Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Sumihiro, Hase"'
Publikováno v:
FEBS Journal. 278:452-460
To investigate the relationship between phylogeny and glycan structures, we analyzed the structure of planarian N-glycans. The planarian Dugesia japonica, a member of the flatworm family, is a lower metazoan. N-glycans were prepared from whole worms
Autor:
Sumihiro Hase
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Herein, I describe pyridylamination for versatile analysis of sugar chains. The reducing ends of the sugar chains are tagged with 2-aminopyridine and the resultant chemically stable fluorescent derivatives are used for structural/functional analysis.
Autor:
Y. Mori, T. Nakashima, Shunji Natsuka, T. Hamuro, Sadaaki Iwanaga, Sumihiro Hase, T. Hamamoto
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:111-120
Summary. Background: Tissue factor pathway inhibitor (TFPI) is a physiological protease inhibitor that inhibits the initial reactions of the extrinsic blood coagulation pathway. Most TFPI in human plasma is associated with lipoproteins; however, the
A Novel 1,2-L-Fucosidase Acting on Xyloglucan Oligosaccharides is Associated with Endo- -Mannosidase
Publikováno v:
Journal of Biochemistry. 142:721-729
Endo-beta-mannosidase, which hydrolyses the Manbeta1-4GlcNAc linkage of N-glycans in an endo-manner, was discovered in plants. During the course of the purification of the enzyme from lily flowers, we found a higher molecular mass form of the enzyme
Autor:
Takafumi Aoki, Shin-ichi Nakakita, Sumihiro Hase, Kazunobu Moriguchi, Tatsuya Takemoto, Shunji Natsuka
Publikováno v:
Journal of Biochemistry. 142:213-227
We previously reported that zebrafishalpha1-3fucosyltrasferase 1 (zFT1) was expressed in embryos at the segmentation period, and was capable of synthesizing the Lewis x epitope [Gal beta1-4(Fuc alpha1-3)GlcNAc] [Kageyama et.al, J. Biochem., 125, 838-
Autor:
Hiroshi Teshima, Takeshi Ishimizu, Kyoko Sano, Sumihiro Hase, Kaoru Omichi, Takashi Uchida, Hironobu Hojo, Yoshiaki Nakahara
Publikováno v:
Journal of Biochemistry. 141:593-600
A unique O-glycan structure, Xylalpha1-3Xylalpha1-3Glcbeta1-O-Ser is found on the consensus sequence C-X-S-X-P-C (X denotes any amino acid) in epidermal growth factor (EGF)-like domains of plasma proteins such as clotting factor VII and IX. One of th
Publikováno v:
Analytical Biochemistry. 352:182-187
UDP-galacturonic acid, the activated form of galacturonic acid (GalUA), is synthesized both de novo and by salvage pathways. The UDP-GalUA pyrophosphorylase gene involved in the salvage pathway has not been identified. Here we show that UDP-sugar pyr
Autor:
Sumihiro Hase, Takeshi Ishimizu
Publikováno v:
Trends in Glycoscience and Glycotechnology. 18:39-47
N-配糖体のコア構造中のManβ1-4GlcNAc結合を加水分解するエンド-β-マンノシダーゼ(EC3.1.2.152) が高等植物より見いだされた。我々は、最近、エンド-β-マンノシダーゼの精製、遺伝子クロー
Publikováno v:
The Journal of Biochemistry. 138:209-213
Some mutants of Caenorhabditis elegans show altered patterns of ectopic binding with wheat germ agglutinin (WGA). Some of these mutants also have defects of morphogenesis and movement during development. To clarify the structures of WGA-ligands in C.
Publikováno v:
FEBS Journal. 272:1660-1668
Endo-beta-mannosidase is an endoglycosidase that hydrolyzes only the Man beta 1-4GlcNAc linkage of the core region of N-linked sugar chains. Recently, endo-beta-mannosidase was purified to homogeneity from Lilium longiflorum (Lily) flowers, its corre