Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sumit Rawal"'
Autor:
Melissa S Monson, Robert E Settlage, Kevin W McMahon, Kristelle M Mendoza, Sumit Rawal, Hani S El-Nezami, Roger A Coulombe, Kent M Reed
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100930 (2014)
Dietary exposure to aflatoxin B1 (AFB1) is detrimental to avian health and leads to major economic losses for the poultry industry. AFB1 is especially hepatotoxic in domestic turkeys (Meleagris gallopavo), since these birds are unable to detoxify AFB
Externí odkaz:
https://doaj.org/article/e4fd88a31a2a43e8a6133ce33a0bc75e
Autor:
Carey K Anders, Barbara Adamo, Olga Karginova, Allison M Deal, Sumit Rawal, David Darr, Allison Schorzman, Charlene Santos, Ryan Bash, Tal Kafri, Lisa Carey, C Ryan Miller, Charles M Perou, Norman Sharpless, William C Zamboni
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61359 (2013)
Breast cancer brain metastases (BCBM) are a challenging consequence of advanced BC. Nanoparticle agents, including liposomes, have shown enhanced delivery to solid tumors and brain. We compared pharmacokinetics (PK) and efficacy of PEGylated liposoma
Externí odkaz:
https://doaj.org/article/2bf71838311046939dc207cf08041798
Autor:
Sumit Rawal, Anh Duong, Ishani Landry, Jagadeesh Aluri, Peter Boyd, Takuya Yagi, Chad J Swanson, Larisa Reyderman
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e4956bf9662a58dbb0e181453d6d0a
https://doi.org/10.1002/alz.069438
https://doi.org/10.1002/alz.069438
Publikováno v:
Sleep. 45:A201-A201
Introduction Some hypnotic treatments for insomnia require dosing consideration due to exposure differences based on patient characteristics. Lemborexant (LEM) is a dual orexin receptor antagonist approved in multiple countries for the treatment of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e5cb34534eb41c7e76df7d438d66c8
https://doi.org/10.1093/sleep/zsac079.450
https://doi.org/10.1093/sleep/zsac079.450
Autor:
Hani El-Nezami, Melissa S. Monson, Kent M. Reed, Kristelle M. Mendoza, Roger A. Coulombe, Sumit Rawal, Robert E. Settlage
Publikováno v:
Immunogenetics. 67:163-178
Poultry are highly susceptible to the immunotoxic effects of the food-borne mycotoxin aflatoxin B1 (AFB1). Exposure impairs cell-mediated and humoral immunity, limits vaccine efficacy, and increases the incidence of costly secondary infections. We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5f2ca354b7337f9c5ac101c4ef0b36
https://doi.org/10.1007/s00251-014-0825-y
https://doi.org/10.1007/s00251-014-0825-y
Autor:
Jeffery R. Hall, Ji Eun Kim, Kent M. Reed, Kristelle M. Mendoza, Miranda M. Bauer, Sumit Rawal, Roger A. Coulombe, Hani El-Nezami, John R. Stevens
Publikováno v:
Research in Veterinary Science. 97:274-281
Turkeys are extremely sensitive to aflatoxin B1 (AFB1) which causes decreased growth, immunosuppression and liver necrosis. The purpose of this study was to determine whether probiotic Lactobacillus, shown to be protective in animal and clinical stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3392d898c3758d5aca53a216977a090d
https://doi.org/10.1016/j.rvsc.2014.06.008
https://doi.org/10.1016/j.rvsc.2014.06.008
Publikováno v:
Cytogenetic and Genome Research. 125:67-73
Cytochromes P450 (P450 for protein; CYP for gene) are a superfamily of membrane-bound hemoproteins that oxidize a large number of endogenous and exogenous compounds. Through oxidation reactions, these enzymes are often responsible for the toxic and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13924913aebb39ab3b07baf9fbd84946
https://doi.org/10.1159/000218748
https://doi.org/10.1159/000218748
Autor:
Bernd Meibohm, Josiah T. Ryman, Sumit Rawal, Honghui Zhou, Margaret M. S. Thomson, Christine Li, Chetan Rathi, Dora B. Madhura, Ashit Trivedi, Wararat Limothai, Simone Kasek, Jocelyn H. Leu
Publikováno v:
Pharmaceutical Sciences Encyclopedia
This article presents a compilation of drug-drug interaction monographs involving therapeutic biologics. These include important “theoretical” drug-drug interactions along with well-established plausible mechanisms. These monographs are intended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac78bdb28035cb0b22c2aa179f86f213
https://doi.org/10.1002/9780470571224.pse487
https://doi.org/10.1002/9780470571224.pse487
Autor:
Roger A. Coulombe, Sumit Rawal
Publikováno v:
Toxicology and applied pharmacology. 254(3)
The extreme sensitivity of turkeys to aflatoxin B(1) (AFB(1)) is associated with efficient epoxidation by hepatic cytochromes P450 (P450) 1A5 and 3A37 to exo-aflatoxin B(1)-8,9-epoxide (exo-AFBO). The combined presence of 1A5 and 3A37, which obey dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0154b438bcd9f2913a0f5607693d760e
https://pubmed.ncbi.nlm.nih.gov/21616088
https://pubmed.ncbi.nlm.nih.gov/21616088