Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sumbal Arooj"'
Autor:
Guixiang Liao, Yuxiang Fu, Sumbal Arooj, Muhammad Khan, Xianming Li, Maosheng Yan, Zihuang Li, Hongli Yang, Tao Zheng, Ruilian Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMelanoma brain metastases (BMs) are associated with poor prognosis and are the main cause of mortality in melanoma patients. BRAF inhibitors have shown intracranial activity in both treatment-naïve and previously treated BM patients. We ai
Externí odkaz:
https://doaj.org/article/1d74e898f39e4c3888daa65879308efc
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Radiotherapy is the mainstay of brain metastasis (BM) management. Radiation necrosis (RN) is a serious complication of radiotherapy. Bevacizumab (BV), an anti-vascular endothelial growth factor monoclonal antibody, has been increa
Externí odkaz:
https://doaj.org/article/fdc886d7d9014e7e9cc9a0922e66a861
Autor:
Guixiang Liao, Yuting Qian, Sumbal Arooj, Zhihong Zhao, Maosheng Yan, Zihuang Li, Hongli Yang, Tao Zheng, Gang Li, Xianming Li, Muhammad Khan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundRadiation therapy (RT) is the mainstay of brain metastases (BMs), and anti-PD-1 blockade has led to intracranial responses in non-small cell lung carcinoma (NSCLC) patients with BMs.ObjectiveThis study aimed to evaluate the efficacy and saf
Externí odkaz:
https://doaj.org/article/064f3e3d29cb4a59bbe1a542000f090d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Co-inhibitory B7-CD28 family member proteins negatively regulate T cell responses and are extensively involved in tumor immune evasion. Blockade of classical CTLA-4 (cytotoxic T lymphocyte-associated antigen-4) and PD-1 (programmed cell death protein
Externí odkaz:
https://doaj.org/article/d2cb90a757d54a45a5450b841ec42b03
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundRadiation brain necrosis (RBN) is a serious complication in patients receiving radiotherapy for intracranial disease. Many studies have investigated the efficacy and safety of bevacizumab in patients with RBN. In the present study, we syste
Externí odkaz:
https://doaj.org/article/45cc669c995f4e97b95d3991cf1ae018
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundBRAF inhibitors have improved the outcome for patients with BRAF mutant metastatic melanoma and have shown intracranial responses in melanoma brain metastases. Stereotactic radiosurgery (SRS) is being used as a local treatment for melanoma
Externí odkaz:
https://doaj.org/article/cc98d1cf92b0495c8cd8d15193385119
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Programmed death protein 1 (PD-1) interaction with PD-L1 deliver immunosuppressive environment for tumor growth, and its blockade with directed monoclonal antibodies (anti-PD-1/anti-PD-L1) has shown remarkable clinical outcome. Lately, their soluble
Externí odkaz:
https://doaj.org/article/be00a28edbaa4d76a8e86bcd83df1d95
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundIntracranial activity of lapatinib has been demonstrated in several studies in patients with human epidermal growth factor receptor-2 positive breast cancers (HER-2+ BC). Stereotactic radiosurgery (SRS) has been increasingly used as the loc
Externí odkaz:
https://doaj.org/article/1e3264597ed44bfca37cff3f980ba123
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Targeted therapy has transformed the outcome for patients with metastatic renal cell carcinoma. Their efficacy and safety have also been demonstrated in brain metastatic RCC. Preclinical evidence suggests synergism of radiation and tyrosi
Externí odkaz:
https://doaj.org/article/6f9318f3d2bc48549d03c9ad0ca13206
Autor:
Muhammad Khan, Sumbal Arooj, Rong Li, Yunhong Tian, Jian Zhang, Jie Lin, Yingying Liang, Anan Xu, Ronghui Zheng, Mengzhong Liu, Yawei Yuan
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Randomized controlled trials have failed to report any survival advantage for WBRT combined with SRS in the management of brain metastases, despite the enhanced local and distant control in comparison to each treatment alone. Literature review have r
Externí odkaz:
https://doaj.org/article/4a635392013849ff8ebd787ecddaa9a5