Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sumit Kumar Chaturvedi"'
Autor:
Akhilendra Pratap Bharati, Mohd Kashif, Sumit Kumar Chaturvedi, Rizwan Hasan Khan, Abrar Ahmad
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229216 (2020)
RNA biogenesis and mRNA transport are an intricate process for every eukaryotic cell. SAGA, a transcriptional coactivator and TREX-2 are the two major complexes participate in this process. Sus1 is a transcription export factor and part of both the S
Externí odkaz:
https://doaj.org/article/da2fdac398974b13aeaa64902bc02774
Autor:
Sumit Kumar Chaturvedi, Nida Zaidi, Parvez Alam, Javed Masood Khan, Atiyatul Qadeer, Ibrar Ahmad Siddique, Shamoon Asmat, Yusra Zaidi, Rizwan Hasan Khan
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136528 (2015)
Amyloid fibril formation by proteins leads to variety of degenerative disorders called amyloidosis. While these disorders are topic of extensive research, effective treatments are still unavailable. Thus in present study, two anti-tuberculosis drugs,
Externí odkaz:
https://doaj.org/article/7b07138d675542089936e8179f4d279f
Autor:
Javed Masood Khan, Atiyatul Qadeer, Sumit Kumar Chaturvedi, Ejaz Ahmad, Syed Arif Abdul Rehman, Samudrala Gourinath, Rizwan Hasan Khan
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29694 (2012)
Sodium dodecyl sulphate (SDS), an anionic surfactant that mimics some characteristics of biological membrane has also been found to induce aggregation in proteins. The present study was carried out on 25 diverse proteins using circular dichroism, flu
Externí odkaz:
https://doaj.org/article/d3be5b33ee1b4eeaabe84afa98d25c60
Autor:
Huaying Zhao, Lewis E. Kay, Robert W. Harkness, Reza Esfandiary, Sonia Dragulin-Otto, Regina C. Adão, Arun Parupudi, Sumit Kumar Chaturvedi, Peter Schuck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Weak macromolecular interactions assume a dominant role in the behavior of highly concentrated solutions, and are at the center of a variety of fields ranging from colloidal chemistry to cell biology, neurodegenerative diseases, and manufacturing of
Autor:
Huaying Zhao, Sung Kim, Samuel C. To, Sumit Kumar Chaturvedi, Peter Schuck, Alan Rein, Siddhartha A. K. Datta
Publikováno v:
Journal of Biological Chemistry. 294:16480-16493
HIV-1 Gag is a highly flexible multidomain protein that forms the protein lattice of the immature HIV-1 virion. In vitro, it reversibly dimerizes, but in the presence of nucleic acids (NAs), it spontaneously assembles into virus-like particles (VLPs)
Publikováno v:
J Biol Chem
Tubulin, the subunit of microtubules, is a noncovalent heterodimer composed of one α- and one β-tubulin monomer. Both tubulins are encoded by multiple genes or composed of different isotypes, which are differentially expressed in different tissues
Publikováno v:
Journal of the American Chemical Society
Ultra-weak self-association can govern the macroscopic solution behavior of concentrated macromolecular solutions ranging from food products to pharmaceutical formulations and the cytosol. For example, it can promote dynamic assembly of multi-protein
Autor:
Parvez Alam, Ali S. Abdelhameed, Saima Nusrat, Sumit Kumar Chaturvedi, Mohammad Rehan Ajmal, Mohammad Yamin Siddiqi, Sadia Malik, Rizwan Hasan Khan
Publikováno v:
International journal of biological macromolecules. 157
Autor:
Ai Nguyen, Sonia Dragulin-Otto, Huaying Zhao, Kristian Juul-Madsen, Arun Parupudi, Reza Esfandiary, Sumit Kumar Chaturvedi, Peter Schuck, Thomas Vorup-Jensen
Publikováno v:
Chaturvedi, S K, Parupudi, A, Juul-Madsen, K, Nguyen, A, Vorup-Jensen, T, Dragulin-Otto, S, Zhao, H, Esfandiary, R & Schuck, P 2020, ' Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions ', mAbs, vol. 12, no. 1, 1810488 . https://doi.org/10.1080/19420862.2020.1810488
mAbs
article-version (VoR) Version of Record
mAbs
article-version (VoR) Version of Record
Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases. Besides their antigen specificity, therapeutic use also mandates control of their s
Autor:
Varish Ahmad, Bhupendra Kumar, Sunita Kumari, Mazin A. Zamzami, Sumit Kumar Chaturvedi, Mohd. Kashif, Rizwan Hasan Khan, Abrar Ahmad, Akhilendra Pratap Bharati
Publikováno v:
International journal of biological macromolecules. 159
Ntf2 is a nuclear envelope protein, which play a pivotal role in nucleocytoplasmic transport and mediates the nuclear import of RanGDP. It interacts with various nucleoporins along with Ran-GDP and part of a multicomponent system that assembles at th