Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sumei Xu"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionNonalcoholic or metabolism-associated fatty liver disease (NAFLD or MAFLD) and colorectal polyps are chronic conditions strongly linked to lifestyle factors. However, the precise causal link between NAFLD or MAFLD and the development of c
Externí odkaz:
https://doaj.org/article/4f166c4d55694b889201f0d58a36a40c
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveThe objective of this investigation was to elucidate the key active compounds and molecular mechanisms underlying the therapeutic potential of airpotato yam rhizome (AYR) in colorectal cancer (CRC) treatment.MethodsBy utilizing network pharm
Externí odkaz:
https://doaj.org/article/5825d3ca82e241368fe387b143f82e7e
Autor:
Daizhuang Peng, Sumei Xu, Ting Zou, Yahui Wang, Wenjuan Ouyang, Yalan Zhang, Chengmei Dong, Dai Li, Jie Guo, Qiuying Shen, Xiaolei Hu, Wenzhi Zhou, Xiaomin Li, Qun Qin
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background AD16 is a Class 1.1 new drug candidate for Alzheimer’s disease (AD), which has demonstrated potential benefits in AD by reducing neuroinflammation in preclinical studies. Herein, the pharmacokinetics (PK), safety, and tolerabili
Externí odkaz:
https://doaj.org/article/358e8135b8854330bee03778f3c368aa
Publikováno v:
Molecules, Vol 28, Iss 19, p 6995 (2023)
In previous studies, we reported compound 1 (5-chloro-N-(4-oxo-2,2-dipropyl-3,4-dihydro-2H-benzo[e][1,3]oxazin-6-yl)-1H-indole-2-carboxamide) as a novel PYGB inhibitor, and found that it had better anti-ischemic brain injury activity. In this study,
Externí odkaz:
https://doaj.org/article/11d696feebbb42548638a6871ab53d6d
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundThe prevalence of NAFLD is increasing annually. The early diagnosis and control are crucial for the disease. Currently, metabolic indicators are always used clinically as an auxiliary diagnosis of NAFLD. However, the prevalence of NAFLD is
Externí odkaz:
https://doaj.org/article/576e88da8dc8463cb4b008f7cbeda91a
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Colon cancer is a worldwide leading cause of cancer-related mortality, and the prognosis of colon cancer is still needed to be improved. This study aimed to construct a prognostic model for predicting the prognosis of colon cancer
Externí odkaz:
https://doaj.org/article/f14522f4e31b46d7a23fddfd63225758
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Shenqi pill (SQP), a famous traditional Chinese medicine (TCM) herbal formula derived from Jinguiyaolue (Synopsis of Prescriptions of the Golden Chamber), has long been used to treat kidney yang deficiency syndrome. According to the TCM treatment pri
Externí odkaz:
https://doaj.org/article/2faa4a751254425482709e5b584d5070
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundIn China, the prevalence and mortality of colorectal cancer (CRC) have always been high, and more than 95% of CRC cases have evolved from colorectal polyps (CPs), especially adenoma. Early detection and treatment of CPs through colonoscopy
Externí odkaz:
https://doaj.org/article/f7ff6bc967d4463981ee0046f8f4b8e3
Autor:
Beihui He, Jianping Jiang, Zheng Shi, Liyan Wu, Junbin Yan, Zheng Chen, Minmin Luo, Dawei Cui, Sumei Xu, Maoxiang Yan, Shuo Zhang, Zhiyun Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss , Pp 111183- (2021)
Background: Our previous studies found that Pure total flavnoids from citrus (PTFC) can effectively improve non-alcoholic steatohepatitis (NASH) in mice. Here, we discuss on the mechanism of PTFC in treating NASH with focus on the regulation of the g
Externí odkaz:
https://doaj.org/article/b95ae8df7c634e07800d262598be6822
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Objective: The impact of non-steroidal anti-inflammatory drugs (NSAIDs) to damage the small intestine has been well known. Mica, one kind of natural clay, has been widely marketed in China for the treatment of gastric diseases. However, the role and
Externí odkaz:
https://doaj.org/article/511ac4b08c16413cb98eb60836cea18c