Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sumiko Gamo"'
Autor:
Sumiko Gamo
Publikováno v:
International Congress Series. 1283:102-107
Drosophila mutants with altered sensitivity to diethyl ether have been used to elucidate the action mechanisms of volatile anesthetics. One of them, ethas311, was a mutation in calreticulin gene (crc) and showed resistance to isoflurane and hypersens
Publikováno v:
Journal of Bioscience and Bioengineering. 100:331-334
We showed that PC12 cells and 3T3 cells cultured in dishes were killed by illumination with visible white light from a halogen lamp at 7 x 10(4) lx for 5 min in the presence of either 10 microM hematoporphyrin or 2 microM methylene blue as a photosen
Autor:
Daisuke Yamamoto, Sumiko Gamo, Junya Tomida, Katsuyuki Dodo, Hitoshi Matakatsu, Yoshiharu Tanaka, Dai Keyakidani
Publikováno v:
Anesthesiology. 99:867-875
Background Various species, e.g., Caenorhabditis elegans, Drosophila melanogaster, and mice, have been used to explore the mechanisms of action of general anesthetics in vivo. The authors isolated a Drosophila mutant, ethas311, that was hypersensitiv
Autor:
Sumiko Gamo, Yoshiharu Tanaka
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 22:39-53
The para locus of Drosophila melanogaster encodes the alpha subunit of a voltage-sensitive sodium channel. Many of the mutants develop paralysis at the high temperature (37 degrees C) and are hypersensitive to diethylether anesthesia. We examined whe
Publikováno v:
Development. 126:5207-5216
The wing of Drosophila is separated into several sectors by the wing veins. Vein primordia are specified by the positional information provided by hedgehog and decapentaplegic in the wing imaginal disc and express the key regulatory gene rhomboid. On
Autor:
Miyuki Sakajo, Kumiko Ikeda, Eiji Nakashima-Tanaka, Yoshihiro H. Inoue, Sumiko Gamo, Yasuhiko Sakoyama
Publikováno v:
The Japanese Journal of Genetics. 65:277-285
Genetic and molecular investigations were carried out with 10 Japanese Drosophila melanogaster strains on P-M system of hybrid dysgenesis. The strains used here were collected in the years from 1952 to 1984 from various natural populations, and have
Publikováno v:
Current medicinal chemistry. 14(13)
On undergoing an operation under general anesthesia, we tend to lose consciousness, and on recovering from the anesthetic effect, we realize a memory loss during the operation, but do remember the happenings before the operation. It implies that the
Autor:
Sumiko Gamo
Publikováno v:
Current Drug Targets. 3
Generally speaking, we cannot fully understand the mechanisms of general anesthesia until the molecular mechanisms of consciousness are fully elucidated. Loss of consciousness induced by general anesthetics might involve sensation, motor activity, be
Publikováno v:
Toxicology letters.
1. For a genetical approach to the molecular mechanisms of general anesthesia, we isolated 14 Drosophila transposon tagging mutants which showed altered sensitivities to diethylether anesthesia. Two mutated genes were identified and analyzed for thei
Publikováno v:
International Congress Series. 1283:263-264
To identify the cause of resistance to diethylether anesthesia in Drosophila A-kinase anchor protein 200 (DAKAP200) mutant, Eth AR 206 , we tested genetic interaction with pka-RII EP2162 . The double mutant analysis suggested the existence of genetic