Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sumeet Deshmukh"'
Autor:
Charlotte E. Moss, Simon A. Johnston, Joshua V. Kimble, Martha Clements, Veryan Codd, Stephen Hamby, Alison H. Goodall, Sumeet Deshmukh, Ian Sudbery, Daniel Coca, Heather L. Wilson, Endre Kiss-Toth
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114073- (2024)
Summary: Macrophages are central innate immune cells whose function declines with age. The molecular mechanisms underlying age-related changes remain poorly understood, particularly in human macrophages. We report a substantial reduction in phagocyto
Externí odkaz:
https://doaj.org/article/4b1acb9fd5b841acafd7c00ff65e1ec6
Autor:
Tristan Grogan, T. Bao, David Elashoff, I. Silacheva, Galyna Bondar, Mario C. Deng, Neha S. Kulkarni, Taisuke Nakade, Sumeet Deshmukh
Publikováno v:
Expert Review of Precision Medicine and Drug Development. 6:139-145
Biological determinants of survival in advanced heart failure (AdHF) are linked to systems biological properties of disease severity including age, comorbidities, and frailty. We hypothesize that a...
Autor:
Swapna Satam, Sumeet Deshmukh, Ian Sudbery, Oscar Villacanas, Endre Kiss-Toth, Chiara Niespolo, Ziyanda Shologu, Jessica Johnston, Heather L. Wilson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Front. Immunol. 11:574046 (2020)
Frontiers in Immunology
Front. Immunol. 11:574046 (2020)
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase. TRIB1 regulates polarization of macrophages and dysregulated Trib1 expression i
Autor:
Ian Sudbery, Sumeet Deshmukh, Chiara Niespolo, Juan Salamanca Viloria, Oscar Villacanas Perez, Endre Kiss-Toth, Heather L. Wilson
Publikováno v:
Basic Science.
Introduction MiR-101-3p has been implicated in the regulation of macrophage cholesterol efflux and pro-inflammatory genes by directly targeting ABCA1 and MKP-1, which are both downregulated in atherosclerosis. By using bioinformatic analysis we ident
Autor:
Mario C. Deng, Tristan Grogan, Sumeet Deshmukh, David Elashoff, T. Bao, T. Nakade, I. Silacheva, N.S. Kulkarni, Galyna Bondar
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S230
Purpose We previously reported that preoperative differentially expressed genes can predict short-term recovery and long-term survival in patients after mechanical circulatory support (MCS)-surgery. Here, we aimed to train and independently validate