Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sumi Shanmugam"'
Autor:
Ivanka Toudjarska, Jürgen Soutschek, Vandana Sood, Kevin McClintock, Akin Akinc, Birgit Bramlage, Matthew N. Fedoruk, Timothy Racie, Adam Judge, Ian MacLachlan, Hans-Peter Vornlocher, Lorne R. Palmer, Lloyd Jeffs, Kieu Lam, Sumi Shanmugam, William Zedalis, Tracy Zimmermann, Ingo Röhl, Matthias John, Ed Yaworski, Jens Harborth, Amy C.H. Lee, Muthiah Manoharan, Stephan Seiffert, James Heyes, David Bumcrot, Amanda J. Wheat, Victor Koteliansky, Lubomir Nechev
Publikováno v:
Nature. 441:111-114
The opportunity to harness the RNA interference (RNAi) pathway to silence disease-causing genes holds great promise for the development of therapeutics directed against targets that are otherwise not addressable with current medicines. Although there
Autor:
Kevin Fitzgerald, Maria Frank-Kamenetsky, Tracy S Zimmermann, Jay Horton, Akin Akinc, Birgit Bramlage, David Bumcrot, Jens Harborth, Matthias John, Victor Kotelianski, Muthiah Manoharan, Martin Maier, Lubomir Nechev, Timothy Racie, Ingo Roehl, Stephan Seiffert, Sumi Shanmugam, Jurgen Soutschek, Ivanka Toudjarska, Hans-Peter Vornlocher, William Zedalis
Publikováno v:
Circulation. 116
Delivery of small interfering RNAs (siRNAs) in vivo , using clinically relevant modes of administration, is critical for the advancement of RNA interference (RNAi) therapeutics. In this work, we demonstrate systemic delivery of siRNAs and potent in v