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pro vyhledávání: '"Sumin M. Zhao"'
Autor:
Marie A. Iannone, Lisa M. Leesnitzer, Andrew N. Billin, Timothy M. Willson, Kenneth H. Pearce, Robert T. Nolte, William J. Hoekstra, Sumin M. Zhao, Richard G. Buckholz, Millard H. Lambert, Barry G. Shearer, Cobb Jeffrey Edmond, Ryan P. Trump
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3916-3920
PPARgamma-activating thiazolidinediones and carboxylic acids such as farglitazar exert their anti-diabetic effects in part in PPARgamma rich adipose. Both pro- and anti-adipogenic PPARgamma ligands promote glucose and lipid lowering in animal models