Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sumikazu Hamada"'
Autor:
Yuuki Nagao, Nobuyuki Hamanaka, Kanji Takahashi, Sumikazu Hamada, Kigen Kondo, Kazuhiko Torisu, Hitoshi Kato, Satoshi Shigeoka, Hidekado Tokumoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1087-1090
By incorporation of a pyridine moiety into compounds shown to be PGI 2 agonists, we have synthesized a series of compounds which also show potent thromboxane synthase inhibitory activity. Agents 9 and 14 with the 3-substituted pyridine moiety show a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc1cccc20a2e8c0cb40751e24554aeb
https://doi.org/10.1016/0960-894x(95)00171-o
https://doi.org/10.1016/0960-894x(95)00171-o
Publikováno v:
ChemInform. 23
2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which in turn react with acyl chlorides or chloroformates in the presence of cuprous iodide to afford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5f0e4edaf8061424248f427a27ac9b
https://doi.org/10.1002/chin.199233154
https://doi.org/10.1002/chin.199233154
Publikováno v:
Tetrahedron Letters. 33:337-340
2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which in turn react with acyl chlorides or chloroformates in the presence of cuprous iodide to afford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ab9a1dde2b3e49a4124d61a2a9739d
https://doi.org/10.1016/s0040-4039(00)74125-6
https://doi.org/10.1016/s0040-4039(00)74125-6