serum level of uric acid is affected by a wide variety of factors involved in its production and excretion. In contrast
Autor:
Michio Shimabukuro, Noboru Hokama, Sawako Nakachi, Takashi Shirakura, Satoko Morishima, Naoki Hase, Mizuho Tamura, Hiroaki Masuzaki, Shiki Okamoto, Yukiko Nishi, Yuko Murayama, Chieko Matsui, Katsunori Nakamura, Sumito Sunagawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44e12e379ba5fed1ffe95842efa5fdd
https://doi.org/10.1002/hon.2659/v2/response1
https://doi.org/10.1002/hon.2659/v2/response1
Autor:
Hiroaki Masuzaki, Moritake Higa, Hideaki Tanaka, Chisayo Kozuka, Masato Tsutsui, Yuzuru Ohshiro, Toshihiko Yada, Chigusa Shimizu-Okabe, Shogo Ishiuchi, Jun-ichi Miyazaki, Masanori Nakata, Rei Ueda, Chitoshi Takayama, Seiichi Oyadomari, Michio Shimabukuro, Sumito Sunagawa, Masayuki Matsushita
Publikováno v:
British Journal of Pharmacology. 172:4519-4534
Background and Purpose γ-Oryzanol, derived from unrefined rice, attenuated the preference for dietary fat in mice, by decreasing hypothalamic endoplasmic reticulum stress. However, no peripheral mechanisms, whereby γ-oryzanol could ameliorate gluco
Autor:
Chitoshi Takayama, Hiroaki Masuzaki, Shogo Ishiuchi, Seiichi Oyadomari, Michio Shimabukuro, Rei Ueda, Sumito Sunagawa, Moritake Higa, Chisayo Kozuka, Masato Tsutsui, Jun-ichi Miyazaki, Chigusa Shimizu-Okabe, Masayuki Matsushita, Hideaki Tanaka
Publikováno v:
Endocrinology. 156:1242-1250
Endoplasmic reticulum (ER) stress is profoundly involved in dysfunction of β-cells under high-fat diet and hyperglycemia. Our recent study in mice showed that γ-oryzanol, a unique component of brown rice, acts as a chemical chaperone in the hypotha
Autor:
Shin-ichiro Taira, Takako Iha, Sawako Nakachi, Michio Shimabukuro, Hiroaki Masuzaki, Kouichi Yabiku, Mototsugu Doi, Yoshiro Nakayama, Sumito Sunagawa, Toyotaka Nanba, Yuzuru Ohshiro, Tomomi Ikema, Hideaki Nakamura, Moritake Higa, Ken Yamakawa, Rei Ueda, Chisayo Kozuka, Takeaki Tomoyose, Eriko Kawamoto
Publikováno v:
Internal Medicine. 52:1561-1571
Objective In addition to excess visceral fat, lipid deposition in the liver and skeletal muscle has been implicated in the pathophysiology of type 2 diabetes and metabolic syndrome. This study was designed to explore the relationship between hepatic
Autor:
Chitoshi Takayama, Rei Ueda, Hideaki Tanaka, Chisayo Kozuka, Seiichi Oyadomari, Sumito Sunagawa, Masayuki Matsushita, Hiroaki Masuzaki, Kouichi Yabiku, Tomomi Ikema, Ken Yamakawa, Moritake Higa, Hiroyuki Ohshiro, Michio Shimabukuro, Shin-ichiro Taira
Publikováno v:
Diabetes
Brown rice is known to improve glucose intolerance and prevent the onset of diabetes. However, the underlying mechanisms remain obscure. In the current study, we investigated the effect of brown rice and its major component, γ-oryzanol (Orz), on fee
Autor:
Chisayo, Kozuka, Sumito, Sunagawa, Rei, Ueda, Moritake, Higa, Yuzuru, Ohshiro, Hideaki, Tanaka, Chigusa, Shimizu-Okabe, Chitoshi, Takayama, Masayuki, Matsushita, Masato, Tsutsui, Shogo, Ishiuchi, Masanori, Nakata, Toshihiko, Yada, Jun-Ichi, Miyazaki, Seiichi, Oyadomari, Michio, Shimabukuro, Hiroaki, Masuzaki
Publikováno v:
British journal of pharmacology. 172(18)
γ-Oryzanol, derived from unrefined rice, attenuated the preference for dietary fat in mice, by decreasing hypothalamic endoplasmic reticulum stress. However, no peripheral mechanisms, whereby γ-oryzanol could ameliorate glucose dyshomeostasis were