Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sumathi Chittamuru"'
Autor:
Laxman Desai, Timothy Murphy, Sumathi Chittamuru, Roseanne Wexler, Andrew A. Taylor, Sara Anne Little
Publikováno v:
Clinical Cancer Research. 27:P39-P39
The ability to control the proliferation and cell death by inhibiting specific target kinase offers the opportunity to apply targeted therapies in the treatment of cancer. It has been found that (S)-valine-thiazole-derived compounds such as NEOS-223
Publikováno v:
Journal of Clinical Oncology. 36:e14509-e14509
e14509Background: Cyclin dependent kinases (CDK) play a vital role in cell cycling and proliferation. Altered expression of these kinases in malignant cells results in deregulation of cell cycle ac...
Autor:
Aravamudan S. Gopalan, Gloria Martinez, Hollie K. Jacobs, Sumathi Chittamuru, Timothy N. Lambert
Publikováno v:
Tetrahedron Letters. 48:567-571
The reactions of the electrophilic iminium ester mesylate salt 1 with alcohols, phenols and thiols has been investigated. In the presence of base, thiols, phenols and thiophenol react with 1 to give the corresponding ether linked HOPO derivatives in
Publikováno v:
Tetrahedron Letters. 43:7379-7383
The preparation of the new electrophilic iminium ester mesylate salt 5 and its reaction with primary and secondary amines have been investigated. Aniline, t-butylamine, and secondary amines react with 5 via ring opening to give the corresponding HOPO
Autor:
Alvin L. Crumbliss, Hollie K. Jacobs, Sumathi Chittamuru, Suraj Dhungana, Aravamudan S. Gopalan, James M. Harrington
Publikováno v:
Inorganic chemistry. 49(18)
The synthesis of a novel class of exocyclic bis- and tris-3,2-hydroxypyridinone (HOPO) chelators built on N(2) and N(3) aza-macrocyclic scaffolds and the thermodynamic solution characterization of their complexes with Fe(III) are described. The chela
Publikováno v:
ChemInform. 33
The preparation of the new electrophilic iminium ester mesylate salt 5 and its reaction with primary and secondary amines have been investigated. Aniline, t-butylamine, and secondary amines react with 5 via ring opening to give the corresponding HOPO