An emerging zoonotic disease to be concerned about - a review of the nipah virus

Autor: Sumit Paliwal, Suneet Shinu, Rubina Saha

Publikováno v: Journal of Health, Population and Nutrition, Vol 43, Iss 1, Pp 1-11 (2024)

Abstract The Nipah Virus (NiV) was discovered in 1999 in the Sungai Nipah region of Malaysia. It is one of many emerging bat-borne zoonotic viruses that threaten global health security. The Pteropus fruit bats are identified as the natural reservoirs

Externí odkaz: https://doaj.org/article/60246bedc1984114927f868448bfbe76

The PRSS3P2 and TRY7 deletion copy number variant modifies risk for chronic pancreatitis

Autor: Emmanuelle Masson, Maren Ewers, Sumit Paliwal, Kiyoshi Kume, Virginie Scotet, David N. Cooper, Vinciane Rebours, Louis Buscail, Karen Rouault, Amandine Abrantes, Lina Aguilera Munoz, Jérémie Albouys, Laurent Alric, Xavier Amiot, Isabelle Archambeaud, Solène Audiau, Laetitia Bastide, Julien Baudon, Guy Bellaiche, Serge Bellon, Valérie Bertrand, Karine Bideau, Kareen Billiemaz, Claire Billioud, Sabine Bonnefoy, Corinne Borderon, Barbara Bournet, Estelle Breton, Mathias Brugel, Guillaume Cadiot, Marine Camus, Marine Carpentier-Pourquier, Patrick Chamouard, Ulriikka Chaput, Jian-Min Chen, Franck Cholet, Dragos Marius Ciocan, Christine Clavel, Benoit Coffin, Laura Coimet-Berger, Simona Cosconea, Isabelle Creveaux, Adrian Culetto, Oussama Daboussi, Louis De Mestier, Thibault Degand, Christelle D'engremont, Bernard Denis, Solène Dermine, null Desgrippes, Augustin Drouet D'Aubigny, Raphaël Enaud, Alexandre Fabre, Claude Férec, Dany Gargot, Eve Gelsi, Elena Gentilcore, Rodica Gincul, Emmanuelle Ginglinger-Favre, Marc Giovannini, Cécile Gomercic, Hannah Gondran, Thomas Grainville, Philippe Grandval, Denis Grasset, Stéphane Grimaldi, Sylvie Grimbert, Hervé Hagege, Sophie Heissat, Olivia Hentic, Anne Herber-Mayne, Marc Hervouet, Solene Hoibian, Jérémie Jacques, Bénédicte Jais, Mehdi Kaassis, Stéphane Koch, Elodie Lacaze, Joël Lacroute, Thierry Lamireau, Lucie Laurent, Xavier Le Guillou, Marc Le Rhun, Sarah Leblanc, Philippe Levy, Astrid Lievre, Diane Lorenzo, Frédérique Maire, Kévin Marcel, Jacques Mauillon, Stéphanie Morgant, Driffa Moussata, Nelly Muller, Sophie Nambot, Bertrand Napoleon, Anne Olivier, Maël Pagenault, Anne-laure Pelletier, Olivier Pennec, Fabien Pinard, Mathieu Pioche, Bénédicte Prost, Lucille Queneherve, Noemi Reboux, Samia Rekik, Ghassan Riachi, Barbara Rohmer, Bertrand Roquelaure, Isabelle Rosa Hezode, Florian Rostain, Jean-Christophe Saurin, Laure Servais, Roxana Stan-Iuga, Clément Subtil, Jérémy Tanneche, Charles Texier, Lucie Thomassin, David Tougeron, Lucine Vuitton, Timothée Wallenhorst, Marc Wangerme, Hélène Zanaldi, Frank Zerbib, Seema Bhaskar, Kazuhiro Kikuta, G Venkat Rao, Shin Hamada, D Nageshwar Reddy, Atsushi Masamune, Giriraj Ratan Chandak, Heiko Witt

Publikováno v: Pancreatology. 23:48-56

PRSS1 and PRSS2 constitute the only functional copies of a tandemly-arranged five-trypsinogen-gene cluster (i.e., PRSS1, PRSS3P1, PRSS3P2, TRY7 and PRSS2) on chromosome 7q35. Variants in PRSS1 and PRSS2, including missense and copy number variants (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448aebd86496497b807c2bb323215d76
https://doi.org/10.1016/j.pan.2022.11.013

Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis

Autor: András Szabó, Prachand Issarapu, Emmanuelle Masson, Peter Bugert, Denise Lasher, Sumit Paliwal, Claudia Ruffert, Shin Hamada, K. Radha Mani, Helmut Laumen, Jian-Min Chen, Atsushi Masamune, David A. Groneberg, Katharina Seltsam, Kiyoshi Kume, Xunjun Xiao, Maren Ewers, Eriko Nakano, M. Michael Barmada, Tooru Shimosegawa, Jonas Rosendahl, Giriraj R. Chandak, Thomas Müller, Mark E. Lowe, Miklós Sahin-Tóth, Heiko Witt, Seema Bhaskar, David C. Whitcomb, Claude Férec

Publikováno v: American Journal of Gastroenterology. 114:974-983

OBJECTIVES. Premature activation of the digestive protease trypsin within the pancreatic parenchyma is a critical factor in the pathogenesis of pancreatitis. Alterations in genes that affect intra-pancreatic trypsin activity are associated with chron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f489f34cd4a57579c412918eeeab3
https://doi.org/10.14309/ajg.0000000000000051

Identification of a functional enhancer variant within the chronic pancreatitis‐associated SPINK1 c.101A>G (p.Asn34Ser)‐containing haplotype

Autor: Giriraj R. Chandak, David Neil Cooper, Emmanuelle Masson, Sumit Paliwal, Emmanuelle Génin, Hao Wu, Claude Férec, Prachand Issarapu, Wen-Bin Zou, Seema Bhaskar, Zhao-Shen Li, Arnaud Boulling, Jian-Min Chen, Zhuan Liao

Publikováno v: Human Mutation
Human Mutation, Wiley, 2017, 38 (8), pp.1014-1024. ⟨10.1002/humu.23269⟩

The haplotype harboring the SPINK1 c.101A>G (p.Asn34Ser) variant (also known as rs17107315:T>C) represents the most important heritable risk factor for idiopathic chronic pancreatitis identified to date. The causal variant contained within this risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceccb0ecd8c34e3d6f16d64d48586f2b
https://hal.inrae.fr/hal-02946985

Variants in CPA1 are strongly associated with early onset chronic pancreatitis

Autor: Sandra Steigenberger, Helmut Friess, Johanna Tebbing, Markus Braun, G Venkat Rao, Hartmut Schmidt, Matthias Löhr, David A. Groneberg, Seema Bhaskar, Melinda Bence, Niels Teich, Sumit Paliwal, Maren Ludwig, Sebastian Beer, Péter Hegyi, Jonas Rosendahl, Olfert Landt, Alexander Schneider, Gourdas Choudhuri, Eriko Nakano, Peter Kovacs, Andrea Schnúr, Robert Grützmann, Ivan Balascak, Markus Schuelke, Yoichi Kakuta, Volker Keim, Hana Algül, Eesh Bhatia, Richárd Szmola, Karolin Saum, Catherine Delaporte, Matthias Blüher, Frank Schmidt, Jian-Min Chen, Giriraj R. Chandak, Bertram Wiedenmann, Michael Stumvoll, Emmanuelle Masson, Andreas R. Janecke, András Szabó, Milan Macek, Denise Lasher, Peter Bugert, Claudia Pilsak, Renate Krüger, Ulrike Witt, Joachim Mössner, Hans Ulrich Schulz, Agnieszka Sobczynska-Tomaszewska, Kiyoshi Kume, Varghese Thomas, Klaus Peter Zimmer, Atsushi Masamune, Lukasz Durko, Miklós Sahin-Tóth, D. Nageshwar Reddy, Zoltán Rakonczay, Claude Férec, Heiko Witt, Tooru Shimosegawa, Florence Bühler, Thomas Müller, Daniel Bak, Grzegorz Oracz, Roland H. Pfützer

Publikováno v: Nature Genetics. 45:1216-1220

Chronic pancreatitis is an inflammatory disorder of the pancreas. We analyzed CPA1, encoding carboxypeptidase A1, in subjects with nonalcoholic chronic pancreatitis (cases) and controls in a German discovery set and three replication sets. Functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0943341dd278a2711a1150e25d047a45
https://doi.org/10.1038/ng.2730