Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sumi Chonan"'
Autor:
Masato Takahashi, Koji Yamamoto, Eiji Munetomo, Akira Hiratate, Ayako Mikami, Hidetaka Saito, Yuji Takaoka, Akio Suzuki, Kiyokazu Kitano, Sumi Chonan, Masako Saito-Hori, Hiroshi Fukushima
Publikováno v:
Bioorganicmedicinal chemistry. 16(7)
Dipeptidyl peptidase IV (DPP-IV) inhibitors are promising antidiabetic drugs, and several drugs are in the developmental stage. We previously reported that the introduction of fluorine to the 4-position of 2-cyanopyrrolidine enhanced the DPP-IV inhib
Autor:
Hiromitsu Yoshimura, Sumi Chonan, Koji Yamamoto, Nannan Gao, Xinggao Zhang, Koko Sugawara, Masako Saitoh, Shigeru Murakami, Hajime Takashima, Shiuji Saito, Mariko Sato-Watanabe, J S Yang
Publikováno v:
FEBS Letters. (1-3):55-59
Transforming growth factor-beta (TGF-beta), a multifunctional cytokine which is involved in extracellular matrix modulation, has a major role in the pathogenesis and progression of fibrotic diseases. We now report the effects of ursolic acid on TGF-b