Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sumana, Choudhury"'
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103141- (2023)
DNMT1 overexpression is reported in disorders like schizophrenia, bipolar, epilepsy and multiple cancer types. Here, we used non-homologous recombination to generate R1Dnmt1WT-1, a mouse embryonic stem cell (ESC) line carrying a Dnmt1 cDNA transgene
Externí odkaz:
https://doaj.org/article/f493620c83d447b4999baf2e91c097d4
Autor:
Sumana Choudhury, K. Naga Mohan
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102561- (2021)
DNMT1 Y495C is the most common mutation associated with hereditary sensory and autonomic neuropathy type 1E, and dementia. Here we employed non-homologous recombination and generated a mouse embryonic stem cell line carrying a transgene expressing DN
Externí odkaz:
https://doaj.org/article/205a3af9726848a68fbb5c2b69de0fec
Autor:
Sonal Saxena, Pranay Amruth Maroju, Sumana Choudhury, Vidhya Chitta Voina, Poonam Naik, Kavitha Gowdhaman, Poornima Kkani, Kiranmai Chennoju, S. Ganesh Kumar, C. Ramasubramanian, G. Prasad Rao, Trinath Jamma, Kumar Pranav Narayan, K. Naga Mohan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://doaj.org/article/28798b94df534441895eee949185e1f1
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106242- (2020)
Defects in epigenetic mechanisms are well-recognized in multiple neurodevelopmental disorders including Schizophrenia (SZ). In addition to aberrant epigenetic marks, dysregulated epigenetic machinery was also identified among the contributory factors
Externí odkaz:
https://doaj.org/article/7603f1be052846f4a78e6060cc55c5f7
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101073- (2020)
Investigation on the effects of disease-associated mutations on neurodevelopment is an essential approach to understand the molecular basis of neurological disorders and can be achieved by generating suitable animal models. However, some of the mutat
Externí odkaz:
https://doaj.org/article/ef6b32d957d34b529b9f7f653a674d10
Autor:
Shuvra Das, Mohammed Maruf Ul Quader, Pranab Kumar Chowdhury, Salina Haque, Mitra Datta, Tanjina Hoq, Sumana Choudhury
Publikováno v:
Chattagram Maa-O-Shishu Hospital Medical College Journal. 19:28-32
Background: Mild or subclinical hypothyroidism may coexist with NephroticSyndrome (NS). But persistence of this hypothyroidism is related with remission ofproteinuria. Objectives of the study is to compare thyroid function status (FT4 andTSH) in the
Autor:
Sumana Choudhury, Kommu Naga Mohan, Sonal Saxena, Pranay Amruth Maroju, Anuhya Anne, Lov Kumar
Publikováno v:
Epigenomics. 13(19)
Aim: To study the effects of DNMT1 overexpression on transcript levels of genes dysregulated in schizophrenia and on genome-wide methylation patterns. Materials & methods: Transcriptome and DNA methylome comparisons were made between R1 (wild-type) a
Publikováno v:
2021 IEEE 4th International Conference on Computing, Power and Communication Technologies (GUCON).
Switched Reluctance motor (SRM) are accepting critical consideration from industries, due to its straight forward structure; low-cost manufactur ability and dependability make it better than other electric machines. For adjustable speed tasks, the dr
Autor:
Poornima Kkani, G Prasad Rao, Vidhya Chitta Voina, C Ramasubramanian, Kavitha Gowdhaman, Sonal Saxena, K. Naga Mohan, Pranay Amruth Maroju, S. Ganesh Kumar, Trinath Jamma, Kiranmai Chennoju, Sumana Choudhury, Poonam Naik, Kumar Pranav Narayan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Autor:
Rusty Kelley Ph.D., Andrew Bruce, Tom Spencer, Eric Werdin, Roger Ilagan, Sumana Choudhury, Elias Rivera, Shay Wallace, Kelly Guthrie, Manuel Jayo, Fengfeng Xu, Anjali N. Rao, Benjamin D. Humphreys, Sharon Presnell, Tim Bertram
Publikováno v:
Cell Transplantation, Vol 22 (2013)
New treatment paradigms that slow or reverse progression of chronic kidney disease (CKD) are needed to relieve significant patient and healthcare burdens. We have shown that a population of selected renal cells (SRCs) stabilized disease progression i
Externí odkaz:
https://doaj.org/article/7ca09f8c5c4946ad93f5e619fe9d10b5