Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sumihiro Kunisue"'
Autor:
Masao Doi, Iori Murai, Sumihiro Kunisue, Genzui Setsu, Naohiro Uchio, Rina Tanaka, Sakurako Kobayashi, Hiroyuki Shimatani, Hida Hayashi, Hsu-Wen Chao, Yuuki Nakagawa, Yukari Takahashi, Yunhong Hotta, Jun-ichirou Yasunaga, Masao Matsuoka, Michael H. Hastings, Hiroshi Kiyonari, Hitoshi Okamura
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.
Externí odkaz:
https://doaj.org/article/c16b11b6441e475eb897bd5b32fd2eac
Publikováno v:
Endocrine Journal. 64:571-579
G-protein-coupled receptors (GPCRs) constitute an immensely important class of drug targets with diverse clinical applications. There are still more than 120 orphan GPCRs whose cognate ligands and physiological functions are not known. A set of circa
Autor:
Akira Hirasawa, Kaoru Goto, Yoshiaki Yamaguchi, Tianyu Wang, Genzui Setsu, Hitoshi Okamura, Masao Doi, Shumpei Nakagawa, Takahito Miyake, Sumihiro Kunisue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
G-protein-coupled receptors (GPCRs) are important drug targets with diverse therapeutic applications. However, there are still more than a hundred orphan GPCRs, whose protein functions and biochemical features remain unidentified. Gpr176 encodes a cl
Autor:
Takeshi Sano, Masao Doi, Akihiro Kanematsu, Sumihiro Kunisue, Jin Kono, Atsushi Sengiku, Nobuyuki Nishikawa, Hitoshi Okamura, Shigeki Shimba, Osamu Ogawa, Louis S. Liou, Masakatsu Ueda, Hiromitsu Negoro, Kojiro Tsujihana
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Day-night changes in the storage capacity of the urinary bladder are indispensable for sound sleep. Connexin 43 (Cx43), a major gap junction protein, forms hemichannels as a pathway of ATP in other cell types, and the urinary bladder utilizes ATP as
Autor:
Fumiyoshi Yamazaki, Takumi Ota, Hitoshi Okamura, Masao Doi, Yuuki Nakagawa, Hida Hayashi, Kazuki Okada, Daisuke Yarimizu, Iori Murai, Sumihiro Kunisue
Publikováno v:
Molecular and Cellular Biology. 34:3880-3894
The 3β-hydroxysteroid dehydrogenase (3β-HSD) is an enzyme crucial for steroid synthesis. Two different 3β-HSD isoforms exist in humans. Classically, HSD3B2 was considered the principal isoform present in the adrenal. However, we recently showed th
Autor:
Hiroshi Kiyonari, Hsu Wen Chao, Hitoshi Okamura, Yuuki Nakagawa, Naohiro Uchio, Yukari Takahashi, Yunhong Hotta, Masao Matsuoka, Sakurako Kobayashi, Rina Tanaka, Michael H. Hastings, Iori Murai, Hida Hayashi, Sumihiro Kunisue, Jun-ichirou Yasunaga, Masao Doi, Genzui Setsu, Hiroyuki Shimatani
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
G-protein-coupled receptors (GPCRs) participate in a broad range of physiological functions. A priority for fundamental and clinical research, therefore, is to decipher the function of over 140 remaining orphan GPCRs. The suprachiasmatic nucleus (SCN
Publikováno v:
Endocrine Journal; 2017, Vol. 64 Issue 6, p571-579, 9p
Autor:
Takumi Ota, Masao Doi, Fumiyoshi Yamazaki, Daisuke Yarimizu, Kazuki Okada, Iori Murai, Hida Hayashi, Sumihiro Kunisue, Yuuki Nakagawa, Hitoshi Okamura
Publikováno v:
Molecular & Cellular Biology; 10/15/2014, Vol. 34 Issue 20, p3880-3894, 15p