The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

Autor: Steven F. Abcouwer, Bruna Miglioranza Scavuzzi, Phillip E. Kish, Dejuan Kong, Sumathi Shanmugam, Xuan An Le, Jingyu Yao, Heather Hager, David N Zacks

Publikováno v: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)

Abstract The retinal pigment epithelium (RPE) maintains photoreceptor viability and function, completes the visual cycle, and forms the outer blood-retinal barrier (oBRB). Loss of RPE function gives rise to several monogenic retinal dystrophies and c

Externí odkaz: https://doaj.org/article/487206ebf56c47e6aeee4f489f4822ae

Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion

Autor: Jérémie Canonica, Richard Foxton, Marina Garcia Garrido, Cheng-Mao Lin, Sabine Uhles, Sumathi Shanmugam, David A. Antonetti, Steven F. Abcouwer, Peter D. Westenskow

Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)

IntroductionClinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and maintains vision improvements, with strong durability, through 2 years in

Externí odkaz: https://doaj.org/article/eb987d4d51b2489f96e27b6a29635f5b

Morphological variations of the cystic duct and its clinical significance: A cadaveric study

Autor: Sumathi Shanmugam, Kalaiyarasi Subbiah, Sivakami Thiagarajan

Publikováno v: National Journal of Clinical Anatomy, Vol 10, Iss 3, Pp 155-159 (2021)

Background: Anatomical variations of the cystic duct (CD) are common with an incidence of 18%–23% and are commonly encountered during cholecystectomy. The prevalence of such variations in our region is recorded so as to create awareness to avoid si

Externí odkaz: https://doaj.org/article/4979cf137be1490c979dbf62e95a4efa

The determinants of donor safety and product quality in optimization of apheresis granulocyte harvest: An experience from a tertiary care oncology centre in India.

Autor: Ojha S; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: sojha@actrec.gov.in., Poojary M; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: mpoojary@actrec.gov.in., Mokalikar U; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: mokalikarumakant1234@gmail.com., Sumathi SH; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: sumathish@actrec.gov.in., Kumar A; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: arun.actrec@yahoo.co.in., Gupta AM; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: dr.abhaymgupta@gmail.com., Saha S; Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India. Electronic address: ssaha@actrec.gov.in.

Publikováno v: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2022 Oct; Vol. 61 (5), pp. 103445. Date of Electronic Publication: 2022 Apr 07.