Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sumera Perveen"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The 5′-mRNA-cap formation is a conserved process in protection of mRNA in eukaryotic cells, resulting in mRNA stability and efficient translation. In humans, two methyltransferases, RNA cap guanine-N7 methyltransferase (hRNMT) and cap-spec
Externí odkaz:
https://doaj.org/article/f2a59a48a16a44dd9a3e57e9add01eed
Autor:
Serah W. Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl H. Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Cbl-b is a RING-type E3 ubiquitin ligase that is expressed in several immune cell lineages, where it negatively regulates the activity of immune cells. Cbl-b has specifically been identified as an attractive target for cancer immunotherapy d
Externí odkaz:
https://doaj.org/article/cb03406153a543aca75baa69d0a3b0e3
Autor:
Yu Zong, Nicole Weiss, Ke Wang, Alexandra E. Pagano, Søren Heissel, Sumera Perveen, Jian Huang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Arginine and lysine, frequently appearing as a pair on histones, have been proven to carry diverse modifications and execute various epigenetic regulatory functions. However, the most context‐specific and transient effectors of these marks
Externí odkaz:
https://doaj.org/article/47298e61d3d842fd905d0b4d5040fd49
Autor:
Serah Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
Cbl-b is a RING-type E3 ubiquitin ligase that is expressed in several immune cell lineages, where it negatively regulates the activity of immune cells. Cbl-b has specifically been identified as an attractive target for cancer immunotherapy due to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db4dbbe02fc24621e78187a7f8d2166
https://doi.org/10.1101/2023.05.05.539612
https://doi.org/10.1101/2023.05.05.539612
Autor:
Peter Loppnau, Minkui Luo, Pegah Ghiabi, Albina Bolotokova, Irene Chau, Fengling Li, Jing Liu, Matthieu Schapira, Karla J. F. Satchell, Sumera Perveen, Ke Wang, Aliakbar Khalili Yazdi, Paul V. Fish, Jian Jin, Peter Brown, Deyao Li, Masoud Vedadi, David Smil, Kanchan Devkota, Taraneh Hajian
Publikováno v:
Slas Discovery
bioRxiv
bioRxiv
The COVID-19 pandemic has clearly brought the healthcare systems world-wide to a breaking point along with devastating socioeconomic consequences. The SARS-CoV-2 virus which causes the disease uses RNA capping to evade the human immune system. Non-st
Autor:
Aliakbar Khalili Yazdi, Paknoosh Pakarian, Sumera Perveen, Taraneh Hajian, Vijayaratnam Santhakumar, Albina Bolotokova, Fengling Li, Masoud Vedadi
Publikováno v:
ACS infectious diseases. 8(8)
SARS-CoV-2 non-structural protein 13 (nsp13) is a highly conserved helicase and RNA 5'-triphosphatase. It uses the energy derived from the hydrolysis of nucleoside triphosphates for directional movement along the nucleic acids and promotes the unwind
Autor:
Masoud Vedadi, Pegah Ghiabi, Sumera Perveen, Kanchan Devkota, Fengling Li, Aliakbar Khalili Yazdi, Albina Bolotokova, Taraneh Hajian
Publikováno v:
Slas Discovery
Frequent outbreaks of novel coronaviruses (CoVs), highlighted by the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, necessitate the development of therapeutics that could be easily and effectively administered worldwid
Autor:
S. M. Saqlan Naqvi, Tehmina Ahsan Khan, Bushra Ijaz, Rabia Naz, Muhammad Zeeshan Hyder, Sumera Perveen, Tayyaba Yasmin, Humaira Shaheen
Publikováno v:
In Vitro Cellular & Developmental Biology - Plant. 57:907-922
The OsRGLP1 gene was overexpressed under the control of CaMV 35S promoter in tomato (Solanum lycopersicum L.) plants using Agrobacterium-mediated transformation. The transgene expression was validated using RT-qPCR (real-time quantitative polymerase
Autor:
Fengling Li, Pegah Ghiabi, Taraneh Hajian, Martin Klima, Alice Shi Ming Li, Aliakbar Khalili Yazdi, Irene Chau, Peter Loppnau, Maria Kutera, Almagul Seitova, Albina Bolotokova, Ashley Hutchinson, Sumera Perveen, Evzen Boura, Masoud Vedadi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1867:130319
Autor:
Sumera Perveen, Carlos A. Zepeda-Velázquez, David McLeod, Richard Marcellus, Mohammed Mohammed, Megha Abbey, Deeba Ensan, Dimitrios Panagopoulos, Viacheslav Trush, Elisa Gibson, Aiping Dong, Levon Halabelian, Gennady Poda, Julie Owen, Ahmed Aman, Taira Kiyota, Ahmed Mamai, Cheryl H. Arrowsmith, Peter J. Brown, Matthieu Schapira, Rima Al-awar, Masoud Vedadi
RBBP4 is a nuclear WD40 motif-containing protein widely implicated in various cancers and a putative drug target. It interacts with multiple proteins within diverse complexes such as nucleosome remodeling and deacetylase (NuRD) complex and polycomb r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cf4448a4ef25f58c7154a98ab95c5c
https://doi.org/10.1101/2022.01.05.475077
https://doi.org/10.1101/2022.01.05.475077