Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Sumantra, Chattarji"'
Autor:
Laura Simões de Oliveira, Heather E. O’Leary, Sarfaraz Nawaz, Rita Loureiro, Elizabeth C. Davenport, Paul Baxter, Susana R. Louros, Owen Dando, Emma Perkins, Julien Peltier, Matthias Trost, Emily K. Osterweil, Giles E. Hardingham, Michael A. Cousin, Sumantra Chattarji, Sam A. Booker, Tim A. Benke, David J. A Wyllie, Peter C. Kind
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) cause a severe neurological disorder characterised by early-onset epileptic seizures, autism and intellectual disability (ID). Impaired hippocampal function has
Externí odkaz:
https://doaj.org/article/ae255dae432e41748c4459655b5be30f
Autor:
Nuria Garcia, Rufus Mitchell-Heggs, Kapil Saxena, Sumantra Chattarji, Peter Kind, Simon Schultz, Richard Morris
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S92- (2023)
Externí odkaz:
https://doaj.org/article/29e14cfded004d538d26f664b51d02c4
Autor:
Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji, Emma R. Wood, Oliver Hardt, Peter C. Kind
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however
Externí odkaz:
https://doaj.org/article/3d9e90cbc8e047a6a47ce223c07a8fd8
Autor:
Shreya Das Sharma, Bharath Kumar Reddy, Rakhi Pal, Tuula E. Ritakari, James D. Cooper, Bhuvaneish T. Selvaraj, Peter C. Kind, Siddharthan Chandran, David J.A. Wyllie, Sumantra Chattarji
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112344- (2023)
Summary: Pre-clinical studies of fragile X syndrome (FXS) have focused on neurons, with the role of glia remaining largely underexplored. We examined the astrocytic regulation of aberrant firing of FXS neurons derived from human pluripotent stem cell
Externí odkaz:
https://doaj.org/article/07393c8817104f9e9f38c64e50f84baa
Autor:
Pravesh Parekh, Gaurav Vivek Bhalerao, John P. John, G. Venkatasubramanian, Biju Viswanath, Naren P. Rao, Janardhanan C. Narayanaswamy, Palanimuthu T. Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Odity Mukherjee, Meera Purushottam, Bhupesh Mehta, Thennarasu Kandavel, B. Binukumar, Jitender Saini, Deepak Jayarajan, A. Shyamsundar, Sydney Moirangthem, K.G. Vijay Kumar, Jayant Mahadevan, Bharath Holla, Jagadisha Thirthalli, Bangalore N. Gangadhar, Pratima Murthy, Mitradas M. Panicker, Upinder S. Bhalla, Sumantra Chattarji, Vivek Benegal, Mathew Varghese, Janardhan Y.C. Reddy, Padinjat Raghu, Mahendra Rao, Sanjeev Jain
Publikováno v:
NeuroImage, Vol 264, Iss , Pp 119768- (2022)
When data is pooled across multiple sites, the extracted features are confounded by site effects. Harmonization methods attempt to correct these site effects while preserving the biological variability within the features. However, little is known ab
Externí odkaz:
https://doaj.org/article/32466111ceb44dd6beef30879cb2b3f2
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
There is accumulating evidence for contrasting patterns of stress-induced morphological and physiological plasticity in glutamatergic synapses of the hippocampus and amygdala. The same chronic stress that leads to the formation of dendritic spines in
Externí odkaz:
https://doaj.org/article/f8aa35c2073441d5aed2d918eb671824
Publikováno v:
Neurobiology of Stress, Vol 18, Iss , Pp 100442- (2022)
Stress elicits divergent patterns of structural plasticity in the amygdala and hippocampus. Despite these contrasting effects, at least one of the immediate consequences of stress – elevated levels of extracellular glutamate – is similar in both
Externí odkaz:
https://doaj.org/article/6f3ead66c3c946afb7e8e7a7761e8404
Autor:
Shreya Das Sharma, Rakhi Pal, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga, Durga J. Srinivasan, Loren Ornelas, Dhruv Sareen, Matthew R. Livesey, Gary J. Bassell, Clive N. Svendsen, Peter C. Kind, Siddharthan Chandran, Sumantra Chattarji, David J. A. Wyllie
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder. Notwithstanding the extensive studies using rodent and other pre-clinical models of F
Externí odkaz:
https://doaj.org/article/be1ddd0d597d4f079af05cef176f7f96
Autor:
Preeti Madhav Kute, Sarayu Ramakrishna, Nagammal Neelagandan, Sumantra Chattarji, Ravi. S. Muddashetty
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and Moloney Leukemia Virus 10 (MOV10
Externí odkaz:
https://doaj.org/article/12820b830204453a909e6bbf585c35a6
Autor:
Kanika Gupta, Sumantra Chattarji
Publikováno v:
Neurobiology of Stress, Vol 14, Iss , Pp 100292- (2021)
There is accumulating evidence that stress triggers specific temporal patterns of morphological plasticity in the amygdala, a brain area that plays a pivotal role in the debilitating emotional symptoms of stress-related psychiatric disorders. Acute i
Externí odkaz:
https://doaj.org/article/1f2a83267d8d4f9fb83c3e2e59e27915