Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Sumanirole"'
Autor:
René A. J. Crans, Elise Wouters, Marta Valle-León, Jaume Taura, Caio M. Massari, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/137c8a0904b543838a2edd3f05da1ad5
Autor:
René A. J. Crans, Elise Wouters, Marta Valle-León, Jaume Taura, Caio M. Massari, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor control deficits, which is associated with the loss of striatal dopaminergic neurons from the substantia nigra. In parallel to dopaminergic denervation, there is an inc
Externí odkaz:
https://doaj.org/article/d78fedc97b28444c849c62f284c7c02b
Akademický článek
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Akademický článek
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Autor:
Xinglin Ruan, Fabin Lin, Dihang Wu, Lina Chen, Huidan Weng, Jiao Yu, Yingqing Wang, Ying Chen, Xiaochun Chen, Qinyong Ye, Fangang Meng, Guoen Cai
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
Background: Movement fluctuations are the main complication of Parkinson's disease (PD) patients receiving long-term levodopa (L-dopa) treatment. We compared and ranked the efficacy and safety of dopamine agonists (DAs) with regard to motor fluctuati
Autor:
Jeffrey D. Neighbors, Michelle V. Green, Jillian S. Weissenrieder, Jessie L. Reed, Emily J. Koubek, Raymond J. Hohl, George Lucian Moldovan
Publikováno v:
Pharmacology. 105:19-27
Background: Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult to treat because most anticancer therapeutics do not readily penetrate into the brain due to the tight control at the cere
Autor:
Fernando J. Sialana, Ana Paunkov, Harald Höger, Daniel Daba Feyissa, Predrag Kalaba, Gert Lubec, Ephrem Engidawork, Volker Korz, Erik Keimpema
Publikováno v:
Behavioural Brain Research. 362:173-180
Spatial reference memory is known to be modulated by the dopaminergic system involving different brain regions. Here, we sought to identify the contribution of D1 (D1R) and D2 (D2R)-like dopamine receptor signaling on learning and memory in a food re
Autor:
Adrian M. Guerrero, Amy Hauck Newman, Hideaki Yano, Lei Shi, Vivek Kumar, Alexander F. Hoffman, Alessandro Bonifazi, Carl R. Lupica
Publikováno v:
ACS Pharmacology & Translational Science
The discovery of functionally biased and physiologically beneficial ligands directed toward G-protein coupled receptors (GPCRs) has provided the impetus to design dopamine D2 receptor (D2R) targeted molecules that may be therapeutically advantageous
Autor:
René A. J. Crans, Elise Wouters, Marta Valle-León, Jaume Taura, Caio M. Massari, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
FRONTIERS IN PHARMACOLOGY
Universidad de Barcelona
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
FRONTIERS IN PHARMACOLOGY
A corrigendum was published at https://doi.org/10.3389/fphar.2022.1075433
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor control deficits, which is associated with the loss of striatal dopaminergic neurons from t
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor control deficits, which is associated with the loss of striatal dopaminergic neurons from t
Publikováno v:
Life sciences. 261
Aims Cerebral ischemic stroke leads to mitochondrial alterations which are key factors for initiation of various cascades resulting in neuronal damage. Dopamine D2 receptor (D2R) agonist, Sumanirole (SUM) has been reported to possess anti-inflammator