Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sumit Rathore"'
Autor:
Leena Sapra, Asha Bhardwaj, Zaffar Azam, Deekhsha Madhry, Bhupendra Verma, Sumit Rathore, Rupesh K. Srivastava
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 5, Pp 51-75 (2021)
In 2020, a novel strain of coronavirus (COVID-19) has led to a significant morbidity and mortality worldwide. As of the date of this writing, a total of 116 M cases has been diagnosed worldwide leading to 2.5 M deaths. The number of mortalities is di
Externí odkaz:
https://doaj.org/article/ebefc824e4d74d02b8583937e476dfa0
Autor:
Sheetal Kaul, Vivek Nair, Shweta Birla, Shikha Dhawan, Sumit Rathore, Vishal Khanna, Sheelu Lohiya, Shakir Ali, Shamim Mannan, Kirankumar Rade, Pawan Malhotra, Dinesh Gupta, Ashwani Khanna, Asif Mohmmed
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Diagnosis of latent tuberculosis infection (LTBI) using biomarkers in order to identify the risk of progressing to active TB and therefore predicting a preventive therapy has been the main bottleneck in eradication of tuberculosis. We compar
Externí odkaz:
https://doaj.org/article/24347c9fbf44466a9324f2f2058d49e0
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Lytic polysaccharide monooxygenases (LPMOs) mediate oxidative degradation of plant polysaccharides. The genes encoding LPMOs are most commonly arranged with one catalytic domain, while a few are found tethered to additional noncatalytic unit
Externí odkaz:
https://doaj.org/article/8781b26e349441a88d6387391882aec0
Autor:
Anil K Singh, Sumit Rathore, Yan Tang, Nathan E Goldfarb, Ben M Dunn, Vinoth Rajendran, Prahlad C Ghosh, Neelu Singh, N Latha, Brajendra K Singh, Manmeet Rawat, Brijesh Rathi
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139347 (2015)
A novel class of phthalimides functionalized with privileged scaffolds was designed, synthesized and evaluated as potential inhibitors of plasmepsin 2 (Ki: 0.99 ± 0.1 μM for 6u) and plasmepsin 4 (Ki: 3.3 ± 0.3 μM for 6t), enzymes found in the dig
Externí odkaz:
https://doaj.org/article/856273f96d4044048e6535b640b3820b
Molecular mechanisms of red cell invasion by the Plasmodium vivax parasite remain obscure since information on receptor-ligand interaction is scarce. Our lab had identified Basigin as receptor molecule for one of the important members of Pvfam “a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf33b9857c8ee189fc00ec8c6d2d572a
https://doi.org/10.21203/rs.3.rs-2319454/v1
https://doi.org/10.21203/rs.3.rs-2319454/v1
Autor:
Shaifali Jain, Mohd Asad, Reto Caldelari, Gaurav Datta, Shweta Singh, Sumit Rathore, Rebecca R. Stanway, Volker T. Heussler, Asif Mohmmed
The ATP-dependent ClpQY system is a prokaryotic proteasome-like machinery in the mitochondrion of malaria parasite, Plasmodium. This protease system is identified as a validated target for malaria intervention. Here we have identified drug-like small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ce636788b121d842a6bb2fdc86e94d
https://doi.org/10.1101/2022.05.12.491652
https://doi.org/10.1101/2022.05.12.491652
Publikováno v:
Integrated Omics Approaches to Infectious Diseases ISBN: 9789811606908
Malaria, a deadly disease caused by pathogen Plasmodium, is a global problem. After discovery of Plasmodium as a causative agent of malaria, the understanding of the malaria biology using conventional techniques was at slower pace as compared to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77d8015d2f26109227fa4c9e8a60e91
https://doi.org/10.1007/978-981-16-0691-5_26
https://doi.org/10.1007/978-981-16-0691-5_26
Autor:
Sumit Rathore, Zaffar Azam, Leena Sapra, Bhupendra Verma, Rupesh K. Srivastava, Asha Bhardwaj, Deekhsha Madhry
Publikováno v:
Frontiers in bioscience (Landmark edition). 26(5)
In 2020, a novel strain of coronavirus (COVID-19) has led to a significant morbidity and mortality worldwide. As of the date of this writing, a total of 116 M cases has been diagnosed worldwide leading to 2.5 M deaths. The number of mortalities is di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd6d368df02cfca3dc828795355fa5a
https://pubmed.ncbi.nlm.nih.gov/34027650
https://pubmed.ncbi.nlm.nih.gov/34027650
In late 2019, SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection started in Hubei province of China and now it has spread like a wildfire in almost all parts of the world except some. WHO named the disease caused by SARS-CoV-2 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d643b08490e07bed745fa765b828d3e
https://doi.org/10.1101/2020.05.11.20097923
https://doi.org/10.1101/2020.05.11.20097923
Autor:
Michael Theisen, Pawan Malhotra, Arunaditya Deshmukh, Susheel K. Singh, Ashutosh Panda, Sumit Rathore, Inderjeet Kaur, Asif Mohmmed, Gourab Paul, Bishwanath Kumar Chourasia
Publikováno v:
Infect Immun
Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ae8122270240c32a76997827b9a431
https://doi.org/10.1128/iai.00504-19
https://doi.org/10.1128/iai.00504-19