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Akademický článek

Antinociceptive effect of selective G protein-gated inwardly rectifying K+ channel agonist ML297 in the rat spinal cord.

Autor: Masami Kimura, Hiroaki Shiokawa, Yuji Karashima, Makoto Sumie, Sumio Hoka, Ken Yamaura

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0239094 (2020)

The G protein-gated inwardly rectifying K+ (GIRK) channels play important signaling roles in the central and peripheral nervous systems. However, the role of GIRK channel activation in pain signaling remains unknown mainly due to the lack of potent a

Externí odkaz: https://doaj.org/article/58d01da0db964a0187a2167cb151caae

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Akademický článek

Prediction of hemodynamic fluctuations after induction of general anesthesia using propofol in non-cardiac surgery: a retrospective cohort study

Autor: Sho Kawasaki, Chikako Kiyohara, Shoji Tokunaga, Sumio Hoka

Publikováno v: BMC Anesthesiology, Vol 18, Iss 1, Pp 1-10 (2018)

Abstract Background Although propofol is a common anesthetic agent for the induction of general anesthesia, hemodynamic fluctuations are occasionally prominent during induction/intubation. The aims of this study were to determine the influential fact

Externí odkaz: https://doaj.org/article/6062b183e326433cb068cafab624a3ec

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Akademický článek

Effects of preoperative plasma exchange therapy with albumin replacement fluid on blood coagulation in patients undergoing ABO-incompatible living-donor kidney transplantation using rotational thromboelastometry

Autor: Kazuhiro Shirozu, Naoyuki Fujimura, Yuji Karashima, Mizuko Ikeda, Hidehisa Kitada, Yasuhiro Okabe, Kei Kurihara, Tomoko Henzan, Sumio Hoka

Publikováno v: BMC Anesthesiology, Vol 18, Iss 1, Pp 1-7 (2018)

Abstract Background ABO-incompatible living-donor kidney transplantation (LDKT) requires immunotherapy and plasma exchange therapy (PEX). PEX with albumin replacement fluid reportedly decreases fibrinogen levels. However, no reports have described th

Externí odkaz: https://doaj.org/article/3966d4f90d0a499591878e459829b377

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Akademický článek

Effectiveness of arginine vasopressin for the management of refractory hemorrhagic shock in a patient with autonomic dysreflexia caused by spinal cord injury

Autor: Tsukasa Shimauchi, Jun Maki, Jun Yoshino, Naoyuki Fujimura, Sumio Hoka

Publikováno v: JA Clinical Reports, Vol 4, Iss 1, Pp 1-3 (2018)

Abstract Background Arginine vasopressin has been used for the management of refractory vasodilatory shock. However, it is still unclear whether arginine vasopressin is useful for hypotension in patients with spinal cord injury. Case description A 78

Externí odkaz: https://doaj.org/article/cf5e06a5d04e43b49c6ff5695f46d101

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Akademický článek

Visceral fat, but not subcutaneous fat, is associated with lower core temperature during laparoscopic surgery.

Autor: Ryohei Miyazaki, Sumio Hoka, Ken Yamaura

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218281 (2019)

BackgroundPrevious studies suggest that lower BMI is a risk factor for intraoperative core hypothermia. Adipose tissue has a high insulation effect and is one of the major explanatory factors of core hypothermia. Accordingly, determining the respecti

Externí odkaz: https://doaj.org/article/da108fff67964a2bbc1287ad78f860a4

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Akademický článek

Thiamylal sodium increased inflammation and the proliferation of vascular smooth muscle cells

Autor: Ryohei Miyazaki, Sumio Hoka

Publikováno v: Korean Journal of Anesthesiology, Vol 69, Iss 3, Pp 262-269 (2016)

BackgroundThiamylal sodium is a common anesthetic barbiturate prepared in alkaline solution for clinical use. There is no previously reported study on the effects of barbiturates on the inflammation and proliferation of vascular smooth muscle cells (

Externí odkaz: https://doaj.org/article/4bb900c83e264a1685be1a69ace7c68a

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Akademický článek

Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension

Autor: Mariko Tanaka, Kohtaro Abe, Masahiko Oka, Keita Saku, Keimei Yoshida, Tomohito Ishikawa, Ivan F. McMurtry, Kenji Sunagawa, Sumio Hoka, Hiroyuki Tsutsui

Publikováno v: Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)

Abstract It is widely accepted that impaired bioavailability of endothelial nitric oxide (NO) plays a critical role in the pathophysiology of pulmonary arterial hypertension (PAH). However, there are published data that show that relatively many PAH

Externí odkaz: https://doaj.org/article/15295726e7944fc8b1476b953ec38a01

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Akademický článek

Direct Effect of Remifentanil and Glycine Contained in Ultiva® on Nociceptive Transmission in the Spinal Cord: In Vivo and Slice Patch Clamp Analyses.

Autor: Makoto Sumie, Hiroaki Shiokawa, Ken Yamaura, Yuji Karashima, Sumio Hoka, Megumu Yoshimura

Publikováno v: PLoS ONE, Vol 11, Iss 1, p e0147339 (2016)

BACKGROUND:Ultiva® is commonly administered intravenously for analgesia during general anaesthesia and its main constituent remifentanil is an ultra-short-acting μ-opioid receptor agonist. Ultiva® is not approved for epidural or intrathecal use in

Externí odkaz: https://doaj.org/article/d033addfdc81487ab508b5d42c2d994a

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